MAPK ligand 1
MAPK ligand 1 is an apoptosis inducer and Bcl-xL/MAPK ligand that can be used to synthesize the Bcl-xL-targeted PROTAC degrader (HY-176740). MAPK ligand 1 triggers apoptosis through the mitochondrial pathway, MAPK pathway, reduction of mitochondrial membrane potential and elevation of reactive oxygen species levels. MAPK ligand 1 inhibits colony formation and migration of cancer cells, as well as angiogenesis of endothelial cells. MAPK ligand 1 can be used in the research of hepatocellular carcinoma.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 2566503-77-1
- 分子式: C20H13NO3
- 分子量:315.32
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
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Bcl-xL |
化学情報
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CAS 番号 2566503-77-1
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分子量 315.32
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分子式 C20H13NO3
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SMILES
OC(C1=CC2=C(NC(C3=CC=CC4=C3C=CC=C4)=CC2=O)C=C1)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)