TRPC3 agonist-1
TRPC3 agonist-1 (compound 4n) is a selective and competitive TRPC3 channel agonist. TRPC3 agonist-1 binds at L2 site of hTRPC3.
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- CAS 番号: 1589567-51-0
- 分子式: C22H23F3N4O3
- 分子量:448.44
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
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TRPC3 |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | EC50 |
0.019 μM
Compound: 4n
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Agonist activity at human TRPC3 expressed in HEK293 cells assessed as induction of membrane depolarization measured for 2.5 mins in presence of 0.5 mM Ca2+ by FLIPR membrane potential dye-based fluorescence assay
Agonist activity at human TRPC3 expressed in HEK293 cells assessed as induction of membrane depolarization measured for 2.5 mins in presence of 0.5 mM Ca2+ by FLIPR membrane potential dye-based fluorescence assay
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[PMID: 28395140] |
化学情報
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CAS 番号 1589567-51-0
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分子量 448.44
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分子式 C22H23F3N4O3
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SMILES
O=C(N1CCC(C2=NC3=C(C4=CC=C(C(F)(F)F)C=C4)C(C)=NN3C(O)=C2)CC1)OCC
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
TRPC3 agonist-1 関連分類
HY-179489 関連分類
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