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Cat. No.: HY-111467

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Mcl1-IN-4

Mcl1-IN-4 is an inhibitor of Mcl1 with an IC₅₀ of 0.2 μM.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 1580484-04-3
화학식: C₂₈H₂₆N₂O₅S
분자량:502.58

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

Mcl1-IN-4 Chemical Structure

CAS No.: 1580484-04-3

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재고

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

Mcl1-IN-4 is an inhibitor of Mcl1 with an IC₅₀ of 0.2 μM.

IC₅₀ & Target

IC50: 0.2 μM (Mcl1)^[1]

All Bcl-2 Family Isoforms :

In Vitro

Mcl1-IN-4 is compound 19^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 1580484-04-3
분자량 502.58
화학식 C₂₈H₂₆N₂O₅S
SMILES

CC1=C2C(C=CC=C2)=C(C3=CC(NS(C4=CC(N5CCOCC5)=CC=C4)(=O)=O)=C(C(O)=O)C=C3)C=C1
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Petros AM, et al. Fragment-based discovery of potent inhibitors of the anti-apoptotic MCL-1 protein. Bioorg Med Chem Lett. 2014 Mar 15;24(6):1484-8. [Content Brief]

[2]. Petros A, et al. Fragment-based Discovery of Potent Inhibitors of the Anti-Apoptotic MCL-1 Protein. Bioorg Med Chem Lett, 24 (6), 1484-1488.

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

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Amount: USD 0.00

Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
Chemical Information
순도&문서
References

상품명:
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Mcl1-IN-4

All Bcl-2 Family Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

Mcl1-IN-4 Related Classifications

HY-111467 Related Classifications