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Cat. No.: HY-161662

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ALK5-IN-80

ALK5-IN-80 (Compound 29b) is a selective ALK5 inhibitor with an IC₅₀ value of 3.7 nM. ALK5-IN-80 can be used for cancer research.

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CAS No.: 3039952-63-8
화학식: C₂₁H₁₈FN₇O₂S
분자량:451.48

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

ALK5-IN-80 Chemical Structure

CAS No.: 3039952-63-8

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

ALK5-IN-80 (Compound 29b) is a selective ALK5 inhibitor with an IC₅₀ value of 3.7 nM. ALK5-IN-80 can be used for cancer research^[1].

IC₅₀ & Target

IC50: 3.7 nM (ALK5), 73.7 nM (ALK1), 183 nM (ALK2), >10000 nM (ALK3), 3690 nM (ALK4), >10000 nM (ALK6), 6344 nM (ACTR2B)^[1]

All TGF-β Receptor Isoforms :

Chemical Information

CAS No. 3039952-63-8
분자량 451.48
화학식 C₂₁H₁₈FN₇O₂S
SMILES

O=C(N)C1=C(C2=CC(C(C)=O)=CN2)SC(N(C3CC3)C4=CN(N=C4)C5=C(F)C=NC=C5)=N1
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Arai M, et al. Design and synthesis of novel thiazole-derivatives as potent ALK5 inhibitors. Bioorg Med Chem Lett. 2024 May 16;108:129797. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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Amount: USD 0.00

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References

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ALK5-IN-80

All TGF-β Receptor Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

ALK5-IN-80 Related Classifications

HY-161662 Related Classifications