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Cat. No.: HY-N19754

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Cladospirone B

Cladospirone B is a secondary metabolite of the endophytic fungus Lasiodiplodia theobromae. Cladospirone B exhibits trypanocidal activity, with a MIC of 17.8 µM against Trypanosoma brucei. Cladospirone B can be used in the research of African human trypanosomiasis (sleeping sickness).

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CAS No.: 307503-97-5
화학식: C₂₀H₁₄O₆
분자량:350.32

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Cladospirone B Chemical Structure

CAS No.: 307503-97-5

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- Cellular Effect
- In Vitro
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Biological Activity

제품 설명

All Parasite Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
A2780	IC₅₀	10 μM Compound: 18	Cytotoxicity against human A2780 cells by MTT assay Cytotoxicity against human A2780 cells by MTT assay	[PMID: 25237727]

In Vitro

Cladospirone B shows no activity against bacteria and fungi^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 307503-97-5
분자량 350.32
화학식 C₂₀H₁₄O₆
SMILES

O[C@H]1C2(OC3=CC=CC4=C3C(O2)=CC=C4)C5=C(O)C=CC(O)=C5C(C1)=O
Structure Classification
- Others
Initial Source
- Microorganisms
Berkleasmium sp.
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Kamal N, et al. Metabolomics-Guided Isolation of Anti-trypanosomal Metabolites from the Endophytic Fungus Lasiodiplodia theobromae. Planta Med. 2017;83(6):565-573. [Content Brief]

Calculators

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Cladospirone B

All Parasite Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

Cladospirone B Related Classifications

HY-N19754 Related Classifications