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Cat. No.: HY-149307

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CYCA-117-70

CYCA-117-70 is a DCAF1 ligand (K_D: 70 μM). CYCA-117-70 is an ideal chemical handles for PROTACs recruiting DCAF1.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 1958262-04-8
화학식: C₁₉H₂₄FN₅O
분자량:357.43

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

CYCA-117-70 Chemical Structure

CAS No.: 1958262-04-8

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

제품 설명

CYCA-117-70 is a DCAF1 ligand (K_D: 70 μM). CYCA-117-70 is an ideal chemical handles for PROTACs recruiting DCAF1^[1].

All Ligands for E3 Ligase Isoforms :

Chemical Information

CAS No. 1958262-04-8
분자량 357.43
화학식 C₁₉H₂₄FN₅O
SMILES

FC1=CC(N(C2)CCCC2NC3=NC=NC(N4CCOCC4)=C3)=CC=C1
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Kimani SW, et al. Discovery of a Novel DCAF1 Ligand Using a Drug-Target Interaction Prediction Model: Generalizing Machine Learning to New Drug Targets. J Chem Inf Model. 2023 Jul 10;63(13):4070-4078. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

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Concentration _(start) Concentration _(start)

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Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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Biological Activity
- 제품 설명
Chemical Information
순도&문서
References

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CYCA-117-70

All Ligands for E3 Ligase Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

CYCA-117-70 Related Classifications

HY-149307 Related Classifications