NRX-103095
Based on 1 Customer Validation
NRX-103095 is an enhancer of the interaction between β-catenin, and its cognate E3 ligase, SCFβ-TrCP. NRX-103095 enhances the binding of pSer33/Ser37 β-catenin peptide for β-TrCP with an EC50 of 163 nM.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- Purity: 99.68%
- CAS No.: 2763260-38-2
- 화학식: C22H16Cl2F3N3O3S
- 분자량:530.35
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보관:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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용액&용해도
- 순도&문서
- References
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Help & FAQs
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Biological Activity
EC50: 163 nM (β-catenin:β-TrCP Interaction)[1]
Chemical Information
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CAS No. 2763260-38-2
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Appearance Solid
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분자량 530.35
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화학식 C22H16Cl2F3N3O3S
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Color Off-white to light yellow
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SMILES
O=C(C1=CC=CC(NC(C2=C(C=C(NC2=O)C(F)(F)F)SC3=C(C=CC=C3Cl)Cl)=O)=C1)N(C)C
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
용액&용해도
DMSO : 100 mg/mL (188.55 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (276 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.8855 mL | 9.4277 mL | 18.8555 mL | 47.1387 mL |
| 5 mM | 0.3771 mL | 1.8855 mL | 3.7711 mL | 9.4277 mL | |
| 10 mM | 0.1886 mL | 0.9428 mL | 1.8855 mL | 4.7139 mL | |
| 15 mM | 0.1257 mL | 0.6285 mL | 1.2570 mL | 3.1426 mL | |
| 20 mM | 0.0943 mL | 0.4714 mL | 0.9428 mL | 2.3569 mL | |
| 25 mM | 0.0754 mL | 0.3771 mL | 0.7542 mL | 1.8855 mL | |
| 30 mM | 0.0629 mL | 0.3143 mL | 0.6285 mL | 1.5713 mL | |
| 40 mM | 0.0471 mL | 0.2357 mL | 0.4714 mL | 1.1785 mL | |
| 50 mM | 0.0377 mL | 0.1886 mL | 0.3771 mL | 0.9428 mL | |
| 60 mM | 0.0314 mL | 0.1571 mL | 0.3143 mL | 0.7856 mL | |
| 80 mM | 0.0236 mL | 0.1178 mL | 0.2357 mL | 0.5892 mL | |
| 100 mM | 0.0189 mL | 0.0943 mL | 0.1886 mL | 0.4714 mL |
NRX-103095 Related Classifications
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