PAR 4 (1-6) (human)
PAR 4 (1-6) human, a hexapeptide, is a fragment of protease-activated receptor 4 (PAR4). PAR 4 (1-6) TFA acts as a PAR4-specific agonist.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- CAS No.: 225779-44-2
- 화학식: C28H41N7O9
- 분자량:619.67
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
PAR 4 (1-6) (GYPGQV) stimulats [3H]-thymidine incorporation in SMC. At 500 μM, the peptide increases DNA synthesis 2.5 fold above controls. A comparable mitogenic effect is obtained after stimulation of the SMC by 10 nM thrombin or 100 μM SFLLRN, respectively[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 225779-44-2
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분자량 619.67
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화학식 C28H41N7O9
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Synonyms
GYPGQV
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Sequence
Gly-Tyr-Pro-Gly-Gln-Val
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Sequence Shortening
GYPGQV
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
[1]. H Andersen, et al. Protease-activated receptor 1 is the primary mediator of thrombin-stimulated platelet procoagulant activity. Proc Natl Acad Sci U S A. 1999 Sep 28;96(20):11189-93. [Content Brief]
[2]. E Bretschneider, et al. Evidence for functionally active protease-activated receptor-4 (PAR-4) in human vascular smooth muscle cells. Br J Pharmacol. 2001 Apr;132(7):1441-6. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PAR 4 (1-6) (human) Related Classifications
HY-P1313 Related Classifications
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