PRMT5-MTA-IN-3
PRMT5-MTA-IN-3 (Compound P2A) is an orally active and selective protein arginine methyltransferase 5 (PRMT5) inhibitor. PRMT5-MTA-IN-3 inhibits cell proliferation in the MTAP-deficient colorectal cancer HCT - 116 cell line with an IC50 value of 5 nM. PRMT5-MTA-IN-3 is promising for research of cancers, especially for MTAP-deficient tumors, such as colorectal cancer, non-small cell lung cancer, pancreatic cancer.
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- CAS No.: 3028674-29-2
- 화학식: C19H17F3N6O3
- 분자량:434.37
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Histone Methyltransferase Isoforms
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Biological Activity
Chemical Information
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CAS No. 3028674-29-2
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분자량 434.37
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화학식 C19H17F3N6O3
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SMILES
CN1N=CC2=C1C(N)=NC=C2NC(C(N([C@@H]3COC4=CC(C(F)(F)F)=CC=C43)C)=O)=O
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)