Aminophylline (Standard)
Aminophylline (Standard) is the analytical standard of Aminophylline (HY-B0140). This product is intended for research and analytical applications. Aminophylline is a competitive phosphodiesterase 3/4 (PDE3/4) inhibitor. Aminophylline also acts as an adenosine receptor antagonist. Aminophylline elevates intracellular cAMP levels via competitive inhibition of PDE3 and PDE4, antagonizes adenosine A1 receptor (ADORA1), regulates intracellular calcium signaling and synaptic vesicle cycling, upregulates the PPAR signaling pathway, and downregulates glutamatergic synaptic pathways simultaneously. Aminophylline can be used in research related to major depressive disorder, epilepsy, and chronic obstructive pulmonary disease (COPD).
For research use only. We do not sell to patients.
- Purity: 98%
- CAS No.: 317-34-0
- Formula: C7H8N4O2·1/2C2H8N2
- Molecular Weight:210.22
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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Chemical Information
- Purity & Documentation
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Help & FAQs
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 317-34-0
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Molecular Weight 210.22
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Formula C7H8N4O2·1/2C2H8N2
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SMILES
O=C(N1C)N(C)C2=C(N=CN2)C1=O.NCCN.[1/2]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Samante FI, et al. Potential antidepressant properties of aminophylline in male mice exposed to chronic restraint stress. Pharmacological reports : PR. 2026 Jun;78(3):748-761. [Content Brief]
[2]. Czuczwar SJ, et al. Effect of aminophylline on the protective action of common antiepileptic drugs against electroconvulsions in mice. Epilepsia. 1986;27(3):204-8. [Content Brief]
[3]. Mengozzi G, et al. Comparative bioavailability of two sustained-release theophylline formulations in the dog. Pharmacological research. 1998 Dec;38(6):481-5. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Aminophylline (Standard) Related Classifications
HY-B0140R Related Classifications
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- Aminophylline (Standard)
- 317-34-0
- Reference Standards
- Phosphodiesterase (PDE)
- Adenosine Receptor
- PPAR
- calcium signaling
- serotonin transporter
- major depressive disorder
- synaptic vesicle cycle
- adenosine receptor
- PPAR signaling
- glutamatergic synapse
- beagle dogs
- phosphodiesterase 4
- phosphodiesterase 3
- Inhibitor
- inhibitor
- inhibit