IPM-N001
IPM-N001 is a carbonic anhydrase IX (CAIX) ligand with a Kd value of <0.0337 nM for hCAIX. When radio-conjugated with 68Ga, IPM-N001 serves as a CAIX-targeted radionuclide tracer. [68Ga]Ga-IPM-N001 exhibits excellent tumor uptake and significantly improves the tumor-to-background ratio in PET/CT imaging studies using OS-RC-2 tumor-bearing mice. IPM-N001 can be used for the research of clear cell renal cell carcinoma.
For research use only. We do not sell to patients.
- Formula: C99H140N24O31S3
- Molecular Weight:2258.51
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All Radionuclide-Drug Conjugates (RDCs) Isoforms
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Biological Activity
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hCA IX <0.0337 nM (Kd) |
IPM-N001 exhibits high binding affinity for purified hCAIX, with a Kd value of <0.0337 nM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 2258.51
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Formula C99H140N24O31S3
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SMILES
NC([C@@H](NC([C@H](CO)NC([C@H](CC1=CNC2=C1C=CC=C2)NC([C@H]([C@@H](C)O)CC([C@H](CC(C)C)NC([C@@H](NC([C@H](CC(O)=O)NC([C@@H]3N(C([C@H](CCC(O)=O)N4)=O)CCC3)=O)=O)CC5=CC=CC(NC(CCCS(N)(=O)=O)=O)=C5)=O)=O)=O)=O)=O)CSCC6=CC(CSC[C@H](NC([C@H](CCC(NCCCN7C=CN=C7[N+]([O-])=O)=O)NC(CN8CCN(C(CN9CCN(CC(O)=O)CCN(CC(O)=O)CCN(CC(O)=O)CC9)=O)CC8)=O)=O)C4=O)=CC=C6)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
IPM-N001 Related Classifications
HY-P11737 Related Classifications
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