Phospholipase D, Streptomyces chromofuscus
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Phospholipase D, Streptomyces chromofuscus (PLD) is an enzyme of the phospholipase superfamily, which widely exists in bacteria, yeast, plants, animals and viruses, and is often used in biochemical research. Phospholipase D can catalyze the hydrolysis of phosphodiester bonds in glycerophospholipids to produce phosphatidic acid and soluble choline. Phospholipase D is involved in a variety of disease-related processes, including diabetes, atherogenesis, obesity, tumorigenesis, immune response, and neuroendocrine function.
For research use only. We do not sell to patients.
- CAS No.: 9001-87-0
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Phospholipase Isoforms
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Biological Activity
Product Information
This product is an enzyme preparation refined from natural strains through deep liquid fermentation, and contains highly active phospholipase. It can specifically catalyze the hydrolysis of the phosphatidyl diester bond at the end of phosphatidylcholine to generate phosphatidic acid and choline.
Temperature range: effective temperature range 35°C-55°C, optimum temperature 40°C-50°C
pH range: effective pH range pH4.0-7.5, optimum pH 5.0-6.0
Instructions
Diluted with water.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
3.1.4.4
≥50000 U/mL
One unit is defined as the amount of enzyme that will release 1 μmol of choline from L-αphosphatidylcholine per hour at pH 8.0 and 37°C
Chemical Information
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CAS No. 9001-87-0
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Appearance Liquid
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Color Light yellow to yellow
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SMILES
[Phospholipase D, Streptomyces chromofuscus]
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Synonyms
PLD
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent & Solubility
H2O : ≥ 100 mg/mL
* "≥" means soluble, but saturation unknown.
Purity & Documentation
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Data Sheet (265 KB)
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SDS (419 KB)
- English - EN (419 KB)
- Français - FR (419 KB)
- Deutsch - DE (419 KB)
- Norwegian - NO (419 KB)
- Español - ES (419 KB)
- Swedish - SV (419 KB)
- Italian - IT (419 KB)
- Korean - KR (419 KB)
- Portuguese - PT (419 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)