Phospholipase D, cabbage
Phospholipase D, cabbage is a phospholipase D of the PLD superfamily found in cabbage, acting as a phosphodiesterase and signaling enzyme with activity toward phosphatidylcholine. Phospholipase D hydrolyzes phosphatidylcholine to phosphatidic acid and choline, and catalyzes transphosphatidylation reactions. Phospholipase D can be used for the research of myocardial disease, ischemic heart disease, congestive heart failure, diabetic cardiomyopathy, cardiac hypertrophy, vascular abnormalities, breast cancer, gastric cancer, renal cancer, colorectal cancer.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 9001-87-0
-
Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biologische Aktivität
-
Chemical Information
- Reinheit & Dokumentation
- Verweise
-
Help & FAQs
Alle Phospholipase Isoform-spezifische Produkte anzeigen
More
Biologische Aktivität
Cabbage phospholipase D exhibits substrate specificity, and it does not hydrolyze rac. 1,2-diacylglycerol-3-phosphocholine with a 2-alkyl substitution at the sn-2 position[1].
Phospholipase D, cabbage is soluble at pH 5.6.
Phospholipase D hydrolyzes choline phospholipids to quantify the incorporation of propargylcholine[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS. Nr. 9001-87-0
-
SMILES
[Phospholipase D, cabbage]
-
Versand
Room temperature in continental US; may vary elsewhere.
-
Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Shukla SD, Halenda SP. Phospholipase D in cell signalling and its relationship to phospholipase C. Life sciences. 1991;48(9):851-66. [Content Brief]
[2]. Selvy PE, et al. Phospholipase D: enzymology, functionality, and chemical modulation. Chem Rev. 2011 Oct 12;111(10):6064-119. [Content Brief]
[3]. Jao CY, Roth M, Welti R, et al.. Metabolic labeling and direct imaging of choline phospholipids in vivo. Proceedings of the National Academy of Sciences of the United States of America. 2009 Sep 08;106(36):15332-7. [Content Brief]
[4]. Tappia PS, et al. Oxidative stress and redox regulation of phospholipase D in myocardial disease. Free Radic Biol Med. 2006 Aug 1;41(3):349-61. [Content Brief]
[5]. Foster DA, Xu L. Phospholipase D in cell proliferation and cancer. Mol Cancer Res. 2003 Sep;1(11):789-800. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Phospholipase D, cabbage Related Classifications
HY-P2812B Related Classifications
Powered by Bioz