PPARδ agonist 13

PPARδ agonist 13 is a potent, selective and orally active PPARδ agonist with an EC50 values of 0.50 nM. PPARδ agonist 13 binds to the PPARδ ligand-binding pocket and upregulates PPARδ target gene expression. PPARδ agonist 13 inhibits renal fibroblast activation, restores fatty acid oxidation, and attenuates TGF-β1-induced renal fibroblast activation. PPARδ agonist 13 exhibits anti-renal fibrosis effects in a mouse model of unilateral ureteral obstruction. PPARδ agonist 13 can be used for the research of renal fibrosis.

For research use only. We do not sell to patients.

  • CAS No.: 3056618-93-7
  • Formula: C27H24F3N2NaO4
  • Molecular Weight:520.48
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

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100 mg

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