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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
14 Results for "
A22
" in MedChemExpress (MCE) Product Catalog:
Products (14)
14 Results for "A22" in MCE Product Catalog:
1
1 Cited Publications
Synonyms: 4-Chlorobenzyl carbamimidothioate hydrochloride
MP265 (4-Chlorobenzyl carbamimidothioate hydrochloride) is a structural analogue of A22 but is less toxic. MP265 is a MreB inhibitor .
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Cat. No.: HY-D1005A22
CAS No.: 9003-11-6
Synonyms: PEG-PPG-PEG, 14600 (Average)
Synonyms: A22 hydrochloride
MreB Perturbing Compound A22 hydrochloride (A22 hydrochloride) is a reversible MreB inhibitor and antimicrobial agent that exhibits bacteriostatic activity against Escherichia coli, with low activity against Gram-positive bacteria. MreB Perturbing Compound A22 hydrochloride rapidly and reversally delocalizes MreB from the helical/circular structures in cells, impairs MreB function, and reduces the binding of MreB to the chromosomal region proximal to the replication origin. MreB Perturbing Compound A22 hydrochloride alters the cell morphology of caulobacters to round/lemon-shaped, slows caulobacter growth, blocks their cell division, and induces the formation of spherical morphology, asymmetric division, and anucleate cells in Escherichia coli. MreB Perturbing Compound A22 hydrochloride is used for studies related to bacterial rod-shaped morphology determination, chromosome segregation, and cell division mechanisms .
Cat. No.: HY-130337
CAS No.: 91032-26-7
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Teicoplanin A2-2 is a glycopeptide antibiotic. Teicoplanin A2-2 exhibits antibacterial activity, particularly against coagulase-negative staphylococci (CNS). Teicoplanin A2-2 inhibits bacterial cell wall synthesis by competitively binding to the terminal D-Ala-D-Ala peptide bonds in the cell wall synthesis process, leading to bacterial death. Teicoplanin A2-2 can be used for research into bacterial resistance mechanisms and the development of new antibiotics .
Cat. No.: HY-118773R
CAS No.: 22816-60-0
Synonyms: A22 hydrochloride (Standard)
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MreB Perturbing Compound A22 hydrochloride (Standard) is the analytical standard for MreB Perturbing Compound A22 hydrochloride (HY-118773). This product is intended for research and analytical applications. MreB Perturbing Compound A22 hydrochloride (A22 hydrochloride) is a reversible MreB inhibitor and antimicrobial agent that exhibits bacteriostatic activity against Escherichia coli, with low activity against Gram-positive bacteria. MreB Perturbing Compound A22 hydrochloride rapidly and reversally delocalizes MreB from the helical/circular structures in cells, impairs MreB function, and reduces the binding of MreB to the chromosomal region proximal to the replication origin. MreB Perturbing Compound A22 hydrochloride alters the cell morphology of caulobacters to round/lemon-shaped, slows caulobacter growth, blocks their cell division, and induces the formation of spherical morphology, asymmetric division, and anucleate cells in Escherichia coli. MreB Perturbing Compound A22 hydrochloride is used for studies related to bacterial rod-shaped morphology determination, chromosome segregation, and cell division mechanisms .
Cat. No.: HY-142672
CAS No.: 2746446-99-9
ATR-IN-6 is a potent inhibitor of ATR. ATR is a class of protein kinases involved in genome stability and DNA damage repair, and is a member of the PIKK family. ATR-IN-6 has the potential for the research of ATR kinase-mediated diseases such as proliferative diseases and cancer (extracted from patent WO2021233376A1, compound A22) .
Cat. No.: HY-N13106
CAS No.: 60419-37-6
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Cat. No.: HY-155721
CAS No.: 1178895-15-2
Synonyms: 22-4′-Pyridinecarbonyl jorunnamycin A
22-(4′-py)-JA is a semisynthetic derivative of junamycin A (JA) that can be isolated from the Thai blue sponge (Xestospongia sp.). 22-(4′-py)-JA has antimetastatic activity and can inhibit AKT/mTOR/p70S6K signaling. 22-(4′-py)-JA inhibits tumor cell invasion and tube formation in human umbilical vein endothelial cells (HUVEC), downregulates metalloproteinases (MMP-2 and MMP-9), hypoxia-inducible factor 1α (HIF-1α) and vascular endothelial growth factor (VEGF). 22-(4′-py)-JA has potent anticancer activity against non-small cell lung cancer (NSCLC) .
Cat. No.: HY-RS13103
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SLC25A22 Human Pre-designed siRNA Set A contains three designed siRNAs for SLC25A22 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-CE00826
Synonyms: 22-Methylpentacosanoyl-coenzyme A
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22-Methylpentacosanoyl-CoA (22-Methylpentacosanoyl-coenzyme A) is a coenzyme A derivative.
Cat. No.: HY-CE00841
Synonyms: 22-Methyltricosanoyl-coenzyme A
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22-Methyltricosanoyl-CoA (22-Methyltricosanoyl-coenzyme A) is a coenzyme A derivative.
Cat. No.: HY-CE00839
Synonyms: 22-Methyltetracosanoyl-coenzyme A; Anteisopentacosanoyl-CoA; Anteisopentacosanoyl-coenzyme A
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22-Methyltetracosanoyl-CoA (22-Methyltetracosanoyl-coenzyme A) is a coenzyme A derivative.
Cat. No.: HY-CE01266
Synonyms: Coenzyme A(22:2(13Z,16Z))
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CoA(22:2(13Z,16Z)) (Coenzyme A(22:2(13Z,16Z))) is a coenzyme A derivative .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
