2746446-99-9
Chemical Structure
ATR-IN-6
- CAS No.: 2746446-99-9
- Formula:C28H28FN7O2
- Molecular Weight:513.57
IUPAC Name: (R)-(4-(4-(1-(5-fluoropyridin-3-yl)-3,5-dimethyl-1H-pyrazol-4-yl)-6-(3-methylmorpholino)pyrimidin-2-yl)-1H-indol-6-yl)methanol
InChIKey: BIDJUILZSVTDKU-MRXNPFEDSA-N
SMILES: OCC1=CC(C2=NC(N3[C@@H](COCC3)C)=CC(C4=C(N(C5=CN=CC(F)=C5)N=C4C)C)=N2)=C6C(NC=C6)=C1
Biological Activity: ATR-IN-6 is a potent inhibitor of ATR. ATR is a class of protein kinases involved in genome stability and DNA damage repair, and is a member of the PIKK family. ATR-IN-6 has the potential for the research of ATR kinase-mediated diseases such as proliferative diseases and cancer (extracted from patent WO2021233376A1, compound A22)[1].
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ATR-IN-6 | ATR-IN-6 is a potent inhibitor of ATR. ATR is a class of protein kinases involved in genome stability and DNA damage repair, and is a member of the PIKK family. ATR-IN-6 has the potential for the research of ATR kinase-mediated diseases such as proliferative diseases and cancer (extracted from patent WO2021233376A1, compound A22). | |||||||||||||||||||||
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Keywords