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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
12 Results for "
AA3
" in MedChemExpress (MCE) Product Catalog:
Products (12)
12 Results for "AA3" in MCE Product Catalog:
Cat. No.: HY-159700
CAS No.: 3027565-91-6
AA3-DLin is an ionizable cationic lipid with a pKa value of 5.8. AA3-DLin is used to delivery mRNA combined with lipid nanoparticles (LNPs). AA3-DLin LNP COVID-19 vaccines encapsulating SARS CoV-2 spike mRNAs successfully induces strong immunogenicity in a BALB/c mouse model .
Cat. No.: HY-W007584
CAS No.: 7314-44-5
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2,4-Dimethoxybenzyl alcohol, an aromatic alcohol, is a substrate of glucose-methanol-choline (GMC) oxidoreductase. GMC oxidoreductase displays the characteristics of an aryl-alcohol oxidase. 2,4-Dimethoxybenzyl alcohol can be used as a drug intermediate .
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MRE3008F20 is a highly efficient, highly selective and radioactive adenosine A3 receptor (AA3R) antagonist (Ki=1.8 nM). MRE3008F20 effectively antagonises Cl-IB-MECA-induced cAMP production in resting lymphocytes with an IC50 value of 5 nM. MRE3008F20 can be used in the study of AA3R .
Cat. No.: HY-172349
CAS No.: 2059985-55-4
JNJ-2901 is an inhibitor of M. tuberculosis cytochrome bc1:aa3. JNJ-2901 reduces bacterial load in the acute/chronic mouse infection models of M. tuberculosis H37Rv-ΔcydAB. JNJ-2901 can be used in tuberculosis (TB) research .
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Adenosine antagonist-1 is an adenosine A3 receptor (AA3R) antagonist with anti-inflammatory activity.
Cat. No.: HY-183075
CAS No.: 1648720-01-7
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ND-011458 is an Antibacterial agent, a QcrB inhibitor, and also an inhibitor of cytochrome bcc:aa3 oxidase function. ND-011458 binds to the QcrB subunit of cytochrome bcc:aa3 oxidase. ND-011458 inhibits ATP formation. When used in combination with Clofazimine (HY-B1046), ND-011458 exhibits bactericidal activity against Mycobacterium abscessus. ND-011458 can be used in studies related to Mycobacterium abscessus pulmonary infections .
Cat. No.: HY-147541
CAS No.: 1448221-36-0
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A2A/A3 AR antagonist-1 (compound 23) is a dual A2A/A3 adenosine receptor (AR) fluorescent ligand, with Kis of 90 nM and 31.8 nM for hA2A AR and hA3 AR, respectively .
Cat. No.: HY-RS19115
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Acy3 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Acy3 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-179681
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A2A/A3 agonist-1 is a dual A2A/A3 adenosine receptor agonist. A2A/A3 agonist-1 has a Ki value of 2.9 nM and an EC50 of 0.51 nM for hA2AAR. A2A/A3 agonist-1 has a Ki of 0.8 nM and an EC50 < 0.10 nM for hA3AR. A2A/A3 agonist-1 possesses anti-inflammatory activity and can be used for the research of inflammatory diseases .
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9-Cyclopentyladenine is an adenine derivative that binds to human AA1R, AA2AR, AA2BR and AA3R subtypes. 9-Cyclopentyladenine is used for the research of neurodegenerative diseases .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
