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AdV

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADC Antibody (2) Biochemical Assay Reagents (4) Cholinesterase (ChE) (1) CMV (3) DNA/RNA Synthesis (1) Drug Metabolite (1) E1/E2/E3 Enzyme (1) Enterovirus (1) Glutathione S-transferase (1) HPV (1) HSV (2) IFNAR (2) Influenza Virus (2) Interleukin Related (1) Isotope-Labeled Compounds (3) NF-κB (1) Orthopoxvirus (3) Parasite (1) RSV (1) STAT (1)
By Research Areas:	Cancer (2) Infection (13) Inflammation/Immunology (1) Neurological Disease (1)
Oligonucleotides:	Phospholipids (1)

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

Natural
Products

Isotope-Labeled Compounds

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-14532

Brincidofovir 5 Publications Verification CMX001; HDP-CDV	CMV HSV Orthopoxvirus	Infection
Brincidofovir (CMX001), the lipid-conjugated prodrug of Cidofovir (HY-17438), is an orally available, long-acting antiviral. Brincidofovir shows activity against a broad spectrum of DNA viruses including cytomegalovirus (CMV), adenovirus (ADV), varicella zoster virus, herpes simplex virus, polyomaviruses, papillomaviruses, poxviruses, and mixed double-stranded DNA virus infections. Brincidofovir, an oral antiviral in late stage development, has proven effective against orthopoxviruses in vitro and in vivo .

HY-Y0931

3-Iodobenzoic acid	Biochemical Assay Reagents	Infection
3-Iodobenzoic acid is a Monoiodobenzoic acid. 3-Iodobenzoic acid inhibits the *ADV7* virus. 3-Iodobenzoic acid can be used in the study of respiratory infections caused by ADV7 .

HY-114784

Ingavirin Ingamine	Influenza Virus	Infection
Ingavirin (Ingamine) exhibits broad spectrum antiviral activities against human respiratory viruses, such as influenza virus A (IVA), human parainfluenza virus (hPIV) and human adenovirus (AdV). Ingavirin exhibits no toxixcity to mice at the dose of 3000 mg/kg .

HY-P5694

Human α-defensin 5	HPV Parasite	Infection
Human α-defensin 5 is an antiviral peptide. Human α-defensin 5 blocks infection of non-enveloped viruses, including AdV, HPV, and polyomaviruses (IC₅₀: 0.6-1.25 μM for HPV16). Human α-defensin 5 can bind to the viral capsid and blocks escape of the virus from the endosome. Human α-defensin 5 increases HIV binding to the cell surface. Human α-defensin 5 also has parasiticidal activity .

HY-138956

MAY0132	NF-κB RSV	Infection
MAY0132 is a potent and selective EPAC2 inhibitor with an IC₅₀ of 0.4 μM. MAY0132 significantly inhibits replication of HMPV, *AdV* and RSV, reduces viral infection-induced cytokine/chemokine production, and inhibits NF-κB activation. MAY0132 has antiviral activity and can be used in the study of respiratory virus infection .

HY-14532S

Brincidofovir-d6 CMX001-d₆; HDP-CDV-d₆	Isotope-Labeled Compounds HSV CMV Orthopoxvirus	Infection
Brincidofovir-d₆ (CMX001-d₆) is the deuterium labeled Brincidofovir (HY-14532). Brincidofovir (CMX001), the lipid-conjugated prodrug of Cidofovir (HY-17438), is an orally available, long-acting antiviral. Brincidofovir shows activity against a broad spectrum of DNA viruses including cytomegalovirus (CMV), adenovirus (ADV), varicella zoster virus, herpes simplex virus, polyomaviruses, papillomaviruses, poxviruses, and mixed double-stranded DNA virus infections. Brincidofovir, an oral antiviral in late stage development, has proven effective against orthopoxviruses in vitro and in vivo. .

HY-131606S

Cidofovir diphosphate-13C3	Isotope-Labeled Compounds Orthopoxvirus Drug Metabolite CMV DNA/RNA Synthesis	Infection
Cidofovir diphosphate- ¹³C₃ is the ¹³C-labeled Cidofovir diphosphate (HY-131606). Cidofovir diphosphate is the intracellular active metabolite of Cidofovir (HY-17438) and its oral prodrug Brincidofovir (HY-14532). By inhibiting viral DNA polymerase (Ki ≈ 76.3 μM), cidofovir diphosphate is widely used in studies on double-stranded DNA virus infections, including cytomegalovirus (CMV), adenovirus (AdV), and poxviruses (such as monkeypox and molluscum contagiosum virus, MCV) .

HY-P992026

ADV-101 Antibody	ADC Antibody	Cancer
ADV-101 Antibody is a monoclonal antibody inhibitor targeting IL-1RAP. ADV-101 Antibody can be used to synthesize the antibody-drug conjugate (ADC) ADV-101. ADV-101 Antibody can be used to research related to cancer .

HY-Y0931S

3-Iodobenzoic Acid-13C6	Isotope-Labeled Compounds Biochemical Assay Reagents	Infection
3-Iodobenzoic Acid- ¹³C₆ is the ¹³C labeled 3-Iodobenzoic Acid (HY-Y0931). 3-Iodobenzoic acid is a Monoiodobenzoic acid. 3-Iodobenzoic acid inhibits the *ADV7* virus. 3-Iodobenzoic acid can be used in the study of respiratory infections caused by ADV7 .

HY-149900

Antiviral agent 33	Biochemical Assay Reagents	Infection
Antiviral agent 33 (compound 1c) is a double-stranded DNA (dsDNA) virus inhibitor with IC₅₀ values of 0.0790 and 0.1572 µM for VACV and AdV5, respectively. Antiviral agent 33 also has potential for oral administration .

HY-155823

TZ4M	Cholinesterase (ChE)	Neurological Disease
TZ4M is a 2,4-thiazolidinedione (TZD)-based anti-ADV agent with neuroprotective effects. TZ4M exhibits AChE inhibition in human plasma. TZ4M improves memory and cognitive impairment in adult rats in a scopolamine (HY-N0296)-induced Alzheimer-type model .

HY-180378

3-Iodobenzoate sodium	Biochemical Assay Reagents	Infection
3-Iodobenzoate sodium is a Monoiodobenzoic acid. 3-Iodobenzoate sodium inhibits the *ADV7* virus. 3-Iodobenzoate sodium can be used in the study of respiratory infections caused by ADV7 .

HY-P992027

CSC012 Antibidy	ADC Antibody	Cancer
CSC012 Antibody is a monoclonal antibody inhibitor targeting IL-1RAP. CSC012 Antibody can be used to synthesize the antibody-drug conjugate (ADC) CSC012. ADV-101 Antibody can be used to research related to acute myeloid leukemia .

HY-181603

Antiviral agent 79	Enterovirus IFNAR	Infection
Antiviral agent 79 is a broad-spectrum antiviral agent. Antiviral agent 79 exhibits anti-EV71, anti-CVB3 and anti-ADV7 activities. Antiviral agent 79 activates the host type I interferon signaling pathway to enhance antiviral defense. Antiviral agent 79 can be used in research related to viral infections .

HY-180548

MRC37	E1/E2/E3 Enzyme	Infection Inflammation/Immunology
MRC37 is a potent and selective small-molecule ligand of TRIM21 that binds the PRYSPRY domain of TRIM21. MRC37 inhibits the natural antiviral function of TRIM21 by preventing antibody neutralisation of adenovirus 5 (Adv5). MRC37 is also capable of inhibiting Trim-Away, a targeted protein degradation technology where TRIM21 is recruited to specific proteins via electroporated antibodies .

HY-N17963

Cappariloside A	Glutathione S-transferase Influenza Virus Interleukin Related IFNAR STAT	Infection
Cappariloside A is a larvicide that exhibits larvicidal activity against Aedes aegypti larvae and reduces larval glutathione-S-transferase activity. Cappariloside A also possesses antiviral activity, decreases the level of phosphorylated STAT1 in cells, inhibits the replication of influenza viruses H1N1, H3N2, PIV3 and *ADV, and downregulates the expression of IL-6, IP-10, MIG, RANTES/CCL-5, IFN-β* and IL-29. Cappariloside A suppresses the inflammatory response induced by mouse lung-adapted influenza virus strains. Cappariloside A can be used in studies related to larvicidal applications and influenza virus infection .

3-Iodobenzoic acid	Biochemical Assay Reagents
3-Iodobenzoic acid is a Monoiodobenzoic acid. 3-Iodobenzoic acid inhibits the *ADV7* virus. 3-Iodobenzoic acid can be used in the study of respiratory infections caused by ADV7 .

Cat. No.	Product Name	Target	Research Area

HY-P5694

Human α-defensin 5	HPV Parasite	Infection
Human α-defensin 5 is an antiviral peptide. Human α-defensin 5 blocks infection of non-enveloped viruses, including AdV, HPV, and polyomaviruses (IC₅₀: 0.6-1.25 μM for HPV16). Human α-defensin 5 can bind to the viral capsid and blocks escape of the virus from the endosome. Human α-defensin 5 increases HIV binding to the cell surface. Human α-defensin 5 also has parasiticidal activity .

Cat. No.	Product Name	Target	Research Area	Image

HY-P992026

ADV-101 Antibody	ADC Antibody	Cancer
ADV-101 Antibody is a monoclonal antibody inhibitor targeting IL-1RAP. ADV-101 Antibody can be used to synthesize the antibody-drug conjugate (ADC) ADV-101. ADV-101 Antibody can be used to research related to cancer .

HY-P992027

CSC012 Antibidy	ADC Antibody	Cancer
CSC012 Antibody is a monoclonal antibody inhibitor targeting IL-1RAP. CSC012 Antibody can be used to synthesize the antibody-drug conjugate (ADC) CSC012. ADV-101 Antibody can be used to research related to acute myeloid leukemia .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N17963

Cappariloside A	Structural Classification Alkaloids Capparaceae Plants Maerua siamensis (Kurz) Pax Indole Alkaloids Source Classification	Glutathione S-transferase Influenza Virus Interleukin Related IFNAR STAT
Cappariloside A is a larvicide that exhibits larvicidal activity against Aedes aegypti larvae and reduces larval glutathione-S-transferase activity. Cappariloside A also possesses antiviral activity, decreases the level of phosphorylated STAT1 in cells, inhibits the replication of influenza viruses H1N1, H3N2, PIV3 and *ADV, and downregulates the expression of IL-6, IP-10, MIG, RANTES/CCL-5, IFN-β* and IL-29. Cappariloside A suppresses the inflammatory response induced by mouse lung-adapted influenza virus strains. Cappariloside A can be used in studies related to larvicidal applications and influenza virus infection .

Cat. No.	Product Name	Chemical Structure

HY-14532S

Brincidofovir-d6
Brincidofovir-d₆ (CMX001-d₆) is the deuterium labeled Brincidofovir (HY-14532). Brincidofovir (CMX001), the lipid-conjugated prodrug of Cidofovir (HY-17438), is an orally available, long-acting antiviral. Brincidofovir shows activity against a broad spectrum of DNA viruses including cytomegalovirus (CMV), adenovirus (ADV), varicella zoster virus, herpes simplex virus, polyomaviruses, papillomaviruses, poxviruses, and mixed double-stranded DNA virus infections. Brincidofovir, an oral antiviral in late stage development, has proven effective against orthopoxviruses in vitro and in vivo. .

Brincidofovir-d6

Brincidofovir-d₆ (CMX001-d₆) is the deuterium labeled Brincidofovir (HY-14532). Brincidofovir (CMX001), the lipid-conjugated prodrug of Cidofovir (HY-17438), is an orally available, long-acting antiviral. Brincidofovir shows activity against a broad spectrum of DNA viruses including cytomegalovirus (CMV), adenovirus (ADV), varicella zoster virus, herpes simplex virus, polyomaviruses, papillomaviruses, poxviruses, and mixed double-stranded DNA virus infections. Brincidofovir, an oral antiviral in late stage development, has proven effective against orthopoxviruses in vitro and in vivo. .

HY-131606S

Cidofovir diphosphate-13C3
Cidofovir diphosphate- ¹³C₃ is the ¹³C-labeled Cidofovir diphosphate (HY-131606). Cidofovir diphosphate is the intracellular active metabolite of Cidofovir (HY-17438) and its oral prodrug Brincidofovir (HY-14532). By inhibiting viral DNA polymerase (Ki ≈ 76.3 μM), cidofovir diphosphate is widely used in studies on double-stranded DNA virus infections, including cytomegalovirus (CMV), adenovirus (AdV), and poxviruses (such as monkeypox and molluscum contagiosum virus, MCV) .

Cidofovir diphosphate-13C3

Cidofovir diphosphate- ¹³C₃ is the ¹³C-labeled Cidofovir diphosphate (HY-131606). Cidofovir diphosphate is the intracellular active metabolite of Cidofovir (HY-17438) and its oral prodrug Brincidofovir (HY-14532). By inhibiting viral DNA polymerase (Ki ≈ 76.3 μM), cidofovir diphosphate is widely used in studies on double-stranded DNA virus infections, including cytomegalovirus (CMV), adenovirus (AdV), and poxviruses (such as monkeypox and molluscum contagiosum virus, MCV) .

HY-Y0931S

3-Iodobenzoic Acid-13C6
3-Iodobenzoic Acid- ¹³C₆ is the ¹³C labeled 3-Iodobenzoic Acid (HY-Y0931). 3-Iodobenzoic acid is a Monoiodobenzoic acid. 3-Iodobenzoic acid inhibits the *ADV7* virus. 3-Iodobenzoic acid can be used in the study of respiratory infections caused by ADV7 .

Cat. No.	Product Name		Classification

HY-14532

Brincidofovir 5 Publications Verification CMX001; HDP-CDV		Phospholipids
Brincidofovir (CMX001), the lipid-conjugated prodrug of Cidofovir (HY-17438), is an orally available, long-acting antiviral. Brincidofovir shows activity against a broad spectrum of DNA viruses including cytomegalovirus (CMV), adenovirus (ADV), varicella zoster virus, herpes simplex virus, polyomaviruses, papillomaviruses, poxviruses, and mixed double-stranded DNA virus infections. Brincidofovir, an oral antiviral in late stage development, has proven effective against orthopoxviruses in vitro and in vivo .

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AdV

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

NaturalProducts

Isotope-Labeled Compounds

Oligonucleotides

Natural
Products