229483-41-4
Chemical Structure
Cappariloside A
- CAS No.: 229483-41-4
- Formula:C16H18N2O6
- Molecular Weight:334.32
InChIKey: ZVFUTZQNUQUJLW-YMILTQATSA-N
SMILES: N#CCC1=CNC2=CC=CC(O[C@@H]3O[C@@H]([C@H]([C@@H]([C@H]3O)O)O)CO)=C21
Biological Activity: Cappariloside A is a larvicide that exhibits larvicidal activity against Aedes aegypti larvae and reduces larval glutathione-S-transferase activity. Cappariloside A also possesses antiviral activity, decreases the level of phosphorylated STAT1 in cells, inhibits the replication of influenza viruses H1N1, H3N2, PIV3 and ADV, and downregulates the expression of IL-6, IP-10, MIG, RANTES/CCL-5, IFN-β and IL-29. Cappariloside A suppresses the inflammatory response induced by mouse lung-adapted influenza virus strains. Cappariloside A can be used in studies related to larvicidal applications and influenza virus infection[1][2].
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Cappariloside A | Cappariloside A is a larvicide that exhibits larvicidal activity against Aedes aegypti larvae and reduces larval glutathione-S-transferase activity. Cappariloside A also possesses antiviral activity, decreases the level of phosphorylated STAT1 in cells, inhibits the replication of influenza viruses H1N1, H3N2, PIV3 and ADV, and downregulates the expression of IL-6, IP-10, MIG, RANTES/CCL-5, IFN-β and IL-29. Cappariloside A suppresses the inflammatory response induced by mouse lung-adapted influenza virus strains. Cappariloside A can be used in studies related to larvicidal applications and influenza virus infection. | |||||||||||||||||||||
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[1]. Saksit Nobsathian, et al. Larvicidal effect of compounds isolated
from Maerua siamensis (Capparidaceae)
against Aedes aegypti (Diptera: Culicidae) larvae. Chem. Biol. Technol. Agric. 5, 8 (2018). - [2]. Li Z, et al. Cappariloside A shows antiviral and better anti-inflammatory effects against influenza virus via regulating host IFN signaling, in vitro and vivo. Life Sci. 2018;200:115-125. [Content Brief]
Keywords
