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Cat. No.: HY-P5694

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Human α-defensin 5

1 Cited Publications

Customer Review

Based on 1 publication(s) in Google Scholar

Human α-defensin 5 is an antiviral peptide. Human α-defensin 5 blocks infection of non-enveloped viruses, including AdV, HPV, and polyomaviruses (IC₅₀: 0.6-1.25 μM for HPV16). Human α-defensin 5 can bind to the viral capsid and blocks escape of the virus from the endosome. Human α-defensin 5 increases HIV binding to the cell surface. Human α-defensin 5 also has parasiticidal activity.

For research use only. We do not sell to patients.

Formula: C₁₄₄H₂₃₈N₅₀O₄₅S₆
Molecular Weight:3582.13

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Please store the product under the recommended conditions in the Certificate of Analysis.

Human α-defensin 5 Chemical Structure

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

All Parasite Isoforms :

Chemical Information

Molecular Weight 3582.13
Formula C₁₄₄H₂₃₈N₅₀O₄₅S₆
Sequence

Ala-Thr-Cys-Tyr-Cys-Arg-Thr-Gly-Arg-Cys-Ala-Thr-Arg-Glu-Ser-Leu-Ser-Gly-Val-Cys-Glu-Ile-Ser-Gly-Arg-Leu-Tyr-Arg-Leu-Cys-Cys-Arg (Disulfide bridge:Cys3-Cys31,Cys5-Cys20,Cys10-Cys30)
Sequence Shortening

ATCYCRTGRCATRESLSGVCEISGRLYRLCCR (Disulfide bridge:Cys3-Cys31,Cys5-Cys20,Cys10-Cys30)
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.

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Imeta

2026 Feb 19.

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Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (260 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Gounder AP, et al. Critical determinants of human α-defensin 5 activity against non-enveloped viruses. J Biol Chem. 2012 Jul 13;287(29):24554-62. [Content Brief]

[2]. Tanaka T, et al. Parasiticidal activity of human alpha-defensin-5 against Toxoplasma gondii. In Vitro Cell Dev Biol Anim. 2010 Jun;46(6):560-5. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Human α-defensin 5

1 Cited Publications

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Biological Activity
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Human α-defensin 5

Publications Citing Use of MedChemExpress (MCE) Human α-defensin 5

All Parasite Isoforms

Biological Activity

Chemical Information

Publications (1)

Purity & Documentation

References

Calculators

Help & FAQs

Human α-defensin 5 Related Classifications

HY-P5694 Related Classifications