Human α-defensin 5
Based on 1 publication(s) in Google Scholar
Human α-defensin 5 is an antiviral peptide. Human α-defensin 5 blocks infection of non-enveloped viruses, including AdV, HPV, and polyomaviruses (IC50: 0.6-1.25 μM for HPV16). Human α-defensin 5 can bind to the viral capsid and blocks escape of the virus from the endosome. Human α-defensin 5 increases HIV binding to the cell surface. Human α-defensin 5 also has parasiticidal activity.
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- Formule: C144H238N50O45S6
- Masse moléculaire:3582.13
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Publications Citing Use of MedChemExpress (MCE) Human α-defensin 5
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Activité biologique
Chemical Information
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Masse moléculaire 3582.13
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Formule C144H238N50O45S6
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Sequence
Ala-Thr-Cys-Tyr-Cys-Arg-Thr-Gly-Arg-Cys-Ala-Thr-Arg-Glu-Ser-Leu-Ser-Gly-Val-Cys-Glu-Ile-Ser-Gly-Arg-Leu-Tyr-Arg-Leu-Cys-Cys-Arg (Disulfide bridge:Cys3-Cys31,Cys5-Cys20,Cys10-Cys30)
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Sequence Shortening
ATCYCRTGRCATRESLSGVCEISGRLYRLCCR (Disulfide bridge:Cys3-Cys31,Cys5-Cys20,Cys10-Cys30)
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (1)
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Journal Impact Factor
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Most Recent
Pureté et documentation
Références
[1]. Gounder AP, et al. Critical determinants of human α-defensin 5 activity against non-enveloped viruses. J Biol Chem. 2012 Jul 13;287(29):24554-62. [Content Brief]
[2]. Tanaka T, et al. Parasiticidal activity of human alpha-defensin-5 against Toxoplasma gondii. In Vitro Cell Dev Biol Anim. 2010 Jun;46(6):560-5. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Human α-defensin 5 Related Classifications
HY-P5694 Related Classifications
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