1 Result for "

Ananxyl

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Ananxyl" in MCE Product Catalog:

Cat. No.: HY-W013150
CAS No.: 82626-01-5
Target:  

GABA Receptor

Research Areas:  

Neurological Disease

Alpidem, an anxiolytic agent, is an orally active and brain-penetrant GABAA receptor ligand, binds to α1β2γ2 subunit-containing GABAA receptors (IC50 of 17 nM) over α5β2γ2 subunit-containing GABAA receptors (IC50 of >10 μM). Alpidem modulates calcium-induced mitochondrial permeability transition, induces glutathione depletion and hepatocyte necrosis, potentiates TNF-α toxicity, inhibits marble-burying and locomotor activity, enhances stressed rodent feeding behavior, and exerts anticonvulsant effects. Alpidem can be used for the research of anxiety, anxiety disorders, and convulsions .
loading...
    loading...