42 Results for "

B0141

" in MedChemExpress (MCE) Product Catalog:
Products (42)

42 Results for "B0141" in MCE Product Catalog:

136
136 Publications Verification
Cat. No.: HY-B0141
CAS No.: 50-28-2
Synonyms: β-Estradiol; E2; 17β-Estradiol; 17β-Oestradiol
Estradiol (β-Estradiol) is a steroid hormone and the major female sex hormone. Estradiol can up-regulate the expression of neural markers of human endometrial stem cells (hEnSCs) and promote their neural differentiation. Estradiol can be used for the research of cancers, neurodegenerative diseases and neural tissue engineering .
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136
136 Publications Verification
Cat. No.: HY-B0141C
CAS No.: 35380-71-3
Synonyms: β-Estradiol hemihydrate; 17β-Estradiol hemihydrate; 17β-Oestradiol hemihydrate
Estradiol (β-Estradiol) hemihydrate is a steroid hormone and the major female sex hormone. Estradiol (β-Estradiol) hemihydrate can up-regulate the expression of neural markers of human endometrial stem cells (hEnSCs) and promote their neural differentiation. Estradiol (β-Estradiol) hemihydrate can be used for the research of cancers, neurodegenerative diseases and neural tissue engineering .
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3
3 Cited Publications
Cat. No.: HY-B0141S1
CAS No.: 66789-03-5
Synonyms: β-Estradiol-d4; 17β-Estradiol-d4; 17β-Oestradiol-d4
Estradiol-d4 is the deuterium labeled Estradiol. Estradiol is a steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females. Estradiol upregulates IL-6 expression through the estrogen receptor β (ERβ) pathway .
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3
3 Cited Publications
Cat. No.: HY-113293B
CAS No.: 438-67-5
Purity:  99.84%
Estrone sulfate sodium is an inactive endogenous estrogen that can be converted into Estrone (HY-B0234) and Estradiol (HY-B0141). Estrone sulfate sodium is also a substrate of the OATP1B3 transporter. Estrone sulfate sodium can be converted into Estrone and Estradiol in normal mammary parenchymal cells. Estrone sulfate sodium stimulates the growth of nitrosomethylurea-induced mammary tumors in ovariectomized rats and the colony formation of dispersed nitrosomethylurea mammary cells, with conversion into Estrone and Estradiol occurring both in vivo and in vitro during this process. Estrone sulfate sodium is applicable to breast cancer-related research .
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3
3 Cited Publications
Cat. No.: HY-113293A
CAS No.: 1240-04-6
Purity:  99.45%
Estrone sulfate potassium is an inactive endogenous estrogen that can be converted into Estrone (HY-B0234) and Estradiol (HY-B0141). Estrone sulfate potassium is also a substrate of the OATP1B3 transporter. Estrone sulfate potassium can be converted into Estrone and Estradiol in normal mammary parenchymal cells. Estrone sulfate potassium stimulates the growth of nitrosomethylurea-induced mammary tumors in ovariectomized rats and the colony formation of dispersed nitrosomethylurea mammary cells, with conversion into Estrone and Estradiol occurring both in vivo and in vitro during this process. Estrone sulfate potassium is applicable to breast cancer-related research .
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1
1 Cited Publications
Cat. No.: HY-B0141A
CAS No.: 57-91-0
Synonyms: Alfatradiol; Epiestradiol; Epiestrol
Alpha-Estradiol is a weak estrogen and a 5α-reductase inhibitor which is used as a topical medication in the treatment of androgenic alopecia.
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1
1 Cited Publications
Cat. No.: HY-B0141R
CAS No.: 50-28-2
Synonyms: β-Estradiol (Standard); E2 (Standard); 17β-Estradiol (Standard); 17β-Oestradiol (Standard)
Estradiol (Standard) is the analytical standard of Estradiol. This product is intended for research and analytical applications. Estradiol (β-Estradiol) is a steroid hormone and the major female sex hormone. Estradiol can up-regulate the expression of neural markers of human endometrial stem cells (hEnSCs) and promote their neural differentiation. Estradiol can be used for the research of cancers, neurodegenerative diseases and neural tissue engineering .
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1
1 Cited Publications
Cat. No.: HY-N7755
CAS No.: 14982-12-8
Estradiol 3-glucuronide sodium is an estrogen metabolite, which is a glucuronide conjugate formed by the catalysis of uridine diphosphate glucuronosyltransferase in tissues such as the liver from Estradiol (HY-B0141). Estradiol 3-glucuronide sodium is a potent substrate of Mrp2, with an S50 of 55.7 μM. Estradiol 3-glucuronide sodium achieves hepatobiliary transport in hepatocytes through basolateral uptake via OATP1B1, OATP1B3 and OATP2B1, as well as apical efflux via MRP2 and BCRP .
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1
1 Cited Publications
Cat. No.: HY-N10403
CAS No.: 5976-61-4
Synonyms: 4-Hydroxy-17β-estradiol
4-Hydroxyestradiol (4-Hydroxy-17β-estradiol) is an endogenous metabolite of Estradiol (HY-B0141). 4-Hydroxyestradiol is carcinogenic and shows mutagenic activity in breast epithelial cells. 4-Hydroxyestradiol inhibits the binding of Estradiol to the estrogen receptor in a competitive manner, with a Ki of 0.48 nM .
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1
1 Cited Publications
Cat. No.: HY-W585842
CAS No.: 15270-30-1
Estradiol 3-glucuronide is an estrogen metabolite, which is a glucuronide conjugate formed from Estradiol (HY-B0141) via catalysis by uridine diphosphate glucuronosyltransferases in tissues such as the liver. Estradiol 3-glucuronide is a potent substrate of Mrp2, with an S50 value of 55.7 μM. Estradiol 3-glucuronide achieves hepatobiliary transport in hepatocytes through basolateral uptake via OATP1B1, OATP1B3 and OATP2B1, as well as apical efflux via MRP2 and BCRP .
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1
1 Cited Publications
Cat. No.: HY-161541
Estradiol/BSA is the antigen-adjuvant conjugate formed by the coupling of Estradiol (HY-B0141) with Bovine Serum Albumin (BSA). By coupling the antigen with a protein adjuvant, the production of antigen-specific antibodies in vaccine models can be enhanced. The conjugate does not affect protein folding or disrupt major epitopes, and it can enhance cross-presentation and the generation of antigen-specific T cells.
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Cat. No.: HY-B0141S2
CAS No.: 221093-45-4
Synonyms: β-Estradiol-d5; 17β-Estradiol-d5; 17β-Oestradiol-d5
Estradiol-d5 is deuterium labeled Estradiol. Estradiol is a steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females. Estradiol upregulates IL-6 expression through the estrogen receptor β (ERβ) pathway .
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Cat. No.: HY-B0141S
CAS No.: 79037-37-9
Synonyms: β-Estradiol-d3; 17β-Estradiol-d3; 17β-Oestradiol-d3
Estradiol-d3 is the deuterium labeled Estradiol. Estradiol is a steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females. Estradiol upregulates IL-6 expression through the estrogen receptor β (ERβ) pathway.
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Cat. No.: HY-B0141AR
CAS No.: 57-91-0
Synonyms: Alfatradiol(Standard); Epiestradiol(Standard); Epiestrol (Standard)
Alpha-Estradiol (Standard) is the analytical standard of Alpha-Estradiol. This product is intended for research and analytical applications. Alpha-Estradiol is a weak estrogen and a 5α-reductase inhibitor which is used as a topical medication in the treatment of androgenic alopecia.
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Cat. No.: HY-B0141S3
CAS No.: 53866-33-4
Synonyms: β-Estradiol-d2; 17β-Estradiol-d2; 17β-Oestradiol-d2
Estradiol-d2 is the deuterium labeled Estradiol. Estradiol is a steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females. Estradiol upregulates IL-6 expression through the estrogen receptor β (ERβ) pathway .
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Cat. No.: HY-B0141S5
CAS No.: 82938-05-4
Synonyms: β-Estradiol-13C2; E2-13C2; 17β-Estradiol-13C2; 17β-Oestradiol-13C2
Estradiol- 13C2 is the 13C-labeled Estradiol. Estradiol is a steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females. Estradiol upregulates IL-6 expression through the estrogen receptor β (ERβ) pathway .
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Cat. No.: HY-B0141B
CAS No.: 28014-46-2
Synonyms: Polyestrol phosphate
Target:  

Drug Derivative

Research Areas:  

Cancer

Polyestradiol phosphate (Polyestrol phosphate) is a polymer of Estradiol (HY-B0141) and Phosphoric acid. Polyestradiol phosphate can be used in the research of prostate cancer .
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Cat. No.: HY-B0141S4
Synonyms: β-Estradiol-13C6; E2-13C6; 17β-Estradiol-13C6; 17β-Oestradiol-13C6
Estradiol- 13C6 is the 13C-labeled Estradiol. Estradiol is a steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females. Estradiol upregulates IL-6 expression through the estrogen receptor β (ERβ) pathway .
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Cat. No.: HY-B0141E
CAS No.: 3736-22-9
Synonyms: ent-β-Estradiol; ent-17β-Estradiol; ent-17β-Oestradiol
Target:  

Estrogen Receptor/ERR

Research Areas:  

Endocrinology

Ent-Estradiol is the enantiomer of Estradiol (HY-B0141). Ent-Estradiol is a highly selective estrogen receptor ligand, but does not possess estrogenic activity. Ent-Estradiol displays IC50 values of 24.9 nM, 9.59 nM and 8.17 nM for human, rat and mouse ERβ, and 151 nM, 246 nM and 268 nM for human, rat and mouse ERα, respectively. Ent-Estradiol can be used for the study of menopausal physiological changes .
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Cat. No.: HY-B0141S6
CAS No.: 3188-46-3
Synonyms: β-Estradiol-d2-1; E2-d2-1; 17β-Estradiol-d2-1; 17β-Oestradiol-d2-1
Estradiol-d2-1 is the deuterium labeled Estradiol. Estradiol is a steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females. Estradiol upregulates IL-6 expression through the estrogen receptor β (ERβ) pathway .
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