22 Results for "

B2167

" in MedChemExpress (MCE) Product Catalog:
Products (22)

22 Results for "B2167" in MCE Product Catalog:

50
50 Cited Publications
Cat. No.: HY-B2167
CAS No.: 6217-54-5
Synonyms: DHA; Cervonic acid
Docosahexaenoic Acid (DHA) is an omega-3 fatty acid abundantly present brain and retina. It can be obtained directly from fish oil and maternal milk.
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1
1 Cited Publications
Cat. No.: HY-130289
CAS No.: 90906-40-4
Synonyms: 4-Hydroxy docosahexaenoic acid; (±)4-HDoHE
Target:  

PPAR

(±)4-HDHA (4-Hydroxy docosahexaenoic acid) is an autoxidation product of Docosahexaenoic acid (HY-B2167) (DHA). (±)4-HDHA is a PPARγ agonist, antidiabetic and anti-inflammatory agent .
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Cat. No.: HY-B2167R
CAS No.: 6217-54-5
Synonyms: DHA (Standard); Cervonic acid (Standard)
Docosahexaenoic acid (Standard) is the analytical standard of Docosahexaenoic acid. This product is intended for research and analytical applications. Docosahexaenoic Acid (DHA) is an omega-3 fatty acid abundantly present brain and retina. It can be obtained directly from fish oil and maternal milk. In Vitro: Docosahexaenoic acid (DHA) is essential for the growth and functional development of the brain in infants. DHA is also required for maintenance of normal brain function in adults. The inclusion of plentiful DHA in the diet improves learning ability and memory . DHA is an essential requirement in every step of brain development like neural cell proliferation, migration, differentiation, synaptogenesis. The multiple double bonds and unique structure allow DHA to impart special membrane characteristics for effective cell signaling. Many development disorders like dyslexia, autism spectrum disorder, attention deficit hyperactivity disorder, schizophrenia etc. are causally related to decreased level of DHA . DHA is a potent RXR ligand inducing robust RXR activation already at low micro molar concentrations. The EC50 for RXRα activation by DHA is about 5-10 μM fatty acid . In Vivo: Docosahexaenoic acid administration over 10 weeks significantly reduces the number of reference memory errors, without affecting the number of working memory errors, and significantly increases the docosahexaenoic acid content and the docosahexaenoic acid/arachidonic acid ratio in both the hippocampus and the cerebral cortex . DHA treatment exerts neuroprotective actions on an experimental mouse model of PD. There is a decrease tendency in brain lipid oxidation of MPTP mice but it does not significantly .
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Cat. No.: HY-B2167S
CAS No.: 1197205-71-2
Synonyms: DHA-d5; Cervonic acid-d5
Docosahexaenoic acid-d5 is the deuterium labeled Docosahexaenoic Acid. Docosahexaenoic Acid (DHA) is an omega-3 fatty acid abundantly present brain and retina. It can be obtained directly from fish oil and maternal milk.
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Cat. No.: HY-B2167S2
Docosahexaenoic acid- 13C4 is 13C labeled Docosahexaenoic acid. Docosahexaenoic Acid (DHA) is an omega-3 fatty acid abundantly present brain and retina. It can be obtained directly from fish oil and maternal milk .
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Cat. No.: HY-120442
CAS No.: 1345275-27-5
Target:  

COX

Research Areas:  

Cardiovascular Disease

(±)16(17)-DiHDPA is a epoxygenase metabolite of docosahexaenoic acid (HY-B2167). (±)16(17)-DiHDPA inhibits platelet aggregation at concentrations below those affecting thromboxane synthesis .
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Cat. No.: HY-172548
Docosahexaenoyl-L-carnitine chloride is a long-chain acylcarnitine composed of Docosahexaenoic acid (HY-B2167) and L-carnitine (HY-B0399). Docosahexaenoyl-L-carnitine chloride is transported into mitochondria for β -oxidation and decomposition under the action of carnitine palmitoyltransferase I (CPT I) and others. Docosahexaenoyl-L-carnitine chloride is promising for research of diseases related to fatty acid metabolism .
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Cat. No.: HY-120178
CAS No.: 168111-93-1
Purity:  98.0%
(±)7(8)-DiHDPA is a epoxygenase metabolite of docosahexaenoic acid (HY-B2167). (±)7(8)-DiHDPA inhibits platelet aggregation at concentrations below those affecting thromboxane synthesis .
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Cat. No.: HY-158594
CAS No.: 2692622-57-2
Synonyms: DHA-alkyne; FA 22:8
Target:  

Drug Derivative

Research Areas:  

Others

Docosahexaenoic acid alkyne (FA 22:8) is the ω-alkyne derivative of Docosahexaenoic acid (HY-B2167) .
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Cat. No.: HY-157690
CAS No.: 2460392-58-7
Target:  

Drug Metabolite

Research Areas:  

Others

19(S),20(R)-EDP is an epoxidized metabolite of docosahexaenoic acid (HY-B2167) .
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Cat. No.: HY-120312
CAS No.: 1810710-69-0
Target:  

Drug Derivative

Research Areas:  

Others

PCTR3 is a Docosahexaenoic acid DHA (HY-B2167) derivative, which acts as a pro-resolving and tissue regeneration lipid mediator .
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Cat. No.: HY-158623
CAS No.: 1345275-24-2
Synonyms: (±)13,14-DiHDPE
(±)13(14)-DiHDPA ((±)13,14-DiHDPE) a metabolite of Docosahexaenoic acid (DHA; HY-B2167) by P450 (CYP) metabolic pathways .
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Cat. No.: HY-19886
CAS No.: 92510-91-3
Target:  

Drug Intermediate

Research Areas:  

Cardiovascular Disease

F 16915, a Docosahexaenoic Acid (DHA, HY-B2167) derivative, is a potent pro-agent of DHA. F 16915 can prevent heart failure-induced atrial fibrillation .
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Cat. No.: HY-157690A
CAS No.: 2242542-60-3
Target:  

Drug Metabolite

Research Areas:  

Others

19(R),20(S)-EDP (compound 19(S),20(R)-2a) is an oxylipin and a metabolite of docosahexaenoic acid (HY-B2167) .
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Cat. No.: HY-142974
CAS No.: 116198-39-1
Synonyms: 1,2-Olein-3-Docosohexaenoin; 18:1/18:1/22:6-TG; C1OO
Target:  

Endogenous Metabolite

Research Areas:  

Metabolic Disease

1,2-Dioleoyl-3-docosohexaenoyl-rac-glycerol is a triacylglycerol that contains oleic acid (HY-N1446) at the sn-1 and sn-2 positions and docosahexaenoic acid (HY-B2167) at the sn-3 position. It has been detected in human breast milk.
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Cat. No.: HY-W708469
CAS No.: 810668-53-2
Resolvin D2 methyl ester is an ester derivative of the DHA (HY-B2167) metabolite Resolvin D2 (HY-121636) with anti-inflammatory and anti-infective activities. Resolvin D2 is a leukocyte modulator and a potent inhibitor of neuronal TRPV1 (IC50=0.1 nM) and TRPA1 (IC50=2 nM). Resolvin D2 can be used in sepsis research .
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Cat. No.: HY-134997
CAS No.: 845673-74-7
Synonyms: 4-oxo DHA
Target:  

PPAR

Research Areas:  

Cancer

4-oxo Docosahexaenoic acid (4-oxo DHA) is a putative metabolite of Docosahexaenoic acid (HY-B2167) with antiproliferative and PPARγ agonist activity. It inhibits the growth of several triple negative breast cancer cell lines (MCF-10F, trMCF, bsMCF, MDA-MB-231, and BT549) at 50-100 μM, however it increased proliferation of MCF-7 cells. 4-oxo DHA binds covalently to PPARγ and activates gene transcription in luciferase reporter assays and in dendritic cells with EC50 values of approximately 8-16 μM.
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Cat. No.: HY-116115
CAS No.: 1233715-33-7
Synonyms: 17-Oxo-DPA; 17-Oxo-7(Z),10(Z),13(Z),15(E),19(Z)-DPA
Target:  

NF-κB PPAR

Research Areas:  

Inflammation/Immunology

17-Oxo-7(Z),10(Z),13(Z),15(E),19(Z)-docosapentaenoic acid (17-Oxo-DPA; 17-Oxo-7(Z),10(Z),13(Z),15(E),19(Z)-DPA) is an electrophilic oxo-derivative (EFOX) of the docosahexaenoic acid (DHA) (HY-B2167). 17-Oxo-7(Z),10(Z),13(Z),15(E),19(Z)-docosapentaenoic acid is generated during inflammation by COX-2-catalyzed mechanism in activated macrophages. 17-Oxo-7(Z),10(Z),13(Z),15(E),19(Z)-docosapentaenoic acid acts as an agonist for PPARγ and a modulator for NF-κB signaling pathway, inhibits the production of pro-inflammatory cytokines and nitric oxide, and exhibits anti-inflammatory efficacy .
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Cat. No.: HY-170676
CAS No.: 157363-75-2
Research Areas:  

Metabolic Disease

1,3-Dilinoleoyl-2-docosahexaenoyl glycerol is a triacylglycerol that contains Linoleic acid (HY-N0729) at the sn-1 and sn-3 positions and Docosahexaenoic acid (HY-B2167) at the sn-2 position.
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Cat. No.: HY-168783
CAS No.: 77388-16-0
Target:  

Drug Derivative

Research Areas:  

Others

7(Z),10(Z),13(Z)-Hexadecatrienoic acid methyl ester is a polyunsaturated fatty acid generated during the synthesis of Docosahexaenoic acid-d5 (HY-B2167S) .
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