2. Search Result
Search Result
Results for "

B2167

" in MedChemExpress (MCE) Product Catalog:

20

Inhibitors & Agonists

4

Natural
Products

2

Isotope-Labeled Compounds

1

Click Chemistry

1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B2167
    Docosahexaenoic acid
    45+ Cited Publications

    DHA; Cervonic acid

    		 Endogenous Metabolite Neurological Disease Cancer
    Docosahexaenoic Acid (DHA) is an omega-3 fatty acid abundantly present brain and retina. It can be obtained directly from fish oil and maternal milk.
    Docosahexaenoic acid
  • HY-B2167R
    Docosahexaenoic acid (Standard)

    DHA (Standard); Cervonic acid (Standard)

    		 Reference Standards Endogenous Metabolite Neurological Disease Cancer
    Docosahexaenoic acid (Standard) is the analytical standard of Docosahexaenoic acid. This product is intended for research and analytical applications. Docosahexaenoic Acid (DHA) is an omega-3 fatty acid abundantly present brain and retina. It can be obtained directly from fish oil and maternal milk. In Vitro: Docosahexaenoic acid (DHA) is essential for the growth and functional development of the brain in infants. DHA is also required for maintenance of normal brain function in adults. The inclusion of plentiful DHA in the diet improves learning ability and memory . DHA is an essential requirement in every step of brain development like neural cell proliferation, migration, differentiation, synaptogenesis. The multiple double bonds and unique structure allow DHA to impart special membrane characteristics for effective cell signaling. Many development disorders like dyslexia, autism spectrum disorder, attention deficit hyperactivity disorder, schizophrenia etc. are causally related to decreased level of DHA . DHA is a potent RXR ligand inducing robust RXR activation already at low micro molar concentrations. The EC50 for RXRα activation by DHA is about 5-10 μM fatty acid . In Vivo: Docosahexaenoic acid administration over 10 weeks significantly reduces the number of reference memory errors, without affecting the number of working memory errors, and significantly increases the docosahexaenoic acid content and the docosahexaenoic acid/arachidonic acid ratio in both the hippocampus and the cerebral cortex . DHA treatment exerts neuroprotective actions on an experimental mouse model of PD. There is a decrease tendency in brain lipid oxidation of MPTP mice but it does not significantly .
    Docosahexaenoic acid (Standard)
  • HY-B2167S
    Docosahexaenoic acid-d5

    DHA-d5; Cervonic acid-d5

    		 Endogenous Metabolite Neurological Disease
    Docosahexaenoic acid-d5 is the deuterium labeled Docosahexaenoic Acid. Docosahexaenoic Acid (DHA) is an omega-3 fatty acid abundantly present brain and retina. It can be obtained directly from fish oil and maternal milk.
    Docosahexaenoic acid-d5
  • HY-B2167S2
    Docosahexaenoic acid-13C4

    		Isotope-Labeled Compounds Endogenous Metabolite Neurological Disease Cancer
    Docosahexaenoic acid- 13C4 is 13C labeled Docosahexaenoic acid. Docosahexaenoic Acid (DHA) is an omega-3 fatty acid abundantly present brain and retina. It can be obtained directly from fish oil and maternal milk .
    Docosahexaenoic acid-13C4
  • HY-130289
    (±)4-HDHA

    4-Hydroxy docosahexaenoic acid; (±)4-HDoHE

    		 PPAR Metabolic Disease Inflammation/Immunology
    (±)4-HDHA (4-Hydroxy docosahexaenoic acid) is an autoxidation product of Docosahexaenoic acid (HY-B2167) (DHA). (±)4-HDHA is a PPARγ agonist, antidiabetic and anti-inflammatory agent .
    (±)4-HDHA
  • HY-120442
    (±)16(17)-DiHDPA

    		COX Cardiovascular Disease
    (±)16(17)-DiHDPA is a epoxygenase metabolite of docosahexaenoic acid (HY-B2167). (±)16(17)-DiHDPA inhibits platelet aggregation at concentrations below those affecting thromboxane synthesis .
    (±)16(17)-DiHDPA
  • HY-172548
    Docosahexaenoyl-L-carnitine chloride

    		Carnitine Palmitoyltransferase (CPT) Endogenous Metabolite Metabolic Disease
    Docosahexaenoyl-L-carnitine chloride is a long-chain acylcarnitine composed of Docosahexaenoic acid (HY-B2167) and L-carnitine (HY-B0399). Docosahexaenoyl-L-carnitine chloride is transported into mitochondria for β -oxidation and decomposition under the action of carnitine palmitoyltransferase I (CPT I) and others. Docosahexaenoyl-L-carnitine chloride is promising for research of diseases related to fatty acid metabolism .
    Docosahexaenoyl-L-carnitine chloride
  • HY-120178
    (±)7(8)-DiHDPA

    		COX Cardiovascular Disease
    (±)7(8)-DiHDPA is a epoxygenase metabolite of docosahexaenoic acid (HY-B2167). (±)7(8)-DiHDPA inhibits platelet aggregation at concentrations below those affecting thromboxane synthesis .
    (±)7(8)-DiHDPA
  • HY-158594
    Docosahexaenoic acid alkyne

    DHA-alkyne; FA 22:8

    		 Drug Derivative Others
    Docosahexaenoic acid alkyne (FA 22:8) is the ω-alkyne derivative of Docosahexaenoic acid (HY-B2167) .
    Docosahexaenoic acid alkyne
  • HY-157690
    19(S),20(R)-EDP

    		Drug Metabolite Others
    19(S),20(R)-EDP is an epoxidized metabolite of docosahexaenoic acid (HY-B2167) .
    19(S),20(R)-EDP
  • HY-120312
    PCTR3

    		Drug Derivative Others
    PCTR3 is a Docosahexaenoic acid DHA (HY-B2167) derivative, which acts as a pro-resolving and tissue regeneration lipid mediator .
    PCTR3
  • HY-158623
    (±)13(14)-DiHDPA

    (±)13,14-DiHDPE

    		 Drug Metabolite Inflammation/Immunology
    (±)13(14)-DiHDPA ((±)13,14-DiHDPE) a metabolite of Docosahexaenoic acid (DHA; HY-B2167) by P450 (CYP) metabolic pathways .
    (±)13(14)-DiHDPA
  • HY-19886
    F 16915

    		Drug Intermediate Cardiovascular Disease
    F 16915, a Docosahexaenoic Acid (DHA, HY-B2167) derivative, is a potent pro-agent of DHA. F 16915 can prevent heart failure-induced atrial fibrillation .
    F 16915
  • HY-157690A
    19(R),20(S)-EDP

    		Drug Metabolite Others
    19(R),20(S)-EDP (compound 19(S),20(R)-2a) is an oxylipin and a metabolite of docosahexaenoic acid (HY-B2167) .
    19(R),20(S)-EDP
  • HY-142974
    1,2-Dioleoyl-3-Docosohexaenoyl-rac-glycerol

    1,2-Olein-3-Docosohexaenoin; 18:1/18:1/22:6-TG; C1OO

    		 Endogenous Metabolite Metabolic Disease
    1,2-Dioleoyl-3-docosohexaenoyl-rac-glycerol is a triacylglycerol that contains oleic acid (HY-N1446) at the sn-1 and sn-2 positions and docosahexaenoic acid (HY-B2167) at the sn-3 position. It has been detected in human breast milk.
    1,2-Dioleoyl-3-Docosohexaenoyl-rac-glycerol
  • HY-W708469
    Resolvin D2 methyl ester

    		Endogenous Metabolite TRP Channel Inflammation/Immunology
    Resolvin D2 methyl ester is an ester derivative of the DHA (HY-B2167) metabolite Resolvin D2 (HY-121636) with anti-inflammatory and anti-infective activities. Resolvin D2 is a leukocyte modulator and a potent inhibitor of neuronal TRPV1 (IC50=0.1 nM) and TRPA1 (IC50=2 nM). Resolvin D2 can be used in sepsis research .
    Resolvin D2 methyl ester
  • HY-134997
    4-Oxo Docosahexaenoic Acid

    4-oxo DHA

    		 PPAR Cancer
    4-oxo Docosahexaenoic acid (4-oxo DHA) is a putative metabolite of Docosahexaenoic acid (HY-B2167) with antiproliferative and PPARγ agonist activity. It inhibits the growth of several triple negative breast cancer cell lines (MCF-10F, trMCF, bsMCF, MDA-MB-231, and BT549) at 50-100 μM, however it increased proliferation of MCF-7 cells. 4-oxo DHA binds covalently to PPARγ and activates gene transcription in luciferase reporter assays and in dendritic cells with EC50 values of approximately 8-16 μM.
    4-Oxo Docosahexaenoic Acid
  • HY-116115
    17-Oxo-7(Z),10(Z),13(Z),15(E),19(Z)-docosapentaenoic acid

    17-Oxo-DPA; 17-Oxo-7(Z),10(Z),13(Z),15(E),19(Z)-DPA

    		 NF-κB PPAR Inflammation/Immunology
    17-Oxo-7(Z),10(Z),13(Z),15(E),19(Z)-docosapentaenoic acid (17-Oxo-DPA; 17-Oxo-7(Z),10(Z),13(Z),15(E),19(Z)-DPA) is an electrophilic oxo-derivative (EFOX) of the docosahexaenoic acid (DHA) (HY-B2167). 17-Oxo-7(Z),10(Z),13(Z),15(E),19(Z)-docosapentaenoic acid is generated during inflammation by COX-2-catalyzed mechanism in activated macrophages. 17-Oxo-7(Z),10(Z),13(Z),15(E),19(Z)-docosapentaenoic acid acts as an agonist for PPARγ and a modulator for NF-κB signaling pathway, inhibits the production of pro-inflammatory cytokines and nitric oxide, and exhibits anti-inflammatory efficacy .
    17-Oxo-7(Z),10(Z),13(Z),15(E),19(Z)-docosapentaenoic acid
  • HY-170676
    1,3-Dilinoleoyl-2-docosahexaenoyl glycerol

    		Biochemical Assay Reagents Metabolic Disease
    1,3-Dilinoleoyl-2-docosahexaenoyl glycerol is a triacylglycerol that contains Linoleic acid (HY-N0729) at the sn-1 and sn-3 positions and Docosahexaenoic acid (HY-B2167) at the sn-2 position.
    1,3-Dilinoleoyl-2-docosahexaenoyl glycerol
  • HY-168783
    7(Z),10(Z),13(Z)-Hexadecatrienoic acid methyl ester

    		Drug Derivative Others
    7(Z),10(Z),13(Z)-Hexadecatrienoic acid methyl ester is a polyunsaturated fatty acid generated during the synthesis of Docosahexaenoic acid-d5 (HY-B2167S) .
    7(Z),10(Z),13(Z)-Hexadecatrienoic acid methyl ester

Inquiry Online

Your information is safe with us. * Required Fields.

Salutation

  

Country or Region *

Applicant Name *

 

Organization Name *

Department *

     

Email Address *

 

Product Name *

Cat. No.

  

Requested quantity *

Phone Number *

     

Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: