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F 16915 

Cat. No.: HY-19886 Purity: 99.39%
COA Handling Instructions

F 16915, a Docosahexaenoic Acid (DHA, HY-B2167) derivative, is a potent pro-agent of DHA. F 16915 can prevent heart failure-induced atrial fibrillation.

For research use only. We do not sell to patients.

F 16915 Chemical Structure

F 16915 Chemical Structure

CAS No. : 92510-91-3

Size Price Stock Quantity
Solution
10 mM * 1 mL in DMSO USD 1849 In-stock
Oil + Solvent
10 mM * 1 mL
ready for reconstitution
 USD 1849 In-stock
Oil
1 mg USD 1252 In-stock
5 mg USD 2003 In-stock
10 mg USD 3273 In-stock
50 mg   Get quote  
100 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

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Description

F 16915, a Docosahexaenoic Acid (DHA, HY-B2167) derivative, is a potent pro-agent of DHA. F 16915 can prevent heart failure-induced atrial fibrillation[1].

In Vivo

F 16915 (100 mg/kg; daily oral gavage for 2 months) reduces marked dilation of the left atrial (LA) cavity and the steep decline of left ventricular (LV) contractile function occurring 2 months after infarction and reperfusion in rats[1].
F 16915 (1-5 g/day for 4 weeks) significantly reduces the infarct size and prevents the left ventricular free wall thinning[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male Sprague-Dawley rats (220-300 g) with heart failure induced by occlusion of left descending coronary artery and 2 months reperfusion[1]
Dosage: 100 mg/kg
Administration: Daily oral gavage
Result: Reduced the infarct size.
Prevented the left ventricular free wall thinning.
Reduced the de-phosphorylation of connexin43 from atria tissue.
Molecular Weight

419.60

Appearance

Oil

Formula

C28H37NO2
CAS No.
SMILES

CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCC(OCC1=CC=CN=C1)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
In Vitro: 

DMSO : ≥ 100 mg/mL (238.32 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.3832 mL 11.9161 mL 23.8322 mL
5 mM 0.4766 mL 2.3832 mL 4.7664 mL
10 mM 0.2383 mL 1.1916 mL 2.3832 mL
*Please refer to the solubility information to select the appropriate solvent.
Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Keywords:

F 1691592510-91-3F16915F-16915OthersDocosahexaenoicAcidDHAheartfailureatrialfibrillationInhibitorinhibitorinhibit

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