Docosahexaenoic acid alkyne
Docosahexaenoic acid alkyne (DHA-alkyne) is an ω-alkyne derivative of Docosahexaenoic acid (HY-B2167). Docosahexaenoic acid alkyne can be used in cancer-related research.
For research use only. We do not sell to patients.
- CAS No.: 2692622-57-2
- Formula: C22H28O2
- Molecular Weight:324.46
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
In Vitro
DHA alkyne (10 μM; 6 h) localizes predominantly to the endoplasmic reticulum, Golgi, late endosomes, and mitochondria in HT29 cells[1].
Docosahexaenoic acid alkyne (10 μM; 6 h) localizes to mitochondria, endoplasmic reticulum, and late endosomes, but not to the Golgi, early endosomes or plasma membrane, in PDTO CRC0124[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
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Cell Line:HT29 colorectal cancer cells
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Concentration:10 μM
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Incubation Time:6 h
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Result:Was actively taken up by cells and was detectable mainly within intracellular compartments.
Accumulated prominently in the ER, Golgi and late endosomal compartments but not in the early endosomal compartments and stressed ER.
Localized considerably on mitochondria.
Chemical Information
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CAS No. 2692622-57-2
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Molecular Weight 324.46
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Formula C22H28O2
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SMILES
C#C/C=C\C/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCC(O)=O
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Synonyms
DHA-alkyne; FA 22:8
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)