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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
18 Results for "
BoNT
" in MedChemExpress (MCE) Product Catalog:
Products (18)
18 Results for "BoNT" in MCE Product Catalog:
2
2 Cited Publications
Cat. No.: HY-P0033
CAS No.: 616204-22-9
Synonyms: Acetyl hexapeptide-3; Acetyl hexapeptide-8
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Amifampridine (3,4-Diaminopyridine) is an orally active, potent and cell permeable voltage-gated potassium (Kv) channel blocker (PCB). Amifampridine is efficacy in the reversal of BoNT/A (HY-P79153) intoxication. Amifampridine increases transmitter release from neuromuscular junctions (NMJs). Amifampridine can be used for Lambert-Eaton myasthenic syndrome (LEMS) research .
Cat. No.: HY-18671
CAS No.: 694443-03-3
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BoNT-IN-1 is an effective inhibitor of botulinum toxin type A light chain (BoNTA LC), with an IC50 value of 0.9 μM.
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ADAMTS-5-IN-2 is an inhibitor of ADAMTS-5 (IC50: 9.6 μM) and BoNT/A LC (IC50: 0.71 μM). ADAMTS-5-IN-2 can be used in research related to botulism, osteoarthritis, and other conditions .
Cat. No.: HY-W596782
CAS No.: 75514-37-3
Synonyms: Chaetochromin
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Cat. No.: HY-P0033A
CAS No.: 2484708-86-1
Synonyms: Acetyl hexapeptide-3 acetate; Acetyl hexapeptide-8 acetate
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Cat. No.: HY-14946A
CAS No.: 446254-47-3
Synonyms: 3,4-Diaminopyridine phosphate
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Amifampridine (3,4-Diaminopyridine) phosphate is an orally active, potent and cell permeable voltage-gated potassium (Kv) channel blocker (PCB). Amifampridine phosphate is efficacy in the reversal of BoNT/A (HY-P79153) intoxication. Amifampridine phosphate increases transmitter release from neuromuscular junctions (NMJs). Amifampridine phosphate can be used for Lambert-Eaton myasthenic syndrome (LEMS) research .
Cat. No.: HY-176052
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PPO-allene is a covalent botulinum neurotoxin (BoNT) light chain inhibitor (IC50: 20.9 μM). PPO-allene (0.3 mg/kg, i.v.) demonstrates an in vivo half-life of approximately 1.5 h in mice .
Cat. No.: HY-P1820
CAS No.: 216568-37-5
Cat. No.: HY-118851
CAS No.: 77308-57-7
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NSC-77053 is a potent BoNT/E inhibitor with an IC50 and a Ki of 2.4 μM and 1.29 μM, respectively .
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Amifampridine (Standard) is the analytical standard of Amifampridine. This product is intended for research and analytical applications. Amifampridine (3,4-Diaminopyridine) is an orally active, potent and cell permeable voltage-gated potassium (Kv) channel blocker (PCB). Amifampridine is efficacy in the reversal of BoNT/A (HY-P79153) intoxication. Amifampridine increases transmitter release from neuromuscular junctions (NMJs). Amifampridine can be used for Lambert-Eaton myasthenic syndrome (LEMS) research .
Cat. No.: HY-14946S
CAS No.: 2732980-95-7
Synonyms: 3,4-Diaminopyridine-d3
Cat. No.: HY-W002097R
CAS No.: 13679-74-8
Synonyms: 2-Acetyl-5-methylthiophene (Standard)
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Cat. No.: HY-P79182
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Botulinum neurotoxin type B; BoNT/B; BoNToxilysin-B; Botulinum Neurotoxin Type B Light Chain
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Cat. No.: HY-P79153
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Botulinum neurotoxin type A2; BoNT/A; BoNToxilysin-A; BOTOX; Botulinum Neurotoxin Type A Light Chain
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
