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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
11 Results for "
CNE-2
" in MedChemExpress (MCE) Product Catalog:
Products (11)
11 Results for "CNE-2" in MCE Product Catalog:
69
Target:
Research Areas:
Oxamic acid (oxamate) sodium salt is a lactate dehydrogenase-A (LDH-A) inhibitor. Oxamic acid sodium salt shows anti-tumor activity, and anti-proliferative activity against cancer cells, and can induce apoptosis [2] .
69
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Target:
5
5 Cited Publications
Cat. No.: HY-N2959
CAS No.: 16503-32-5
2
2 Cited Publications
Cat. No.: HY-N6843
CAS No.: 34532-68-8
2
2 Cited Publications
Cat. No.: HY-N6954
CAS No.: 76996-27-5
Cat. No.: HY-RS16343
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Research Areas:
CNE-2 Human Pre-designed siRNA Set A contains three designed siRNAs for CNE-2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-111137
CAS No.: 916890-10-3
Synonyms: XC-302 free base
Puquitinib (XC-302 free base) is a multi-target inhibitor with the activity of inducing autophagy in nasopharyngeal carcinoma cells by inhibiting the PI3K/AKT/mTOR signaling pathway. Puquitinib was able to inhibit the proliferation of CNE-2 cells, showing a dose-dependent antiproliferative effect. Puquitinib induced the formation of autophagosomes and autolysosomes in CNE-2 cells, which were observed by fluorescence microscopy and electron microscopy. Puquitinib promoted the formation of LC3-II and increased the expression of beclin 1, while reducing the level of p62. Puquitinib inhibited the PI3K/AKT/mTOR pathway by reducing the expression of p-AKT and p-mTOR. Puquitinib also induced apoptosis in CNE-2 cells, and when autophagy was inhibited, the apoptosis rate was reduced, which means that autophagy may interact with apoptosis to induce cell death .
Cat. No.: HY-N6954R
CAS No.: 76996-27-5
Category:
other families Xanthones Garcinia oblongifolia Champ. ex Benth. Guttiferae Phenols Polyphenols Plants
Target:
Cat. No.: HY-W013032R
CAS No.: 471-47-6
Synonyms: Oxamidic acid (Standard)
Category:
Cat. No.: HY-N2959R
CAS No.: 16503-32-5
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Category:
Target:
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
