565-73-1
565-73-1
Chemical Structure
Oxamic acid sodium
Synonym(s): Sodium oxamate
- CAS No.: 565-73-1
- Formula:C2H2NNaO3
- Molecular Weight:111.03
IUPAC Name: sodium 2-amino-2-oxoacetate
InChIKey: RQVZIJIQDCGIKI-UHFFFAOYSA-M
SMILES: [Na].O=C(O)C(=O)N
Biological Activity: Oxamic acid (oxamate) sodium salt is a lactate dehydrogenase-A (LDH-A) inhibitor. Oxamic acid sodium salt shows anti-tumor activity, and anti-proliferative activity against cancer cells, and can induce apoptosis[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Oxamic acid sodium | 99.72% | Oxamic acid (oxamate) sodium salt is a lactate dehydrogenase-A (LDH-A) inhibitor. Oxamic acid sodium salt shows anti-tumor activity, and anti-proliferative activity against cancer cells, and can induce apoptosis. | ||||||||||||||||||||
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References
- [1]. Xiang J, et al. LDH-A inhibitors as remedies to enhance the anticancer effects of PARP inhibitors in ovarian cancer cells. Aging (Albany NY). 2021 Dec 16;13(24):25920-25930. [Content Brief]
- [2]. Zhai X, et al. Inhibition of LDH-A by oxamate induces G2/M arrest, apoptosis and increases radiosensitivity in nasopharyngeal carcinoma cells. Oncol Rep. 2013 Dec;30(6):2983-91. [Content Brief]
- [3]. Muramatsu H, et al. Targeting lactate dehydrogenase‑A promotes docetaxel‑induced cytotoxicity predominantly in castration‑resistant prostate cancer cells. Oncol Rep. 2019 Jul;42(1):224-230. [Content Brief]
