565-73-1
565-73-1
Chemical Structure
Oxamic acid sodium
Synonym(s): Sodium oxamate
- CAS No.: 565-73-1
- Formula:C2H2NNaO3
- Molecular Weight:111.03
IUPAC Name: sodium 2-amino-2-oxoacetate
InChIKey: RQVZIJIQDCGIKI-UHFFFAOYSA-M
SMILES: [Na].O=C(O)C(=O)N
Biological Activity: Oxamic acid (oxamate) sodium salt is a lactate dehydrogenase-A (LDH-A) inhibitor. Oxamic acid sodium salt shows anti-tumor activity, and anti-proliferative activity against cancer cells, and can induce apoptosis[1][2][3].
| Cat. No. | Nom du produit | Pureté | Description | Pricing | |||||||||||||||||||
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Oxamic acid sodium | 99.72% | Oxamic acid (oxamate) sodium salt is a lactate dehydrogenase-A (LDH-A) inhibitor. Oxamic acid sodium salt shows anti-tumor activity, and anti-proliferative activity against cancer cells, and can induce apoptosis. | ||||||||||||||||||||
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Sodium 2-oxobutanoate | 99.95% | Sodium 2-oxobutanoate is an organic compound commonly used as a food additive and industrial raw material. It can be used as an acidity regulator, leavening agent and preservative, and is often used in the fields of bread, baked goods and canning. In addition, the compound is used in the production of certain industrial products, such as in plastics, textiles and dyes. | ||||||||||||||||||||
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Oxamic acid | 98.0% | Oxamic acid is a lactate dehydrogenase-A (LDH-A) inhibitor. Oxamic acid shows anti-tumor activity, and anti-proliferative activity against cancer cells, and can induce apoptosis. | ||||||||||||||||||||
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Oxalic acid ammonium | 98.40% | Oxalic acid (Ethanedioic acid) ammonium is a dicarboxylic acid. Oxalic acid ammonium is widely found in various plants. Oxalic acid ammonium has antioxidant activity and can inhibit lipid peroxidation. Oxalic acid ammonium is a pathogenic factor of Sclerotinia sclerotiorum and can inhibit the oxidative burst of host plants. Oxalic acid ammonium has acaricidal activity. Oxalic acid ammonium can be used for related research on Sclerotinia sclerotiorum disease, Varroa mite disease and inflammatory diseases. | ||||||||||||||||||||
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Potassium hydrogen oxalate | 99.18% | Potassium hydrogen oxalate is a kind of biological materials or organic compounds that are widely used in life science research. | ||||||||||||||||||||
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Pyruvic acid-13C2 | 95% | Pyruvic acid-13C2 (Acetylformic acid-13C2) is the 13C-labeled Pyruvic acid (HY-Y0781). Pyruvic acid is an intermediate metabolite in the metabolism of carbohydrates, proteins, and fats. | ||||||||||||||||||||
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Oxalic acid, 99% (Standard) | 98.8% | Oxalic acid, 99% (Standard) is the analytical standard of Oxalic acid, 99%. This product is intended for research and analytical applications. Oxalic Acid is a strong dicarboxylic acid occurring in many plants and vegetables and can be used as an analytical reagent and general reducing agent. | ||||||||||||||||||||
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Oxalic acid-13C2 | 99.87% | Oxalic acid-13C2 is the deuterium labeled Oxalic acid, 99% (HY-Y0262). Oxalic Acid is a strong dicarboxylic acid occurring in many plants and vegetables and can be used as an analytical reagent and general reducing agent. | ||||||||||||||||||||
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Pyruvic acid (Standard) | 99.35% | Pyruvic acid (Standard) (Acetylformic acid (Standard)) is the analytical standard of Pyruvic acid (HY-Y0781). This product is intended for research and analytical applications. Pyruvic acid is an intermediate metabolite in the metabolism of carbohydrates, proteins, and fats. | ||||||||||||||||||||
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Pyruvic acid-13C | 96.59% | Pyruvic acid-13C (Acetylformic acid-13C) is the 13C-labeled Pyruvic acid (HY-Y0781). Pyruvic acid is an intermediate metabolite in the metabolism of carbohydrates, proteins, and fats. | ||||||||||||||||||||
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Pyruvic acid-13C-4 | Pyruvic acid-13C-4 (Acetylformic acid-13C-4) is the 13C-labeled Pyruvic acid (HY-Y0781). Pyruvic acid is an intermediate metabolite in the metabolism of carbohydrates, proteins, and fats. | |||||||||||||||||||||
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References
- [1]. Xiang J, et al. LDH-A inhibitors as remedies to enhance the anticancer effects of PARP inhibitors in ovarian cancer cells. Aging (Albany NY). 2021 Dec 16;13(24):25920-25930. [Content Brief]
- [2]. Zhai X, et al. Inhibition of LDH-A by oxamate induces G2/M arrest, apoptosis and increases radiosensitivity in nasopharyngeal carcinoma cells. Oncol Rep. 2013 Dec;30(6):2983-91. [Content Brief]
- [3]. Muramatsu H, et al. Targeting lactate dehydrogenase‑A promotes docetaxel‑induced cytotoxicity predominantly in castration‑resistant prostate cancer cells. Oncol Rep. 2019 Jul;42(1):224-230. [Content Brief]
