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112

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1

Fluorescent Dye

4

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7

Peptides

25

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3

Isotope-Labeled Compounds

8

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W010347
    L-Homocysteine
    5+ Cited Publications

    		 Endogenous Metabolite Cathepsin Cardiovascular Disease Inflammation/Immunology
    L-Homocysteine, an amino acid, is a homocysteine that has L configuration. Homocysteine is an essential intermediate in normal mammalian metabolism of methionine. L-Homocysteine induces upregulation of Cathepsin V that mediates vascular endothelial inflammation in hyperhomocysteinaemia .
    L-Homocysteine
  • HY-W018035
    DL-Glyceric Acid (20% in water)
    1 Publications Verification

    Glyceric Acid (20% in Water,ca.2 mol/L)

    		 Endogenous Metabolite Metabolic Disease
    DL-Glyceric Acid (20% in water) is a metabolite of plants and mammals and exists in two configurations, D and L .
    DL-Glyceric Acid (20% in water)
  • HY-P1939
    Cyclo(L-Leu-L-Pro)

    Cyclo(L-prolyl-L-leucyl)

    		 Fungal Bacterial Influenza Virus Infection
    Cyclo(L-Leu-L-Pro) is a cyclic dipeptide with broad-spectrum antibacterial, antiviral and antifungal activities. Its biological activity is highly dependent on the stereoconfiguration and is widely present in microbial metabolites. Cyclo(L-Leu-L-Pro) efficiently and specifically inhibits the production of aflatoxin by Aspergillus flavus. The cis configuration of Cyclo(L-Leu-L-Pro) (cis-cyclo(L-Leu-L-Pro)) has broad-spectrum antibacterial activity against multi-drug resistant bacteria and significantly inhibits the influenza A virus H3N2 .
    Cyclo(L-Leu-L-Pro)
  • HY-30220
    (S)-2-Hydroxy-3-phenylpropanoic acid

    L-(-)-3-Phenyllactic Acid

    		 Endogenous Metabolite Fungal Infection Metabolic Disease
    (S)-2-Hydroxy-3-phenylpropanoic acid is the L-configuration of 2-Hydroxy-3-phenylpropanoic acid, and its level is closely related to some diseases, such as phenylketonuria .
    (S)-2-Hydroxy-3-phenylpropanoic acid
  • HY-113068
    (rel)-β-Tocopherol

    		Tyrosinase Metabolic Disease
    (rel)-β-Tocopherol is a relative configuration of β-Tocopherol. β-Tocopherol is a lipid-soluble form of vitamin E with antioxidant activity .
    (rel)-β-Tocopherol
  • HY-117693
    (E/Z)-Mirin
    Maximum Cited Publications
    9 Publications Verification

    		 ATM/ATR Cancer
    (E/Z)-Mirin is a mixture of (E)-Mirin and Mirin ((Z)-Mirin) (HY-19959) configurations. Among them, Mirin is an inhibitor of MRN (Mre11-Rad50-Nbs1). Mirin prevents MRN-dependent ATM activation without affecting ATM protein kinase activity .
    (E/Z)-Mirin
  • HY-164254
    Cardiomyocyte proliferation promoting agent-1

    (E/Z)-GA-002

    		 Large Tumor Suppressor (LATS) YAP Cardiovascular Disease Inflammation/Immunology Cancer
    Cardiomyocyte proliferation promoting agent-1 ((E/Z)-GA-002), which is an E/Z mixture, is a cardiomyocyte proliferation promoter. GA-002 (single E configuration) is a kinase inhibitor for LATS1 and LATS2, with its IC50 values being 3.93 nM and 3.87 nM respectively. GA-002 can induce the expression of genes regulated by the Hippo pathway, inhibit the phosphorylation of YAP/TAZ, and induce the nuclear translocation of YAP .
    Cardiomyocyte proliferation promoting agent-1
  • HY-W653733
    L-Homocysteine-d4
    1 Publications Verification

    		 Isotope-Labeled Compounds Endogenous Metabolite Cathepsin Cardiovascular Disease Inflammation/Immunology
    L-Homocysteine-d4 is deuterium labeled L-Homocysteine (HY-W010347) . L-Homocysteine, an amino acid, is a homocysteine that has L configuration. Homocysteine is an essential intermediate in normal mammalian metabolism of methionine. L-Homocysteine induces upregulation of Cathepsin V that mediates vascular endothelial inflammation in hyperhomocysteinaemia
    L-Homocysteine-d4
  • HY-13859
    Clevudine
    1 Publications Verification

    L-FMAU

    		 HBV DNA/RNA Synthesis Orthopoxvirus Infection
    Clevudine (L-FMAU), a nucleoside analog of the unnatural L-configuration, has potent anti-HBV activity with long half-life, low toxicity. Clevudine is a non-competitive inhibitor that is not incorporated into the viral DNA but rather binds to the polymerase. Clevudine is active against cowpox virus respiratory infection in mice .
    Clevudine
  • HY-W008922
    Fmoc-D-3,3-diphenylalanine

    		Amino Acid Derivatives Others
    Fmoc-D-3,3-diphenylalanine is a non-natural D-configuration amino acid derivative protected by Fmoc and commonly used in peptide synthesis research.
    Fmoc-D-3,3-diphenylalanine
  • HY-148165
    L-Cytidine

    		Nucleoside Antimetabolite/Analog Neurological Disease
    L-Cytidine is an L-configurational form of Cytidine (HY-B0158). L-Cytidine is a pyrimidine nucleoside, a component of RNA. Cytidine can control the glial glutamate cycle, affect brain phospholipid metabolism, catecholamine synthesis and mitochondrial function .
    L-Cytidine
  • HY-145728B
    (R/S)-Alicaforsen

    (R/S)-ISIS-2302

    		 Integrin Inflammation/Immunology
    (R/S)-Alicaforsen is the racemate of Alicaforsen composed of R and S configurations. Alicaforsen is a 20-base antisense oligonucleotide inhibiting ICAM-1 production, which is an important adhesion molecule involved in leukocyte migration and trafficking to the site of inflammation.
    (R/S)-Alicaforsen
  • HY-160440
    rel-VU6021625

    		mAChR Drug Isomer Others
    rel-VU6021625 is the relative configuration of VU6021625 (HY-160440A). VU6021625 is a potent and selective mAChR M4 antagonist with IC50 values of 0.44 nM and 57 nM for human M4, rat M4, respectively .
    rel-VU6021625
  • HY-148864
    JQ1-TCO

    		Epigenetic Reader Domain Cancer
    JQ1-TCO is the double bond E configuration of JQ1-TCO (HY-148864A). JQ1-TCO is a derivative of JQ1 (HY-13030), an inhibitor of BET. JQ1-TCO is suitable for click chemistry and can be used as molecular probes in vitro and in vivo .
    JQ1-TCO
  • HY-W074648
    Antibacterial agent 18

    		MOFs Bacterial Infection
    Antibacterial agent 18 is a multi-arm AIE molecule extracted from patent CN110123801A, compound 23. Antibacterial agent 18 can be used for resisting Gram-positive and Gram-negative bacteria. Antibacterial agent 18 can be conjugated in the cell wall of rigid arm configuration insertion bacterium, and block cell wall turns sugar and turns peptide process, to inhibit or kill bacterium .
    Antibacterial agent 18
  • HY-138130
    L-Guanosine

    		Nucleoside Antimetabolite/Analog Infection
    L-Guanosine is the L-configuration of Guanosine (HY-N0097). L-Guanosine is a purine nucleoside with anti-herpesvirus activity. L-Guanosine can be used to prepare supramolecular hydrogel .
    L-Guanosine
  • HY-148169
    2'-Deoxy-L-guanosine

    		Nucleoside Antimetabolite/Analog Infection
    2'-Deoxy-L-guanosine selectively inhibits D-Thymidine phosphorylation catalyzed by HSV 1 thymidine kinase. 2'-Deoxy-L-guanosine is the L-configuration of 2'-Deoxyguanosine (HY-17563) .
    2'-Deoxy-L-guanosine
  • HY-W001959
    D-Allothreonine

    		Endogenous Metabolite Metabolic Disease
    D-Allothreonine is the D stereoisomer of Allothreonine. D-Allallreonine is a peptide lipid derived from bacteria. D-Allothreonine can be specifically oxidized by D-amino acid oxidase, while the L configuration has no reaction. D-Allallreonine is also a component of bacterial polysaccharides. D-Allallreonine can be used for researching bacterial pathogenicity, antigenic diversity and drug resistance .
    D-Allothreonine
  • HY-W337569
    (±)-Voriconazole

    (±)-UK-109496

    		 Fungal Others
    (±)-Voriconazole ((±)-UK-109496) is a relative configuration of Voriconazole (HY-76200). Voriconazole is an antifungal agent .
    (±)-Voriconazole
  • HY-152953
    (R)-Lactoyl-CoA

    (R)-Lactoyl-coenzyme A

    		 Biochemical Assay Reagents Metabolic Disease
    (R)-Lactoyl-CoA ((R)-Lactoyl-coenzyme A) is a lactoyl-CoA in which the lactoyl residue has (R)-configuration.
    (R)-Lactoyl-CoA
  • HY-ER013I
    Sodium carbonate anhydrous, meets analytical specification of Ph. Eur., BP, NF, FCC, E500

    Calcined soda meets analytical specification of Ph. Eur., BP, NF, FCC, E500

    		 Biochemical Assay Reagents Neurological Disease
    Sodium carbonate anhydrous, meets analytical specification of Ph. Eur., BP, NF, FCC, E500 is a biochemical assay reagent suitable for buffer configuration .
    Sodium carbonate anhydrous, meets analytical specification of Ph. Eur., BP, NF, FCC, E500
  • HY-147251
    SRI 6409-94

    		Drug Derivative Others
    SRI 6409-94 is an orally active Ro 13-6298 analogue that is teratogenic. SRI 6409-94 serves as a molecular tool to study the effect of the three-dimensional configuration of retinol on teratogenic activity .
    SRI 6409-94
  • HY-W010347R
    L-Homocysteine (Standard)

    		Reference Standards Endogenous Metabolite Cathepsin Cardiovascular Disease Inflammation/Immunology
    L-Homocysteine (Standard) is the analytical standard of L-Homocysteine. This product is intended for research and analytical applications. L-Homocysteine, an amino acid, is a homocysteine that has L configuration. Homocysteine is an essential intermediate in normal mammalian metabolism of methionine. L-Homocysteine induces upregulation of Cathepsin V that mediates vascular endothelial inflammation in hyperhomocysteinaemia[1][2].
    L-Homocysteine (Standard)
  • HY-W012885
    (S)-Methyl 3-hydroxybutanoate

    		Biochemical Assay Reagents Others
    (S)-Methyl 3-hydroxybutanoate consists of a chiral center, resulting in two enantiomers, where (S)-Methyl 3-hydroxybutanoate means that the hydroxyl group is located on the third carbon atom of the S-configuration carboxylic acid group stereoisomers. This compound is often used as a building block for the synthesis of various pharmaceuticals and natural products. Due to its fruity taste, it is also used as a flavor and fragrance ingredient.
    (S)-Methyl 3-hydroxybutanoate
  • HY-114324A
    rel-PROTAC PARP1 degrader

    		PROTACs PARP Cancer
    rel-PROTAC PARP1 degrader is the relative configuration of ROTAC PARP1 degrader (HY-114324). ROTAC PARP1 degrader is a PARP1 degrader based on MDM2 E3 ligand. It induces significant PARP1 cleavage and programmed cell death. PROTAC PARP1 degrader at 10 μM at 24 h inhibits MDA-MB-231 cell line with an IC50 of 6.12 μM.
    rel-PROTAC PARP1 degrader
  • HY-148166
    L-Inosine

    		Nucleoside Antimetabolite/Analog Others
    L-Inosine is the L-configuration of Inosine (HY-N0092). Inosine is an endogenous purine nucleoside produced by catabolism of adenosine. Inosine has anti-inflammatory, antinociceptive, immunomodulatory and neuroprotective effects .
    L-Inosine
  • HY-W740611
    Trihydroxycoprostane

    		Drug Intermediate Inflammation/Immunology
    Trihydroxycoprostane (THCP) is a polyhydroxysterane compound with a 5β configuration. ITrihydroxycoprostane acts as a key intermediate in the biosynthesis of bile acids from cholesterol and also serves as an important sterol metabolite generated by host-gut microbiota interactions. Trihydroxycoprostane can be used for mechanistic studies of diseases such as non-alcoholic fatty liver disease, inflammatory bowel disease, and bile acid metabolism disorders .
    Trihydroxycoprostane
  • HY-14282A
    (Z)-Lanoconazole

    		Fungal Infection Inflammation/Immunology
    (Z)-Lanoconazole is the Z configuration of Lanoconazole. Lanoconazole is a potent and orally active imidazole antifungal agent, shows a broad spectrum of activity against fungi in vitro and in vivo . Lanoconazole interferes with ergosterol biosynthesis by inhibiting sterol 14-alpha demethylase and blocking fungal membrane ergosterol biosynthesis. Lanoconazole can be used for the investigation of dermatophytosis and onychomycosis .
    (Z)-Lanoconazole
  • HY-119426
    Dexamisole

    (+)-Tetramisole; Dextramisole

    		 Adrenergic Receptor Neurological Disease
    Dexamisole has R configuration that has a role as an antidepressant .
    Dexamisole
  • HY-W160625
    3,5-Dimethyl-2-cyclohexen-1-one

    		Others Others
    3,5-Dimethyl-2-cyclohexen-1-one is a precursor to configurationally locked polyene chromophores with a mono-methylated cyclohexene ring .
    3,5-Dimethyl-2-cyclohexen-1-one
  • HY-B0196B
    (S)-Venlafaxine

    		Serotonin Transporter Cancer
    (S)-Venlafaxine is the (S)-configuration of Venlafaxine. Venlafaxine is an orally active, potent serotonin (5-HT)/norepinephrine (NE) reuptake dual inhibitor. Venlafaxine is an antidepressant agent .
    (S)-Venlafaxine
  • HY-177712
    RORγt inverse agonist 36

    		ROR Inflammation/Immunology
    RORγt inverse agonist 36 (S configuration of Compound 16) is a RORγt inverse agonist. RORγt inverse agonist 36 can be used for the research of inflammation and immunology .
    RORγt inverse agonist 36
  • HY-10082A
    (E)-3-AP

    (E)-PAN-811; (E)-NSC# 663249; (E)-OCX191

    		 DNA/RNA Synthesis Cancer
    (E)-3-AP is the E configuration of 3-AP. 3-AP is a potent ribonucleotide reductase inhibitor. 3-AP shows anti-proliferative activity. 3-AP shows anticancer activity in L1210 leukemia model. 3-AP inhibits RR activity and DNA synthesis .
    (E)-3-AP
  • HY-W856375
    (E)-BSPOTPE

    		MOFs Fluorescent Dye Others
    (E)-BSPOTPE is the E configuration of BSPOTPE (HY-W856375A). BSPOTPE binds Human serum albumin (HSA) (HY-P1956), exhibits aggregation-induced emission (AIE) phenomenon. BSPOTPE shows selectivity for albumin (such as HSA and BSA), but has no obvious fluorescence response to other proteins and DNA. BSPOTPE can be used as fluorescent probe for HSA .
    (E)-BSPOTPE
  • HY-122359A
    rel-Levormeloxifene

    rel-L-Centchroman; Ormeloxifene

    		 Estrogen Receptor/ERR Apoptosis Reactive Oxygen Species (ROS) Cancer
    rel-Levormeloxifene (rel-L-Centchroman) is the relative configuration of Levormeloxifene (HY-122359). rel-Levormeloxifene is a selective estrogen receptor modulator (SERM). rel-Levormeloxifene inhibits proliferation of leukemia cells with IC50 about 7 μM, arrests cell cycle at G0/G1 phase, and induces apoptosis. rel-Levormeloxifene induces differentation of myelogenesis leukemia, and enhances ROS production in K562 cells .
    rel-Levormeloxifene
  • HY-101960
    (Z)-Tyrphostin A51

    (Z)-AG-183

    		 EGFR Others
    (Z)-Tyrphostin A51 is the Z configuration of Lanoconazole A51. Tyrphostin A51 is a potent protein tyrosine kinase (PTK) inhibitor. Tyrphostin A51 inhibits the volume-dependent release of [ 3H]taurine in a dose-dependent manner. Tyrphostin A51 markedly reduces cellular tyrosyl phosphorylation level. Tyrphostin A51 inhibits both basal and EGF-induced human bone cell proliferation .
    (Z)-Tyrphostin A51
  • HY-169946A
    WEE1/PKMYT1-IN-2

    		Wee1 Cancer
    WEE1/PKMYT1-IN-2 is the axial chiral P configuration of WEE1/PKMYT1-IN-1 (HY-169946). WEE1/PKMYT1-IN-1 is a potent and orally active WEE1 and PKMYT1 inhibitor. WEE1/PKMYT1-IN-1 shows antiproliferation activity .
    WEE1/PKMYT1-IN-2
  • HY-121125
    Aucubigenin

    		Others Others
    Aucubigenin, the aglycone of the iridoid glycoside aucubin, has been characterized through X-ray diffraction analysis. Its crystal structure reveals monoclinic symmetry with specific conformations adopted by its cyclopentane and pyran rings. The study also determined the absolute configurations of both aucubin and aucubigenin. Significant O-H O hydrogen bonding interactions were observed in the crystal lattices of both compounds, highlighting their structural stability and potential for intermolecular interactions .
    Aucubigenin
  • HY-169946B
    WEE1/PKMYT1-IN-3

    		Wee1 Cancer
    WEE1/PKMYT1-IN-3 is the axial chiral M configuration of WEE1/PKMYT1-IN-1 (HY-169946). WEE1/PKMYT1-IN-1 is a potent and orally active WEE1 and PKMYT1 inhibitor. WEE1/PKMYT1-IN-1 shows antiproliferation activity .
    WEE1/PKMYT1-IN-3
  • HY-113068R
    (rel)-β-Tocopherol (Standard)

    		Reference Standards Tyrosinase Metabolic Disease
    (rel)-β-Tocopherol (Standard) is the analytical standard of (rel)-β-Tocopherol. This product is intended for research and analytical applications. (rel)-β-Tocopherol is a relative configuration of β-Tocopherol.(±)-β-Tocopherol is a lipid-soluble form of vitamin E with antioxidant activity. β-Tocopherol can inhibit tyrosinase activity and melanin synthesis. β-Tocopherol also can prevent the inhibition of cell growth and of PKC activity caused by d-alpha-tocopherol .
    (rel)-β-Tocopherol (Standard)
  • HY-N9761
    Murrayanine

    		Others Others
    Murrayanine is a dimeric pyranoquinoline alkaloid, a mixture of two enantiomers with a predominant configuration on the chiral axis .
    Murrayanine
  • HY-125949
    Kanshone H

    		Others Others
    Kanshone H (compound 6) is a sesquiterpene compound isolated from the underground parts of spikenard .
    Kanshone H
  • HY-106841A
    (S)-Draflazine

    (-)-Draflazine; (S)-R-75231; (S)-R88021

    		 Adenosine Receptor Drug Isomer Others
    (S)-Draflazine ((-)-Draflazine) is the (S)-configuration of Draflazine (HY-106841). (S)-Draflazine is a potent blocker of nucleoside transport .
    (S)-Draflazine
  • HY-109092A
    rel-Licogliflozin

    rel-LIK066

    		 SGLT Metabolic Disease Inflammation/Immunology
    rel-Licogliflozin is a relative configuration of Licogliflozin (HY-109092). Licogliflozin is a sodium glucose cotransporter (SGLT1 and SGLT2) inhibitor .
    rel-Licogliflozin
  • HY-P3045
    Bilaid B

    		Opioid Receptor Others
    Bilaid B (compound 2a) is a tetrapeptide. Bilaid B resembles opioid peptides albeit with a unique, alternating LDLD amino acid configuration. .
    Bilaid B
  • HY-W098280
    Phenylglycine methyl ester

    		Biochemical Assay Reagents Others
    Phenylglycine methyl ester is a chiral anisotropic reagent. Phenylglycine methyl ester can be used for absolute configuration determination of various chiral carboxylic acids .
    Phenylglycine methyl ester
  • HY-125644
    L-Lombricine

    		Amino Acid Derivatives Others
    L-Lombricine is a D-configuration amino acid, which can be isolated from Lumbricus terrestris. L-Lombricine is related to the energy storage in earthworms .
    L-Lombricine
  • HY-135386
    5β-​Dutasteride

    		Drug Metabolite Inflammation/Immunology
    5β-Dutasteride is the S configuration of Dutasteride. 5β-Dutasteride is a potent inhibitor of both 5 alpha-reductase isozymes .
    5β-​Dutasteride
  • HY-18957A
    rel-Lifirafenib

    rel-BGB-283

    		 Raf EGFR Cancer
    rel-Lifirafenib (rel-BGB-283) is the relative configuration of Lifirafenib (HY-18957). Lifirafenib is a potent Raf Kinase and EGFR inhibitor .
    rel-Lifirafenib
  • HY-N15739
    (rel)-ent-Chromazonarol

    		Biochemical Assay Reagents Others
    (rel)-ent-Chromazonarol is the relative configuration of ent-Chromazonarol and is a sesquiterpene hydroquinone compound. (rel)-ent-Chromazonarol can be isolated from the sponge Disidea pallescens .
    (rel)-ent-Chromazonarol

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