1 Result for "

DPP-4-IN-17

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "DPP-4-IN-17" in MCE Product Catalog:

Cat. No.: HY-175590
Target:  

Dipeptidyl Peptidase

Research Areas:  

Metabolic Disease

DPP-4-IN-17 is an orally active and selective dipeptidyl peptidase-4 (DPP-4) inhibitor with an IC50 value of 0.12 nM. DPP-4-IN-17 increases the enzyme's Km value (75.73 μM vs. 27.18 μM of substrate alone) and reduces catalytic efficiency. DPP-4-IN-17 reduces blood glucose levels and reverses weight loss in Streptozotocin (STZ) (HY-13753)/Nicotinamide (NA) (HY-B0150)-induced diabetic rats. DPP-4-IN-17 can be used for the study of type 2 diabetes mellitus (T2DM) .
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