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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
14 Results for "
Deoxyhypusine
" in MedChemExpress (MCE) Product Catalog:
Products (14)
14 Results for "Deoxyhypusine" in MCE Product Catalog:
Cat. No.: HY-121722
CAS No.: 82543-85-9
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Deoxyhypusine is an unusual amino acid formed during the posttranslational modification of eukaryotic translation initiation factor 5A (eIF-5A) by the enzyme deoxyhypusine hydroxylase (DOHH) .
16
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Cardiovascular Disease Inflammation/Immunology Endocrinology Cancer
8
8 Cited Publications
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GC7 Sulfate is a deoxyhypusine synthase (DHPS) inhibitor.
1
Cat. No.: HY-W008821
CAS No.: 646-19-5
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1,7-Heptanediamine (C7) is a deoxyhypusine synthase inhibitor with IC50 value of 4.5 μM .
Cat. No.: HY-126171
CAS No.: 34994-11-1
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Hypusine is a natural amino acid. The post-translational synthesis of hypusine is mainly catalyzed by deoxyhypusine synthase (DHPS) and deoxyhypusine hydroxylase (DOHH) .
Cat. No.: HY-108314
CAS No.: 150333-69-0
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GC7 Sulfate is a deoxyhypusine synthase (DHPS) inhibitor.
Cat. No.: HY-P5443
CAS No.: 224569-84-0
Cat. No.: HY-175828
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DHPS-IN-2 is an allosteric deoxyhypusine synthase (DHPS) inhibitor with an IC50 of 70 nM and a Kd of 26.4 μM. DHPS-IN-2 significantly suppresses melanoma cell migration and invasiveness in vitro and exhibits potent anti-tumor efficacy in an A375 cell zebrafish xenograft model. DHPS-IN-2 can be used for the study of melanoma .
Cat. No.: HY-108314AR
CAS No.: 150417-90-6
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GC7 Sulfate (Standard) is the analytical standard of GC7 Sulfate (HY-108314A). This product is intended for research and analytical applications. GC7 Sulfate is a deoxyhypusine synthase (DHPS) inhibitor.
Cat. No.: HY-W141446
CAS No.: 144163-68-8
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VT00065 is a covalent DHS inhibitor. VT00065 forms a redox-dependent covalent bond with the catalytic lysine K329 of DHS, locking the enzyme in an inactive state .
Cat. No.: HY-182529
CAS No.: 2470012-40-7
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DHPS-IN-3 (Compound 26d) is a NAD-competitive DHPS inhibitor, with an IC50 of 0.0092 μM at 14 μM NAD and an IC50 of 0.069 μM at 250 μM NAD. DHPS-IN-3 is applicable for cancer research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
