GC7 Sulfate (Standard)
GC7 Sulfate (Standard) is the analytical standard of GC7 Sulfate (HY-108314A). This product is intended for research and analytical applications. GC7 Sulfate is a deoxyhypusine synthase (DHPS) inhibitor.
For research use only. We do not sell to patients.
- CAS No.: 150417-90-6
- Formula: C8H22N4O4S
- Molecular Weight:270.35
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All DNA/RNA Synthesis Isoforms
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Biological Activity
DHPS[1]
Chemical Information
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CAS No. 150417-90-6
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Molecular Weight 270.35
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Formula C8H22N4O4S
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SMILES
NC(NCCCCCCCN)=N.O=S(O)(O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Bandino A, et al. Deoxyhypusine synthase (DHPS) inhibitor GC7 induces p21/Rb-mediated inhibition of tumor cell growth and DHPS expression correlates with poor prognosis in neuroblastoma patients. Cell Oncol (Dordr). 2014 Dec;37(6):387-98. [Content Brief]
[2]. Lou B, et al. N1-guanyl-1,7-diaminoheptane (GC7) enhances the therapeutic efficacy of doxorubicin by inhibiting activation of eukaryotic translation initiation factor 5A2 (eIF5A2) and preventing the epithelial-mesenchymal transition in hepatocellular carcinoma cells. Exp Cell Res. 2013 Oct 15;319(17):2708-17. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)