DHPS-IN-3
Based on 1 Customer Validation
DHPS-IN-3 (Compound 26d) is a NAD-competitive DHPS inhibitor, with an IC50 of 0.0092 μM at 14 μM NAD and an IC50 of 0.069 μM at 250 μM NAD. DHPS-IN-3 is applicable for cancer research.
For research use only. We do not sell to patients.
- Purity : 97.13%
- CAS No.: 2470012-40-7
- Formula: C18H23N3OS
- Molecular Weight:329.46
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Description
In Vitro
DHPS-IN-3 potently inhibits deoxyhypusine synthase with an IC50 of 0.0092 μM at 14 μM NAD, showing a NAD-competitive inhibitory profile[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Parmacokinetics
Chemical Information
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CAS No. 2470012-40-7
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Appearance Solid
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Molecular Weight 329.46
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Formula C18H23N3OS
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Color Off-white to pink
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SMILES
O=C1C2=C(CCN1[C@@H](CN)CC(C)C)C(C3=CN=CC=C3)=CS2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
In Vitro:
DMSO : ≥ 100 mg/mL (303.53 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (285 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.0353 mL | 15.1763 mL | 30.3527 mL | 75.8817 mL |
| 5 mM | 0.6071 mL | 3.0353 mL | 6.0705 mL | 15.1763 mL | |
| 10 mM | 0.3035 mL | 1.5176 mL | 3.0353 mL | 7.5882 mL | |
| 15 mM | 0.2024 mL | 1.0118 mL | 2.0235 mL | 5.0588 mL | |
| 20 mM | 0.1518 mL | 0.7588 mL | 1.5176 mL | 3.7941 mL | |
| 25 mM | 0.1214 mL | 0.6071 mL | 1.2141 mL | 3.0353 mL | |
| 30 mM | 0.1012 mL | 0.5059 mL | 1.0118 mL | 2.5294 mL | |
| 40 mM | 0.0759 mL | 0.3794 mL | 0.7588 mL | 1.8970 mL | |
| 50 mM | 0.0607 mL | 0.3035 mL | 0.6071 mL | 1.5176 mL | |
| 60 mM | 0.0506 mL | 0.2529 mL | 0.5059 mL | 1.2647 mL | |
| 80 mM | 0.0379 mL | 0.1897 mL | 0.3794 mL | 0.9485 mL | |
| 100 mM | 0.0304 mL | 0.1518 mL | 0.3035 mL | 0.7588 mL |
DHPS-IN-3 Related Classifications
HY-182529 Related Classifications
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