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Results for "

ErbB

" in MedChemExpress (MCE) Product Catalog:

By Targets:	EGFR (127) Adrenergic Receptor (1) Akt (11) Apoptosis (20) Autophagy (22) Bacterial (1) Btk (4) c-Kit (1) c-Met/HGFR (6) C-type Lectin-like Receptors (CTLRs) (1) CD44 (1) CDK (2) CXCR (6) Drug Derivative (1) Drug Metabolite (1) ERK (4) FAK (1) Ferroptosis (16) FGFR (1) FLT3 (1) Glutathione Peroxidase (2) Heme Oxygenase (HO) (2) Histamine Receptor (6) HSP (1) IGF-1R (1) IKK (1) Indoleamine 2,3-Dioxygenase (IDO) (2) Insulin Receptor (1) Isotope-Labeled Compounds (12) Itk (1) JAK (1) Keap1-Nrf2 (2) Ligands for E3 Ligase (1) MAPKAPK2 (MK2) (1) Mitosis (1) mRNA (3) Orthopoxvirus (4) p38 MAPK (6) Paraptosis (1) PARP (1) PDGFR (1) PI3K (2) PI4K (1) PROTACs (1) Raf (1) Ras (1) Reactive Oxygen Species (ROS) (2) Reference Standards (18) Small Interfering RNA (siRNA) (11) Src (4) Survivin (1) TGF-β Receptor (2) Trk Receptor (1) Tyrosine Hydroxylase (1)
By Research Areas:	Cancer (107) Cardiovascular Disease (4) Endocrinology (5) Infection (13) Inflammation/Immunology (18) Metabolic Disease (6) Neurological Disease (9)
Oligonucleotides:	Aptamers (1) Rat Pre-designed siRNA Sets (3) mRNA (3) Mouse Pre-designed siRNA Sets (4) Human Pre-designed siRNA Sets (4) siRNAs (11)

144

Inhibitors & Agonists

Screening Libraries

Peptides

Inhibitory Antibodies

Natural
Products

108

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Oligonucleotides

Targets Recommended: REV-ERB EGFR

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-50898

Lapatinib 90+ Cited Publications GW572016; GW2016	EGFR Autophagy Ferroptosis	Infection Neurological Disease Metabolic Disease Cancer
Lapatinib (GW572016) is a potent, orally active inhibitor of the *ErbB-2* and EGFR tyrosine kinase domains with IC₅₀ values against purified EGFR and *ErbB-2* of 10.2 and 9.8 nM, respectively .

HY-13272

Dacomitinib 25+ Cited Publications PF-00299804; PF-299804	EGFR Apoptosis	Cancer
Dacomitinib (PF-00299804) is a specific and irreversible inhibitor of the *ERBB* family of kinases with IC₅₀s of 6 nM, 45.7 nM and 73.7 nM for EGFR, *ERBB2, and ERBB4*, respectively .

HY-P99275

Patritumab 1 Publications Verification AMG-888; U3-1287	EGFR Akt ERK PARP Survivin	Cancer
Patritumab (Human Anti-ERBB3 Recombinant Antibody) is a neutralizing monoclonal antibody to *ERBB3. Patritumab shows a synergy with Cetuximab (HY-P9905), potently inhibits the phosphorylation of EGFR, HER2, HER3, ERK, and AKT. Patritumab also induces cell apoptosis* and suppresses the growth of pancreatic, non-small cell lung cancer, and colorectal cancer xenograft tumors .

HY-10367

Canertinib 5+ Cited Publications CI-1033; PD-183805	EGFR Orthopoxvirus	Infection Cancer
Canertinib (CI-1033;PD-183805) is a potent and irreversible EGFR inhibitor; inhibits cellular EGFR and *ErbB2* autophosphorylation with IC₅₀s of 7.4 and 9 nM. Canertinib is active against vaccinia virus respiratory infection in mice .

HY-50898A

Lapatinib ditosylate 90+ Cited Publications GW572016 ditosylate; GW2016 ditosylate	EGFR Autophagy Ferroptosis	Infection Neurological Disease Metabolic Disease Cancer
Lapatinib ditosylate (GW572016 ditosylate) is a potent, orally active inhibitor of the *ErbB-2* and EGFR tyrosine kinase domains with IC₅₀ values against purified EGFR and *ErbB-2* of 10.2 and 9.8 nM, respectively .

HY-13050

Sapitinib 15+ Cited Publications AZD-8931	EGFR	Cancer
Sapitinib (AZD-8931) is a reversible, ATP competitive EGFR inhibitor of with IC₅₀s of 4, 3 and 4 nM for EGFR, ErbB2 and ErbB3 in cells, respectively.

HY-P99268

Seribantumab SAR 256212; MM 121; Anti-Human ErbB3/ErbB 3 Recombinant Antibody	EGFR Apoptosis	Cancer
Seribantumab (MM 121) is a fully human IgG2 monoclonal antibody that targets HER3. Seribantumab blocks the activation of epidermal growth factor receptor (ErbB) family members and its downstream signal. Seribantumab inhibits neuregulin 1 (NRG1) fusion-dependent tumorigenesis in vitro and in vivo in breast, lung and ovarian patient-derived cancer models .

HY-50898B

Lapatinib ditosylate monohydrate 90+ Cited Publications GW572016 ditosylate monohydrate; GW2016 ditosylate monohydrate	EGFR Autophagy Ferroptosis	Infection Metabolic Disease Cancer
Lapatinib ditosylate monohydrate (GW572016 ditosylate monohydrate) is a potent, orally active inhibitor of the *ErbB-2* and EGFR tyrosine kinase domains with IC₅₀ values against purified EGFR and *ErbB-2* of 10.2 and 9.8 nM, respectively .

HY-32718

Pelitinib 5+ Cited Publications EKB-569; WAY-EKB 569	EGFR Src	Cancer
Pelitinib (EKB-569;WAY-EKB 569) is an irreversible inhibitor of EGFR with an IC₅₀ of 38.5 nM; also slightly inhibits Src, MEK/ERK and ErbB2 with IC₅₀s of 282, 800, and 1255 nM, respectively.

HY-10045

AEE788 3 Publications Verification NVP-AEE 788	EGFR Apoptosis	Infection Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
AEE788 is an orally active inhibitor targeting EGFR and *ErbB2* with IC₅₀ values of 2 and 6 nM, respectively ^[1][2][3].

HY-10367A

Canertinib dihydrochloride 5+ Cited Publications CI-1033 dihydrochloride; PD-183805 dihydrochloride	EGFR Orthopoxvirus	Infection Cancer
Canertinib dihydrochloride (CI-1033 dihydrochloride) is a potent and irreversible EGFR inhibitor; inhibits cellular EGFR and *ErbB2* autophosphorylation with IC₅₀s of 7.4 and 9 nM. Canertinib dihydrochloride is active against vaccinia virus respiratory infection in mice .

HY-168438

ERBB agonist-1 1 Publications Verification	EGFR Akt ERK	Cardiovascular Disease
ERBB agonist-1 (Compound EF-1) is an agonist for *ERBB4, that activates the ERBB4 signaling pathway by inducing dimerization of the ERBB4 receptor with an EC₅₀* of 10.5 μM. ERBB agonist-1 induces phosphorylation of Akt and ERK1/2, reduces the collagen expression in cardiac fibroblasts, inhibits H₂O₂-induced cardiomyocyte death and Ang II (HY-13948)-induced cardiomyocyte hypertrophy. ERBB agonist-1 prevents fibrosis and exhibits cardioprotective efficacy in mouse models .

HY-P99304

Lumretuzumab Anti-Human ErbB3 Recombinant Antibody	EGFR PI3K Akt p38 MAPK	Cancer
Lumretuzumab (Anti-Human ERBB3 Recombinant Antibody) is a humanized anti-HER3 (ERBB3) monoclonal antibody. Lumretuzumab effectively inhibits the activity of key oncogenic signaling pathways such as PI3K/AKT and MAPK. Lumretuzumab has been optimized through glycosyl engineering to enhance antibody-dependent cell-mediated cytotoxicity (ADCC). Lumretuzumab can be used to study HER3-positive, HER2-low-expressing solid tumors, especially breast cancer .

HY-18609

PD158780 4 Publications Verification	EGFR	Cancer
PD158780 is a potent EGFR family inhibitor with IC₅₀s of 8 pM, 49, 52, 52 nM for EGFR, ErbB2, ErbB3, and ErbB4, respectively.

HY-13427

Allitinib tosylate 2 Publications Verification AST-1306 (TsOH)	EGFR	Cancer
Allitinib tosylate (AST-1306 (TsOH)) is an orally active and irreversible EGFR and *ErbB2* inhibitor with IC₅₀s of 0.5 and 3 nM, respectively. Allitinib tosylate also inhibits *ErbB4* with an IC₅₀ of 0.8 nM. Allitinib tosylate is an anilino-quinazoline compound and has anti-cancer activity

HY-P99672

Istiratumab MM 141; MM-005	IGF-1R EGFR	Cancer
Istiratumab (M-6495) is bispecific monoclonal antibody targeting IGF-1R and *ErbB3. Istiratumab induces IGF-1R and ErbB*3 receptor degradation through the proteasome pathway Istiratumab can be used for research of cancers .

HY-132842A

(S)-Sunvozertinib (S)-DZD9008	EGFR Btk	Cancer
(S)-Sunvozertinib ((S)-DZD9008), the S-enantiomer of Sunvozertinib, shows inhibitory activity against EGFR exon 20 NPH and ASV insertions, EGFR L858R/T790M mutation and Her2 exon20 YVMA insertion (IC₅₀=51.2 nM, 51.9 nM, 1 nM, and 21.2 nM, respectively). (S)-Sunvozertinib also inhibits BTK .

HY-13896

PD168393 3 Publications Verification	EGFR Autophagy Apoptosis	Cancer
PD168393 is a potent, selective and cell-permeable inhibitor of EGFR tyrosine kinase and *ErbB2. PD168393 irreversiblely inactivates EGF receptor ( IC₅₀*=0.7 nM) and is inactive against insulin receptor, PDGFR, FGFR and PKC .

HY-43533

Tarlox-TKI 2 Publications Verification	EGFR	Cancer
Tarlox-TKI, the active metabolite of Tarloxotinib, is an irreversible pan-ErbB TKI (Tarlox-TKI) .

HY-15375

Allitinib 2 Publications Verification AST-1306; ALS 1306	EGFR	Cancer
Allitinib (AST-1306) is an orally active and irreversible EGFR and *ErbB2* inhibitor with IC₅₀s of 0.5 and 3 nM, respectively. Allitinib also inhibits *ErbB4* with an IC₅₀ of 0.8 nM. Allitinib is an anilino-quinazoline compound and has anti-cancer activity .

HY-14674

CP-724714 4 Publications Verification	EGFR Apoptosis	Cancer
CP-724714 is a potent, selective and orally active ErbB2 (HER2) tyrosine kinase inhibitor, with an IC₅₀ of 10 nM. CP-724714 displays a marked selectivity against EGFR kinase (IC₅₀=6400 nM). CP-724714 potently inhibits ErbB2 receptor autophosphorylation in intact cells. Antitumor activities .

HY-20878

Tyrphostin AG 879 3 Publications Verification AG 879	Trk Receptor EGFR Apoptosis	Cancer
Tyrphostin AG 879 (AG 879) is a tyrosine kinase inhibitor that inhibits TrKA phosphorylation (IC₅₀ of 10 μM), but not TrKB and TrKC. Tyrphostin AG 879 is also a selective *ErbB2* tyrosine kinase inhibitor with an IC₅₀ of 1 μM, and has at least 500-fold higher selectivity to *ErbB2* than EGFR. Tyrphostin AG 879 has anticancer activity .

HY-118263

Dacomitinib hydrate 25+ Cited Publications PF-00299804 hydrate; PF-299804 hydrate	EGFR	Cancer
Dacomitinib (PF-00299804) hydrate is an orally active, irreversible pan-ErbB inhibitor. Dacomitinib hydrate can be used in the research of cancers such as metastatic non-small cell lung cancer (NSCLC) .

HY-103443

HKI-357	EGFR	Cancer
HKI-357 is an irreversible dual inhibitor of EGFR and *ERBB2* with IC₅₀s of 34 nM and 33 nM, respectively. HKI-357 suppresses EGFR autophosphorylation (at Y1068), and AKT and MAPK phosphorylation .

HY-103440

*EGFR/ErbB-2/ErbB-4 inhibitor-3*	EGFR	Cancer
EGFR/ErbB-2/ErbB-4 inhibitor-3 (compound 29) is a potent tyrosine kinase inhibitor with IC₅₀s of 0.3, 1.1, 0.5, 2.5, 24 nM for erbB1, erbB2, erbB4, EGF, HER, respectively . EGFR/ErbB-2/ErbB-4 inhibitor-3 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-P4082

ErbB-2-binding peptide HER2-binding peptide	EGFR	Cancer
ErbB-2-binding peptide (HER2-binding peptide) is a tumor-binding peptide. ErbB-2-binding peptide has the potential for cancer research .

HY-116437

Selatinib 1 Publications Verification	EGFR	Cancer
Selatinib is a reversible and orally active dual EGFR and *ErbB2* inhibitor with IC₅₀s of 13 nM and 22.5 nM, respectively. Selatinib has anticancer effects .

HY-E70715

ERBB2 775YVMA776 Recombinant Human Active Protein Kinase	EGFR	Cancer
The erbB family comprises 4 structurally related receptors: ErbB1 (EGFR), ErbB2 (HER2-neu), ErbB3 and ErbB4. On ligand stimulation, the receptor forms either homodimers or heterodimers, which activate their cytoplasmic domain. ERBB2 775YVMA776 Recombinant Human Active Protein Kinase is a recombinant ERBB2 775YVMA776 protein that can be used to study ERBB2 775YVMA776-related functions .

HY-50898S4

Lapatinib-d7 GW572016-d₇; GW2016-d₇	Isotope-Labeled Compounds Autophagy EGFR Ferroptosis	Cancer
Lapatinib-d₇ (GW572016-d₇) is deuterium labeled Lapatinib. Lapatinib (GW572016) is a potent, orally active inhibitor of the *ErbB-2* and EGFR tyrosine kinase domains with IC₅₀ values against purified EGFR and *ErbB-2* of 10.2 and 9.8 nM, respectively .

HY-118532

Tyrphostin AG30 1 Publications Verification AG30	EGFR	Cancer
Tyrphostin AG30 (AG30) is a potent and selective EGFR tyrosine kinase inhibitor. Tyrphostin AG30 (AG30) selectively inhibits self renewal induction by c-ErbB, and is able to inhibit activation of STAT5 by c-ErbB in primary erythroblasts .

HY-100499

Tyrphostin AG 528 1 Publications Verification Tyrphostin B66; AG 528	EGFR	Cancer
Tyrphostin AG 528 is an inhibitor of EGFR and *ErbB2* with IC₅₀s of 4.9 and 2.1 μM, respectively. Tyrphostin AG 528 (Tyrphostin B66) is a protein tyrosine kinase inhibitor, with IC₅₀s of 4.9 μM for epidermal growth factor receptors (EGFR) and 2.1 μM for *ErbB2* . Tyrphostin AG 528 is also an anticancer agent .

HY-P990697

Anvatabart ARX-788	EGFR	Inflammation/Immunology
Anvatabart is an anti-ERBB2 human IgG1 κ monoclonal antibody . Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001).

HY-103441

JNJ28871063 hydrochloride	EGFR	Cancer
JNJ28871063 hydrochloride is an orally active, highly selective and ATP competitive *pan-ErbB* kinase inhibitor with IC₅₀** values of 22 nM, 38 nM, and 21 nM for ErbB1, ErbB2, and ErbB4, respectively. JNJ28871063 hydrochloride inhibits phosphorylation of functionally important tyrosine residues in both EGFR and ErbB2. JNJ28871063 hydrochloride crosses the blood-brain barrier and has antitumor activity in human tumor xenograft models that overexpress EGFR and ErbB2 .

HY-P991240

CDX-3379 KTN-3379	EGFR	Cancer
CDX-3379 is a humanized monoclonal antibody inhibitor targeting *ErbB3. CDX-3379 binds to ErbB3, blocking the dimerization of ErbB3 with other receptors, thereby inhibiting the phosphorylation of ErbB3. CDX-3379 can inhibit the growth and proliferation of tumor cells. CDX-3379 is promising for research of tumors expressing ErbB*3 and NRG1, such as HNSCC .

HY-175809

SRT6	CD44 Src EGFR MAPKAPK2 (MK2)	Cancer
SRT6 is a CD44 inhibitor. SRT6 exerts antiproliferative activity in CD44 ⁺ breast cancer and lung cancer cells. SRT6 inhibits CD44-associated SRC kinase, as well as EGFR, *ERBB2, ERBB4, MAP3K10* and MAPKAPK2. SRT6 can be used for the research of breast cancer and lung cancer .

HY-RS04472

ERBB4 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA) EGFR	Others
ERBB4 Human Pre-designed siRNA Set A contains three designed siRNAs for ERBB4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

ERBB4 Human Pre-designed siRNA Set A ERBB4 Human Pre-designed siRNA Set A

HY-RS04466

ERBB2 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA) EGFR	Others
ERBB2 Human Pre-designed siRNA Set A contains three designed siRNAs for ERBB2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

ERBB2 Human Pre-designed siRNA Set A ERBB2 Human Pre-designed siRNA Set A

HY-50898S1

Lapatinib-d7 dihydrochloride GW572016-d7 dihydrochloride; GW2016-d7 dihydrochloride	Isotope-Labeled Compounds EGFR Autophagy Ferroptosis	Cancer
Lapatinib-d₇ dihydrochloride is the deuterium labeled Lapatinib dihydrochloride. Lapatinib (GW572016) dihydrochloride is a potent, orally active inhibitor of the ErbB-2 and EGFR tyrosine kinase domains with IC₅₀ values against purified EGFR and ErbB-2 of 10.2 and 9.8 nM, respectively .

HY-50898S

Lapatinib-d4 GW572016-d₄; GW2016-d₄	EGFR Autophagy Ferroptosis	Cancer
Lapatinib-d₄ is the deuterium labeled Lapatinib (HY-50898). Lapatinib is a potent, orally active inhibitor of the ErbB-2 and EGFR tyrosine kinase domains with IC₅₀ values against purified EGFR and ErbB-2 of 10.2 and 9.8 nM, respectively .

HY-14347

EBE-A22 1 Publications Verification	EGFR	Cancer
EBE-A22 is a derivative of PD153035, which can inhibit the phosphorylation of ErbB-1, but EBE-A22 does not have this activity.

HY-112420

*EGFR/ErbB-2-IN-2*	EGFR	Infection Metabolic Disease Cancer
EGFR/ErbB-2-IN-2 is a EGFR and *ErbB* inhibitor with IC₅₀s of 0.017 μM, 0.08 μM, 1.91 μM for EGFR, ErbB-2 and ErbB-4 .

HY-P10981

ErbB2 peptide	PI3K Ligands for E3 Ligase	Cancer
ErbB2 peptide is a peptide ligand of E3 ubiquitin ligase targeting PI3K for peptide PROTACs .

HY-153856

TAS2940	EGFR	Cancer
TAS2940 is a brain-penetrable, orally active, irreversible and selective *pan-ERBB* inhibitor. TAS2940 against wild-type HER2, HER2 V777L, and A775_G776insYVMA with IC₅₀ values of 5.6 nM, 2.1 nM, and 1.0 nM, respectively. TAS2940 can be used for the study of tumors with HER2 and EGFR aberrations .

HY-P991524

MM-111	EGFR	Cancer
MM-111 is a bispecific antibody fusion protein targeting the *ErbB2/ErbB3* oncogenic unit. MM-111 blocks activation of the PI3K pro-survival pathway. MM-111 binds to the ErbB2 receptor, which localizes the bispecific molecule to ErbB2 over-expressing tumor cells and promotes binding of the anti-ErbB3 arm to the ErbB3 receptor. MM-111 binding to ErbB3 results in inhibition of ErbB3 signaling by blocking the binding of the ErbB3 physiological ligand heregulin. MM-111 can be used for the study of ErbB2 over-expressing breast tumors .

HY-P991243

MP-RM-1	EGFR Akt	Cancer
MP-RM-1 is an antibody-based, non-competitive *ErbB-3* inhibitor with a K_d value of 32.7 nM. MP-RM-1 inhibits both ligand-dependent and ligand-independent ErbB-3 activation, blocks ErbB-2/ErbB-3 heterodimerization, induces ErbB-3 internalization and degradation, and suppresses the phosphorylation of downstream Akt. MP-RM-1 exerts its antagonistic effect through a non-competitive mechanism. MP-RM-1 inhibits tumor growth in melanoma and prostate cancer xenograft models in nude mice and reduces the proliferative activity of tumor cells .

HY-13272R

Dacomitinib (Standard) PF-00299804 (Standard); PF-299804 (Standard)	Reference Standards EGFR Apoptosis	Cancer
Dacomitinib (Standard) is the analytical standard of Dacomitinib. This product is intended for research and analytical applications. Dacomitinib (PF-00299804) is a specific and irreversible inhibitor of the *ERBB* family of kinases with IC₅₀s of 6 nM, 45.7 nM and 73.7 nM for EGFR, *ERBB2, and ERBB4*, respectively .

HY-P990978

Caxmotabart FS-1502 Antibody; IKS-014 Antibody	EGFR	Inflammation/Immunology
HY-P990978 is an *ERBB2*-targeting IgG1κ type humanized antibody, the recommed isotype control is Human IgG1 kappa, Isotype Control (HY-P99001) .

HY-P990909

Calotatug XMT-1519; XMT-1522 antibody	EGFR	Inflammation/Immunology
HY-P990909 is an *ERBB2*-targeting IgG1κ type human antibody, the recommed isotype control is Human IgG1 kappa, Isotype Control (HY-P99001) .

HY-160068

2-2(t) aptamer sodium	EGFR	Cancer
2-2(t) aptamer sodium is a 42-nucleotide trimeric complex of aptamer (2-2) targeting *ErbB-2*. 2-2(t) aptamer sodium inhibits the growth of gastric cancer cells in vitro and in vivo .

HY-P99558

Timigutuzumab GEXMab73; GT-MAb7.3-GEX; TrastuzuMab-GEX	EGFR	Cancer
Timigutuzumab (GEXMab73) is a humanized monoclonal antibody that targets *ErbB2*. Timigutuzumab can be used for the research of cancer .

Cat. No.	Product Name

HY-L074

Anti-Breast Cancer Compound Library

3,181 compounds

Breast cancer is the most frequent cancer among women, impacting 2.1 million women each year, and also causes the greatest number of cancer-related deaths among women. Surgery is usually the first type of treatment for breast cancer, which is usually followed by chemotherapy or radiotherapy or, in some cases, hormone or targeted therapies, especially for metastatic breast cancer (MBC).

Breast cancer is a heterogeneous disease, which is categorized into 3 major subtypes based on the presence or absence of molecular markers for estrogen or progesterone receptors and human epidermal growth factor 2 (ERBB2; formerly HER2): hormone receptor positive/ERBB2 negative (70% of patients), ERBB2 positive (15%-20%), and triple-negative (tumors lacking all 3 standard molecular markers; 15%). Different intrinsic subtypes exhibit different tumor behavior with different prognoses, and may require specific targeted therapies to maximize treatment effectiveness. Otherwise, some signaling pathways also play important roles in the development of breast cancer, such as NF-κB Signaling Pathway, TGF-beta Signaling Pathway, PI3K/AKT/mTOR signaling pathway and Notch Signaling Pathway. These signaling pathways offer ideal targets for development of new targeted therapies for breast cancer.

MCE supplies a unique collection of 3,181 compounds with identified and potential anti-breast cancer activity. MCE Anti-Breast Cancer Compound Library is a useful tool for anti-breast cancer drugs screening.

Cat. No.	Product Name	Target	Research Area

HY-P4082

ErbB-2-binding peptide HER2-binding peptide	EGFR	Cancer
ErbB-2-binding peptide (HER2-binding peptide) is a tumor-binding peptide. ErbB-2-binding peptide has the potential for cancer research .

HY-P5438

Srctide	Btk c-Kit FAK FLT3 Insulin Receptor	Others
Srctide is a biological active peptide. (This is a peptide substrate for many protein kinases, such as Blk, BTK, cKit, EPHA1, EPHB2, EPHB3, ERBB4, FAK, Flt3, IGF-1R, ITK, Lck, MET, MUSK, Ret, Src, TIE2, TrkB, VEGF-R1 (Flt-1) and VEGF-R2 (KDR).)

HY-P10981

ErbB2 peptide	PI3K Ligands for E3 Ligase	Cancer
ErbB2 peptide is a peptide ligand of E3 ubiquitin ligase targeting PI3K for peptide PROTACs .

HY-P5527F

FAM-CSKtide	Peptides	Others
FAM-CSKtide is a biological active peptide. (This is a FAM labeled peptide substrate (Abs/Em = 494/521 nm) for C-terminal Src kinase (Csk) and many other kinases such as Axl, cKit, ERBB4, Fes, Flt3, IGF-1 R, MET, MUSK, PYK2, Ret, TIE2, TrkA, VEGF-R1 and VEGF-R2.)

Cat. No.	Product Name	Target	Research Area	Image

HY-P99275

Patritumab 1 Publications Verification AMG-888; U3-1287	EGFR Akt ERK PARP Survivin	Cancer
Patritumab (Human Anti-ERBB3 Recombinant Antibody) is a neutralizing monoclonal antibody to *ERBB3. Patritumab shows a synergy with Cetuximab (HY-P9905), potently inhibits the phosphorylation of EGFR, HER2, HER3, ERK, and AKT. Patritumab also induces cell apoptosis* and suppresses the growth of pancreatic, non-small cell lung cancer, and colorectal cancer xenograft tumors .

HY-P99268

Seribantumab SAR 256212; MM 121; Anti-Human ErbB3/ErbB 3 Recombinant Antibody	EGFR Apoptosis	Cancer
Seribantumab (MM 121) is a fully human IgG2 monoclonal antibody that targets HER3. Seribantumab blocks the activation of epidermal growth factor receptor (ErbB) family members and its downstream signal. Seribantumab inhibits neuregulin 1 (NRG1) fusion-dependent tumorigenesis in vitro and in vivo in breast, lung and ovarian patient-derived cancer models .

HY-P99866

Duligotuzumab MEHD-7945A; RG 7597	EGFR	Cancer
Duligotuzumab is a humanized IgG-κ monoclonal antibody targeting EGFR and HER3. It blocks the binding of ligands to these two receptors, inhibits the downstream HER/ErbB, AKT and MAPK signaling pathways, induces antibody-dependent cell-mediated cytotoxicity, reduces the proliferation and migration abilities of cancer cells, promotes cell apoptosis, exerts a radiosensitizing effect, and reverses EGFR resistance in cancer cells. Duligotuzumab can be used in tumor-related research .

HY-P99304

Lumretuzumab Anti-Human ErbB3 Recombinant Antibody	EGFR PI3K Akt p38 MAPK	Cancer
Lumretuzumab (Anti-Human ERBB3 Recombinant Antibody) is a humanized anti-HER3 (ERBB3) monoclonal antibody. Lumretuzumab effectively inhibits the activity of key oncogenic signaling pathways such as PI3K/AKT and MAPK. Lumretuzumab has been optimized through glycosyl engineering to enhance antibody-dependent cell-mediated cytotoxicity (ADCC). Lumretuzumab can be used to study HER3-positive, HER2-low-expressing solid tumors, especially breast cancer .

HY-P99672

Istiratumab MM 141; MM-005	IGF-1R EGFR	Cancer
Istiratumab (M-6495) is bispecific monoclonal antibody targeting IGF-1R and *ErbB3. Istiratumab induces IGF-1R and ErbB*3 receptor degradation through the proteasome pathway Istiratumab can be used for research of cancers .

HY-P990697

Anvatabart ARX-788	EGFR	Inflammation/Immunology
Anvatabart is an anti-ERBB2 human IgG1 κ monoclonal antibody . Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001).

HY-P991240

CDX-3379 KTN-3379	EGFR	Cancer
CDX-3379 is a humanized monoclonal antibody inhibitor targeting *ErbB3. CDX-3379 binds to ErbB3, blocking the dimerization of ErbB3 with other receptors, thereby inhibiting the phosphorylation of ErbB3. CDX-3379 can inhibit the growth and proliferation of tumor cells. CDX-3379 is promising for research of tumors expressing ErbB*3 and NRG1, such as HNSCC .

HY-P991524

MM-111	EGFR	Cancer
MM-111 is a bispecific antibody fusion protein targeting the *ErbB2/ErbB3* oncogenic unit. MM-111 blocks activation of the PI3K pro-survival pathway. MM-111 binds to the ErbB2 receptor, which localizes the bispecific molecule to ErbB2 over-expressing tumor cells and promotes binding of the anti-ErbB3 arm to the ErbB3 receptor. MM-111 binding to ErbB3 results in inhibition of ErbB3 signaling by blocking the binding of the ErbB3 physiological ligand heregulin. MM-111 can be used for the study of ErbB2 over-expressing breast tumors .

HY-P991243

MP-RM-1	EGFR Akt	Cancer
MP-RM-1 is an antibody-based, non-competitive *ErbB-3* inhibitor with a K_d value of 32.7 nM. MP-RM-1 inhibits both ligand-dependent and ligand-independent ErbB-3 activation, blocks ErbB-2/ErbB-3 heterodimerization, induces ErbB-3 internalization and degradation, and suppresses the phosphorylation of downstream Akt. MP-RM-1 exerts its antagonistic effect through a non-competitive mechanism. MP-RM-1 inhibits tumor growth in melanoma and prostate cancer xenograft models in nude mice and reduces the proliferative activity of tumor cells .

HY-P990978

Caxmotabart FS-1502 Antibody; IKS-014 Antibody	EGFR	Inflammation/Immunology
HY-P990978 is an *ERBB2*-targeting IgG1κ type humanized antibody, the recommed isotype control is Human IgG1 kappa, Isotype Control (HY-P99001) .

HY-P990909

Calotatug XMT-1519; XMT-1522 antibody	EGFR	Inflammation/Immunology
HY-P990909 is an *ERBB2*-targeting IgG1κ type human antibody, the recommed isotype control is Human IgG1 kappa, Isotype Control (HY-P99001) .

HY-P99558

Timigutuzumab GEXMab73; GT-MAb7.3-GEX; TrastuzuMab-GEX	EGFR	Cancer
Timigutuzumab (GEXMab73) is a humanized monoclonal antibody that targets *ErbB2*. Timigutuzumab can be used for the research of cancer .

HY-P991244

REGN-1400	EGFR	Cancer
REGN-1400 is a humanized monoclonal antibody inhibitor targeting *ErbB3. REGN-1400 reduces tumor cell proliferation by inhibiting ErbB*3 and blocking related signaling pathways. REGN-1400 is promising for research of solid tumors such as non-small cell lung cancer (NSCLC), colorectal cancer (CRC), and squamous cell carcinoma of the head and neck (SCCHN) .

HY-P991159

Ruzaltatug	EGFR	Cancer
Ruzaltatug is a humanized IgG1 antibody targeting *ERBB3*. The corresponding isotype control is: Human IgG1 kappa, Isotype Control (HY-P99001) .

HY-P991241

*Anti-ERBB3/HER3 (29Z6)*	EGFR	Cancer
Anti-ERBB3/HER3 (29Z6) is an antibody inhibitor, targeting to human ERBB3/HER3.

HY-P991245

*Anti-ERBB3/HER3 (SGP1)*	EGFR	Cancer
Anti-ERBB3/HER3 (SGP1) is a human monoclonal antibody (mAb) targeting *ERBB3/HER3. Anti-ERBB3/HER3 (SGP1) inhibits Neuregulin stimulated growth of cultured breast cancer cells. Anti-ERBB*3/HER3 (SGP1) can be used in breast cancer research .

HY-P990408

*Anti-ERBB1/EGFR/HER1 Antibody*	EGFR	Inflammation/Immunology
The Anti-ERBB1/EGFR/HER1 Antibody is a CHO-expressed human antibody that targets *ERBB1/EGFR/HER1. The Anti-ERBB1/EGFR/HER1 Antibody consists of a huIgG1 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 145 kDa. The isotype control for the Anti-ERBB*1/EGFR/HER1 Antibody can refer to Human IgG1 kappa, Isotype Control (HY-P99001).

HY-P990409

*Anti-ERBB1/EGFR/HER1 Antibody (7A7)*	Inhibitory Antibodies	Inflammation/Immunology
Anti-ERBB1/EGFR/HER1 Antibody (7A7) is a human-derived antibody expressed in CHO cells, targeting *ERBB1/EGFR/HER1. Anti-ERBB1/EGFR/HER1 Antibody (7A7) has a muIgG1 heavy chain and an mκ light chain, with a predicted molecular weight (MW) of 150 kDa. The isotype control for Anti-ERBB*1/EGFR/HER1 Antibody (7A7) can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001).

HY-P990972

Azerutamig	EGFR	Inflammation/Immunology
HY-P990972 is an *KLRK1/ERBB2*-targeting (H-γ1_L-κ)_scFvkh-H-γ1(h-CH2-CH3) type bispecific antibody .

HY-P990596

Hersintuzumab	Inhibitory Antibodies	Inflammation/Immunology
Hersintuzumab is a CHO-expressed humanized antibody targeting *ERBB2/HER2/CD340*. Hersintuzumab is equipped with a huIgG1 heavy chain and huκ light chain, with a predicted molecular weight (MW) of 150 kDa. The isotype control for Hersintuzumab can refer to Human IgG1 kappa, Isotype Control (HY-P99001).

HY-P990695

Lunaxafusp	EGFR	Inflammation/Immunology
Lunaxafusp is an anti-ERBB2 scFv-heavy-κ monoclonal antibody composed of a single chain variable fragment, an antibody heavy chain, and a kappa antibody light chain .

HY-P991979

Erbicin	EGFR	Cancer
Erbicin is a single-chain antibody against the human *ErbB2* receptor . Erbicin specifically binds to ErbB2-positive cells, inhibits receptor autophosphorylation, and is internalized by target cells. Erbicin can be used in breast cancer-related research .

HY-P992138

Vadalentamig	EGFR C-type Lectin-like Receptors (CTLRs)	Others
Vadalentamig is a human-derived bispecific antibody targeting *NKG2D/CD314&ERBB1/EGFR/HER1* .

HY-P992128

Rinumafusp alfa	EGFR	Others
Rinumafusp alfa is a human monoclonal antibody targeting *ERBB3/HER3*. The corresponding isotype control is: Human IgG1 kappa, Isotype Control (HY-P99001).

HY-P992107

Dulpatatug	EGFR	Cancer
Dulpatatug is a monoclonal antibody targeting *ERBB2*, which can be used for research on gastric cancer, breast cancer and non-small cell lung cancer.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N0353

Curdione 2 Publications Verification (+)-Curdione	Structural Classification Classification of Application Fields Terpenoids Sesquiterpenes Other Diseases Curcuma phaeocaulis Valeton Plants Disease Research Fields Source Classification Zingiberaceae	Ferroptosis Apoptosis Reactive Oxygen Species (ROS) Autophagy Glutathione Peroxidase Keap1-Nrf2 Heme Oxygenase (HO) TGF-β Receptor Indoleamine 2,3-Dioxygenase (IDO)
Curdione ((+)-Curdione) is an orally active sesquiterpenoid. Curdione inhibits platelet aggregation. Curdione induces ferroptosis in colorectal cancer via m6A methylation mediated by METTL14 and YTHDF2. Curdione inhibits ferroptosis in Isoproterenol (HY-B0468)-induced myocardial infarction by regulating the Keap1/Trx1/GPX4 signaling pathway, suppressing oxidative stress (ROS) and apoptosis. Curdione ameliorates Doxorubicin (HY-15142)-induced cardiotoxicity by inhibiting oxidative stress (ROS) and activating the Nrf2/HO-1 pathway. Curdione ameliorates sepsis-induced lung injury by inhibiting platelet-mediated neutrophil extracellular trap formation. Curdione ameliorates Bleomycin (HY-17565A)-induced pulmonary fibrosis by inhibiting TGF-β-induced fibroblast-to-myofibroblast differentiation. Curdione exhibits neuroprotective effects against focal cerebral ischemia-reperfusion injury in rats. Curdione exerts antiproliferative effects against human uterine leiomyosarcoma by targeting IDO1. Curdione protects vascular endothelial cells and atherosclerosis by regulating DNMT1-mediated ERBB4 promoter methylation. Curdione inhibits inducible prostaglandin E2 production (IC₅₀ = 1.1 μM) and cyclooxygenase 2 expression .

HY-B0426A

Olopatadine hydrochloride ALO4943A; KW4679	Structural Classification Alkaloids Classification of Application Fields Ketones, Aldehydes, Acids Other Alkaloids Endogenous metabolite Inflammation/Immunology Disease Research Fields Source Classification	Histamine Receptor CXCR
Olopatadine hydrochloride (ALO4943A; KW4679) is an orally active histamine H1 receptor antagonist and mast cell stabilizer. Olopatadine hydrochloride exerts antiallergic effects by blocking histamine H1 receptor-mediated activities. Olopatadine hydrochloride inhibits exocytosis, chemokine release, F-actin polymerization, CXCL10-induced calcium influx, and T cell chemotactic activity. Olopatadine hydrochloride also reduces the expression levels of CXCR3 on the surface of CD4 ⁺ and CD8 ⁺ T cells. Olopatadine hydrochloride inhibits scratching behavior, improves dermatitis scores, and suppresses intraepidermal neurite outgrowth. Olopatadine hydrochloride simultaneously decreases the levels of inflammatory markers, growth factors, histamine, and specific IgE, while increasing the expression of *ErbB3A/HER3A*. Olopatadine hydrochloride can be used in research related to seasonal pollinosis, chronic rhinitis, urticaria, allergic conjunctivitis, alopecia areata, and atopic dermatitis .

HY-W062109

Olopatadine	Structural Classification Alkaloids Classification of Application Fields Other Alkaloids Endogenous metabolite Inflammation/Immunology Disease Research Fields Source Classification	Histamine Receptor CXCR
Olopatadine (ALO4943A; KW4679) is an orally active histamine H1 receptor antagonist and mast cell stabilizer. Olopatadine exerts antiallergic effects by blocking histamine H1 receptor-mediated activities. Olopatadine inhibits exocytosis, chemokine release, F-actin polymerization, CXCL10-induced calcium influx, and T cell chemotactic activity. Olopatadine also reduces the expression levels of CXCR3 on the surface of CD4 ⁺ and CD8 ⁺ T cells. Olopatadine inhibits scratching behavior, improves dermatitis scores, and suppresses intraepidermal neurite outgrowth. Olopatadine simultaneously decreases the levels of inflammatory markers, growth factors, histamine, and specific IgE, while increasing the expression of *ErbB3A/HER3A*. Olopatadine can be used in research related to seasonal pollinosis, chronic rhinitis, urticaria, allergic conjunctivitis, alopecia areata, and atopic dermatitis .

HY-N1166

Tephrosin 3 Publications Verification Deguelinol I; Hydroxydeguelin	Flavonoids Ranunculus japonicus Thunb. Classification of Application Fields Isoflavanones Ranunculaceae Plants Disease Research Fields Source Classification Cancer	EGFR
Tephrosin is a natural rotenoid which has potent antitumor activities. Tephrosin induces degradation of of EGFR and *ErbB2* by inducing internalization of the receptors .

HY-B0426AR

Olopatadine hydrochloride (Standard) ALO4943A (Standard); KW4679 (Standard)	Structural Classification Alkaloids Ketones, Aldehydes, Acids Other Alkaloids Endogenous metabolite Source Classification	Reference Standards Histamine Receptor CXCR
Olopatadine (hydrochloride) (Standard) is the analytical standard of Olopatadine (hydrochloride). This product is intended for research and analytical applications. Olopatadine hydrochloride (ALO4943A; KW4679) is an orally active histamine H1 receptor antagonist and mast cell stabilizer. Olopatadine hydrochloride exerts antiallergic effects by blocking histamine H1 receptor-mediated activities. Olopatadine hydrochloride inhibits exocytosis, chemokine release, F-actin polymerization, CXCL10-induced calcium influx, and T cell chemotactic activity. Olopatadine hydrochloride also reduces the expression levels of CXCR3 on the surface of CD4 ⁺ and CD8 ⁺ T cells. Olopatadine hydrochloride inhibits scratching behavior, improves dermatitis scores, and suppresses intraepidermal neurite outgrowth. Olopatadine hydrochloride simultaneously decreases the levels of inflammatory markers, growth factors, histamine, and specific IgE, while increasing the expression of *ErbB3A/HER3A*. Olopatadine hydrochloride can be used in research related to seasonal pollinosis, chronic rhinitis, urticaria, allergic conjunctivitis, alopecia areata, and atopic dermatitis .

HY-N0353R

Curdione (Standard) (+)-Curdione (Standard)	Structural Classification Terpenoids Sesquiterpenes Curcuma phaeocaulis Valeton Plants Source Classification Zingiberaceae	Reference Standards Ferroptosis Apoptosis Reactive Oxygen Species (ROS) Autophagy Glutathione Peroxidase Keap1-Nrf2 Heme Oxygenase (HO) TGF-β Receptor Indoleamine 2,3-Dioxygenase (IDO)
Curdione (Standard) is the analytical standard of Curdione. This product is intended for research and analytical applications. Curdione ((+)-Curdione) is an orally active sesquiterpenoid. Curdione inhibits platelet aggregation. Curdione induces ferroptosis in colorectal cancer via m6A methylation mediated by METTL14 and YTHDF2. Curdione inhibits ferroptosis in Isoproterenol (HY-B0468)-induced myocardial infarction by regulating the Keap1/Trx1/GPX4 signaling pathway, suppressing oxidative stress (ROS) and apoptosis. Curdione ameliorates Doxorubicin (HY-15142)-induced cardiotoxicity by inhibiting oxidative stress (ROS) and activating the Nrf2/HO-1 pathway. Curdione ameliorates sepsis-induced lung injury by inhibiting platelet-mediated neutrophil extracellular trap formation. Curdione ameliorates Bleomycin (HY-17565A)-induced pulmonary fibrosis by inhibiting TGF-β-induced fibroblast-to-myofibroblast differentiation. Curdione exhibits neuroprotective effects against focal cerebral ischemia-reperfusion injury in rats. Curdione exerts antiproliferative effects against human uterine leiomyosarcoma by targeting IDO1. Curdione protects vascular endothelial cells and atherosclerosis by regulating DNMT1-mediated ERBB4 promoter methylation. Curdione inhibits inducible prostaglandin E2 production (IC₅₀ = 1.1 μM) and cyclooxygenase 2 expression .

Species:	Human (69) Rhesus Macaque (9) Rat (9) Mouse (12) Cynomolgus (7) Canine (2)
Tag:	His (71) Strep (7) Tag Free (4) Avi (22) Myc (1) GST (13) Fc (29)
Source:	HEK293 (87) sf9 insect cells (5) CHO (1) Sf9 insect cells (13) E. coli (2)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P78435

	EGFR Protein, Human (HEK293, His-Avi) ErbB; EC 2.7.10; EC 2.7.10.1; EGFR; mENA; LEGFR; ErbB; ErbB1; HER1; PIG61; NISBD2	Human	HEK293
	The EGFR protein is a receptor tyrosine kinase that can bind to a variety of ligands, such as EGF, TGFA, AREG, epigen, BTC, epiregulin, and HBEGF, to initiate signaling cascades that mediate cellular responses. This involves receptor dimerization, autophosphorylation and recruitment of adapter proteins such as GRB2, activating downstream pathways such as RAS-RAF-MEK-ERK, PI3-kinase-AKT, PLCgamma-PKC and STAT. EGFR Protein, Human (HEK293, His-Avi) is the recombinant human-derived EGFR protein, expressed by HEK293 , with C-Avi, C-His labeled tag.

HY-P78432

	EGFR vIII Protein, Human (HEK293, His-Avi) ErbB; EC 2.7.10; EC 2.7.10.1; EGFR; mENA; LEGFR; ErbB; ErbB1; HER1; PIG61; NISBD2	Human	HEK293
	The EGFR protein is a receptor tyrosine kinase that can bind to a variety of ligands, such as EGF, TGFA, AREG, epigen, BTC, epiregulin, and HBEGF, to initiate signaling cascades that mediate cellular responses. This involves receptor dimerization, autophosphorylation and recruitment of adapter proteins such as GRB2, activating downstream pathways such as RAS-RAF-MEK-ERK, PI3-kinase-AKT, PLCgamma-PKC and STAT. EGFR vIII Protein, Human (HEK293, His-Avi) is the recombinant human-derived EGFR vIII protein, expressed by HEK293 , with N-Avi, N-His labeled tag.

HY-P78436

	FITC-Labeled EGFR Protein, Human (HEK293, His-Avi) ErbB; EC 2.7.10; EC 2.7.10.1; EGFR; mENA; LEGFR; ErbB; ErbB1; HER1; PIG61; NISBD2	Human	HEK293
	The EGFR protein is a receptor tyrosine kinase that can bind to a variety of ligands, such as EGF, TGFA, AREG, epigen, BTC, epiregulin, and HBEGF, to initiate signaling cascades that mediate cellular responses. This involves receptor dimerization, autophosphorylation and recruitment of adapter proteins such as GRB2, activating downstream pathways such as RAS-RAF-MEK-ERK, PI3-kinase-AKT, PLCgamma-PKC and STAT. EGFR Protein, Human (FITC, HEK293, His-Avi) is the recombinant human-derived EGFR protein, expressed by HEK293 , with C-Avi, C-His labeled tag.

HY-P705474

	FITC-Labeled EGFR vIII Protein, Human (HEK293, His) ErbB; EC 2.7.10; EC 2.7.10.1; EGFR; mENA; LEGFR; ErbB; ErbB1; HER1; PIG61; NISBD2	Human	HEK293

HY-P78433

	FITC-Labeled EGFR vIII Protein, Human (HEK293, His-Avi) ErbB; EC 2.7.10; EC 2.7.10.1; EGFR; mENA; LEGFR; ErbB; ErbB1; HER1; PIG61; NISBD2	Human	HEK293
	The EGFR protein is a receptor tyrosine kinase that can bind to a variety of ligands, such as EGF, TGFA, AREG, epigen, BTC, epiregulin, and HBEGF, to initiate signaling cascades that mediate cellular responses. This involves receptor dimerization, autophosphorylation and recruitment of adapter proteins such as GRB2, activating downstream pathways such as RAS-RAF-MEK-ERK, PI3-kinase-AKT, PLCgamma-PKC and STAT. EGFR vIII Protein, Human (FITC, HEK293, His-Avi) is the recombinant human-derived EGFR vIII protein, expressed by HEK293 , with C-Avi, C-His labeled tag.

HY-P78118

	EGFR Protein, Human (Biotinylated, HEK293, His-Avi) ErbB; EC 2.7.10; EC 2.7.10.1; EGFR; mENA; LEGFR; ErbB; ErbB1; HER1; PIG61; NISBD2	Human	HEK293
	The EGFR protein is a receptor tyrosine kinase that can bind to a variety of ligands, such as EGF, TGFA, AREG, epigen, BTC, epiregulin, and HBEGF, to initiate signaling cascades that mediate cellular responses. This involves receptor dimerization, autophosphorylation and recruitment of adapter proteins such as GRB2, activating downstream pathways such as RAS-RAF-MEK-ERK, PI3-kinase-AKT, PLCgamma-PKC and STAT. EGFR Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived EGFR protein, expressed by HEK293 , with C-Avi, C-His labeled tag.

HY-P704578

	EGFR Protein, Human (621a.a, HEK293) Epidermal growth factor receptor; EGFR; ErbB; ErbB1; HER1	Human	HEK293
	The EGFR protein is a receptor tyrosine kinase that can bind to a variety of ligands, such as EGF, TGFA, AREG, epigen, BTC, epiregulin, and HBEGF, to initiate signaling cascades that mediate cellular responses. This involves receptor dimerization, autophosphorylation and recruitment of adapter proteins such as GRB2, activating downstream pathways such as RAS-RAF-MEK-ERK, PI3-kinase-AKT, PLCgamma-PKC and STAT. EGFR Protein, Human (621a.a, HEK293) is the recombinant human-derived EGFR protein, expressed by HEK293, with tag free.

HY-P78434

	PE-Labeled EGFR vIII Protein, Human (HEK293, His-Avi) ErbB; EC 2.7.10; EC 2.7.10.1; EGFR; mENA; LEGFR; ErbB; ErbB1; HER1; PIG61; NISBD2	Human	HEK293
	The EGFR protein is a receptor tyrosine kinase that can bind to a variety of ligands, such as EGF, TGFA, AREG, epigen, BTC, epiregulin, and HBEGF, to initiate signaling cascades that mediate cellular responses. This involves receptor dimerization, autophosphorylation and recruitment of adapter proteins such as GRB2, activating downstream pathways such as RAS-RAF-MEK-ERK, PI3-kinase-AKT, PLCgamma-PKC and STAT. PE-Labeled EGFR vIII Protein, Human (HEK293, His-Avi) is the recombinant human-derived EGFR vIII protein, expressed by HEK293 , with C-Avi, C-His labeled tag.

HY-P704197

	EGFR Protein, Human (Active, L861Q, sf9, GST) Epidermal growth factor receptor; EGFR; ErbB; ErbB1; HER1	Human	Sf9 insect cells
	The EGFR protein is a receptor tyrosine kinase that can bind to a variety of ligands, such as EGF, TGFA, AREG, epigen, BTC, epiregulin, and HBEGF, to initiate signaling cascades that mediate cellular responses. This involves receptor dimerization, autophosphorylation and recruitment of adapter proteins such as GRB2, activating downstream pathways such as RAS-RAF-MEK-ERK, PI3-kinase-AKT, PLCgamma-PKC and STAT. EGFR Protein, Human (L861Q, sf9, GST) is the recombinant human-derived EGFR protein, expressed by Sf9 insect cells, with N-GST labeled tag.

HY-P704576

	EGFR Protein, Human (621a.a, HEK293, Llama Fc) Epidermal growth factor receptor; EGFR; ErbB; ErbB1; HER1	Human	HEK293
	The EGFR protein is a receptor tyrosine kinase that can bind to a variety of ligands, such as EGF, TGFA, AREG, epigen, BTC, epiregulin, and HBEGF, to initiate signaling cascades that mediate cellular responses. This involves receptor dimerization, autophosphorylation and recruitment of adapter proteins such as GRB2, activating downstream pathways such as RAS-RAF-MEK-ERK, PI3-kinase-AKT, PLCgamma-PKC and STAT. EGFR Protein, Human (621a.a, HEK293, Llama Fc) is the recombinant human-derived EGFR protein, expressed by HEK293, with C-Llama Fc labeled tag.

HY-P70613

	EGFR Protein, Human (621a.a, HEK293, His) Epidermal growth factor receptor; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase ErbB-1; EGFR; ErbB; ErbB1; HER1	Human	HEK293
	The EGFR protein is a receptor tyrosine kinase that can bind to a variety of ligands, such as EGF, TGFA, AREG, epigen, BTC, epiregulin, and HBEGF, to initiate signaling cascades that mediate cellular responses. This involves receptor dimerization, autophosphorylation and recruitment of adapter proteins such as GRB2, activating downstream pathways such as RAS-RAF-MEK-ERK, PI3-kinase-AKT, PLCgamma-PKC and STAT. EGFR Protein, Human (621a.a, HEK293, His) is the recombinant human-derived EGFR protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P70608

	EGFR vIII Protein, Human (HEK293, Fc) 1 Publications Verification Epidermal growth factor receptor; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase ErbB-1; EGFR; ErbB; ErbB1; HER1	Human	HEK293
	The EGFR vIII protein is a transmembrane glycoprotein in the protein kinase superfamily that acts as a receptor for epidermal growth factor. It acts on the cell surface, binds to epidermal growth factor, triggers receptor dimerization and tyrosine autophosphorylation, and promotes cell proliferation. EGFR vIII Protein, Human (HEK293, Fc) is the recombinant human-derived EGFR vIII protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P704574

	FITC-Labeled EGFR Protein, Human (621a.a, HEK293, His) Epidermal growth factor receptor; EGFR; ErbB; ErbB1; HER1	Human	HEK293
	The EGFR protein is a receptor tyrosine kinase that can bind to a variety of ligands, such as EGF, TGFA, AREG, epigen, BTC, epiregulin, and HBEGF, to initiate signaling cascades that mediate cellular responses. This involves receptor dimerization, autophosphorylation and recruitment of adapter proteins such as GRB2, activating downstream pathways such as RAS-RAF-MEK-ERK, PI3-kinase-AKT, PLCgamma-PKC and STAT. FITC-Labeled EGFR Protein, Human (621a.a, HEK293, His) is the recombinant human-derived FITC-Labeled EGFR protein, expressed by HEK293, with C-His labeled tag.

HY-P705815

	EGFR Protein, Human (Active, G719C, sf9, His-GST) Epidermal growth factor receptor; EGFR; ErbB; ErbB1; HER1	Human	sf9 insect cells

HY-P78117

	EGFR vIII Protein, Human (Biotinylated, HEK293, His-Avi) ErbB; EC 2.7.10; EC 2.7.10.1; EGFR; mENA; LEGFR; ErbB; ErbB1; HER1; PIG61; NISBD2	Human	HEK293
	The EGFRvIII protein is a transmembrane glycoprotein in the protein kinase superfamily that acts as a receptor for epidermal growth factor. It acts on the cell surface, binds to epidermal growth factor, triggers receptor dimerization and tyrosine autophosphorylation, and promotes cell proliferation. EGFR vIII Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived EGFR vIII protein, expressed by HEK293 , with C-Avi, C-His labeled tag.

HY-P705811

	EGFR Protein, Human (Active, G719S, sf9, Strep-GST, His) Epidermal growth factor receptor; EGFR; ErbB; ErbB1; HER1	Human	sf9 insect cells

HY-P705562

	EGFR Protein, Human (Active, L858R, sf9, His) Epidermal growth factor receptor; EGFR; ErbB; ErbB1; HER1; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase ErbB-1; EC:2.7.10.1	Human	Sf9 insect cells

HY-P701267

	FITC-labeled EGFR Protein, Human (HEK293, Fc) EGFR; ErbB; ErbB1; HER1; PIG61; mENA	Human	HEK293
	The EGFR protein is a receptor tyrosine kinase that can bind to a variety of ligands, such as EGF, TGFA, AREG, epigen, BTC, epiregulin, and HBEGF, to initiate signaling cascades that mediate cellular responses. This involves receptor dimerization, autophosphorylation and recruitment of adapter proteins such as GRB2, activating downstream pathways such as RAS-RAF-MEK-ERK, PI3-kinase-AKT, PLCgamma-PKC and STAT. FITC-labeled EGFR Protein, Human (HEK293, Fc) is the recombinant human-derived FITC-labeled EGFR protein, expressed by HEK293 , with Fc labeled tag.

HY-P705812

	EGFR Protein, Human (Active, A763_Y764insFHEA, sf9, Strep-GST, His) Epidermal growth factor receptor; EGFR; ErbB; ErbB1; HER1	Human	sf9 insect cells

HY-P705813

	EGFR Protein, Human (Active, A763_Y764insFQEA, sf9, Strep-GST, His) Epidermal growth factor receptor; EGFR; ErbB; ErbB1; HER1	Human	sf9 insect cells

HY-P700409

	EGFR Protein, Human (621a.a, HEK293, N-His, C-Myc) Epidermal growth factor receptor; EGFR; ErbB; ErbB1; HER1	Human	HEK293
	The EGFR protein is a receptor tyrosine kinase that can bind to a variety of ligands, such as EGF, TGFA, AREG, epigen, BTC, epiregulin, and HBEGF, to initiate signaling cascades that mediate cellular responses. This involves receptor dimerization, autophosphorylation and recruitment of adapter proteins such as GRB2, activating downstream pathways such as RAS-RAF-MEK-ERK, PI3-kinase-AKT, PLCgamma-PKC and STAT. EGFR Protein, Human (621a.a, HEK293, N-His, C-Myc) is the recombinant human-derived EGFR protein, expressed by HEK293 , with C-Myc, N-10*His labeled tag.

HY-P702831

	EGFR Protein, Human (Active, C797S, T790M, L858R, sf9, GST) Epidermal growth factor receptor; EGFR; ErbB; ErbB1; HER1	Human	Sf9 insect cells
	The EGFR protein is a receptor tyrosine kinase that can bind to a variety of ligands, such as EGF, TGFA, AREG, epigen, BTC, epiregulin, and HBEGF, to initiate signaling cascades that mediate cellular responses. This involves receptor dimerization, autophosphorylation and recruitment of adapter proteins such as GRB2, activating downstream pathways such as RAS-RAF-MEK-ERK, PI3-kinase-AKT, PLCgamma-PKC and STAT. EGFR Protein, Human (C797S, T790M, L858R, sf9, GST) is the recombinant human-derived EGFR, expressed by Sf9 insect cells, with N-GST labeled tag.

HY-P702832

	EGFR Protein, Human (Active, T790M, L858R, sf9, Strep II, GST, His) Epidermal growth factor receptor; EGFR; ErbB; ErbB1; HER1	Human	Sf9 insect cells
	The EGFR protein is a receptor tyrosine kinase that can bind to a variety of ligands, such as EGF, TGFA, AREG, epigen, BTC, epiregulin, and HBEGF, to initiate signaling cascades that mediate cellular responses. This involves receptor dimerization, autophosphorylation and recruitment of adapter proteins such as GRB2, activating downstream pathways such as RAS-RAF-MEK-ERK, PI3-kinase-AKT, PLCgamma-PKC and STAT. EGFR Protein, Human (T790M, L858R, sf9, Strep II, GST, His) is the recombinant human-derived EGFR, expressed by Sf9 insect cells, with C-8*His, N-GST, N-Strep II labeled tag.

HY-P705601

	EGFR Protein, Human (Active, ΔE746-A750, T790M, L858R, sf9, GST) Epidermal growth factor receptor; EGFR; ErbB; ErbB1; HER1	Human	Sf9 insect cells

HY-P705561

	EGFR Protein, Human (Active, ΔE746-A750, T790M, C797S, sf9, Strep-GST, His) Epidermal growth factor receptor; EGFR; ErbB; ErbB1; HER1; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase ErbB-1; EC:2.7.10.1	Human	Sf9 insect cells

HY-P705814

	EGFR Protein, Human (Active, G696-G1022, ΔE746-A750, T790M, C797S, sf9, Strep-GST, His) Epidermal growth factor receptor; EGFR; ErbB; ErbB1; HER1	Human	sf9 insect cells

HY-P72986

	EGFR Protein, Canine (sf9, His) Epidermal growth factor receptor; EGFR; ErbB; ErbB1; HER1	Canine	Sf9 insect cells
	EGFR Protein is a receptor tyrosine kinase that binds to ligands of the EGF family. The high expression of EGFR protein can be used as a diagnostic marker for canine transitional cell carcinoma (TCC). EGFR Protein participate in the NF-kappa-B signaling pathway. The high expression of EGFR protein can be used as a diagnostic marker for canine transitional cell carcinoma (TCC). EGFR Protein, Canine (sf9, His) is the recombinant canine-derived EGFR protein, expressed by Sf9 insect cells , with C-His labeled tag.

HY-P72988

	EGFR Protein, Mouse (HEK293, Fc) Epidermal growth factor receptor; EGFR; ErbB; ErbB1; HER1	Mouse	HEK293
	The EGFR protein is a receptor tyrosine kinase that binds EGF family ligands and activates multiple signaling cascades. Ligand binding induces receptor homo- or heterodimerization, leading to autophosphorylation and recruitment of adapter proteins (such as GRB2). EGFR Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived EGFR protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P72990

	EGFR Protein, Rat (HEK293, His) Epidermal growth factor receptor; EGFR; ErbB; ErbB1; HER1	Rat	HEK293
	EGFR Protein is a receptor tyrosine kinase that binds to ligands of the EGF family.EGFR Protein is involved in the regulation of NF-kappa-B , RAS-RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs signaling pathways.EGFR Protein has calmodulin binding activity, epidermal growth factor binding activity and epidermal growth factor activating receptor activity.EGFR Protein, Rat (HEK293, His) is the recombinant rat-derived EGFR protein, expressed by HEK293 , with C-His labeled tag.

HY-P72989

	EGFR Protein, Mouse (HEK293, His, solution) 1 Publications Verification Epidermal growth factor receptor; EGFR; ErbB; ErbB1; HER1	Mouse	HEK293
	The EGFR protein is a receptor tyrosine kinase that binds EGF family ligands and activates multiple signaling cascades. Ligand binding induces receptor homo- or heterodimerization, leading to autophosphorylation and recruitment of adapter proteins (such as GRB2). EGFR Protein, Mouse (HEK293, His) is the recombinant mouse-derived EGFR protein, expressed by HEK293 , with C-10*His labeled tag.

HY-P72987

	EGFR Protein, Human (Active, sf9, His-GST) 2 Publications Verification Epidermal growth factor receptor; EGFR; ErbB; ErbB1; HER1	Human	Sf9 insect cells
	EGFR is a transmembrane glycoprotein. EGFR binds to ligands, triggering receptor dimerization, inducing intracellular TK domain autophosphorylation, activating downstream Ras/MAPK, PI3K/Akt and other signaling pathways, and regulating cell proliferation, survival, migration and angiogenesis. EGFR Protein, Human (sf9, His-GST) is a recombinant EGFR protein expressed by Sf9 insect cells with N-His, N-GST tags.

HY-P705251

	EGFR Protein, Mouse (Biotinylated, HEK293, Fc-Avi) Epidermal growth factor receptor; EGFR; ErbB; ErbB1; HER1	Mouse	HEK293

HY-P705252

	EGFR Protein, Mouse (Biotinylated, HEK293, His-Avi) Epidermal growth factor receptor; EGFR; ErbB; ErbB1; HER1	Mouse	HEK293

HY-P73517

	EGFR Protein, Human (Biotinylated, 621a.a, HEK293, His) Epidermal growth factor receptor; EGFR; ErbB; ErbB1; HER1	Human	HEK293
	The EGFR protein is a receptor tyrosine kinase that can bind to a variety of ligands, such as EGF, TGFA, AREG, epigen, BTC, epiregulin, and HBEGF, to initiate signaling cascades that mediate cellular responses. This involves receptor dimerization, autophosphorylation and recruitment of adapter proteins such as GRB2, activating downstream pathways such as RAS-RAF-MEK-ERK, PI3-kinase-AKT, PLCgamma-PKC and STAT. EGFR Protein, Human (Biotinylated, 621a.a, HEK293, His) is the recombinant human-derived EGFR protein, expressed by HEK293 , with C-His labeled tag.

HY-P74177

	EGFR Protein, Human (621a.a, HEK293, Fc) 1 Publications Verification Epidermal growth factor receptor; EGFR; ErbB; ErbB1; HER1	Human	HEK293
	The EGFR protein is a receptor tyrosine kinase that can bind to a variety of ligands, such as EGF, TGFA, AREG, epigen, BTC, epiregulin, and HBEGF, to initiate signaling cascades that mediate cellular responses. This involves receptor dimerization, autophosphorylation and recruitment of adapter proteins such as GRB2, activating downstream pathways such as RAS-RAF-MEK-ERK, PI3-kinase-AKT, PLCgamma-PKC and STAT. EGFR Protein, Human (621a.a, HEK293, Fc) is the recombinant human-derived EGFR protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P705016

	EGFR Protein, Human (Biotinylated, 621a.a, HEK293, Fc-Avi) Epidermal growth factor receptor; EGFR; ErbB; ErbB1; HER1	Human	HEK293

HY-P7340

	EGFR Protein, Human (621a.a, CHO, His) rHuEGFR, His; ErbB; ErbB1; HER1	Human	CHO
	EGFR is a transmembrane glycoprotein. EGFR binds to ligands, triggering receptor dimerization, inducing intracellular TK domain autophosphorylation, activating downstream Ras/MAPK, PI3K/Akt and other signaling pathways, and regulating cell proliferation, survival, migration and angiogenesis. EGFR Protein, Human (621a.a, CHO, His) is a recombinant EGFR protein expressed by CHO, with a C-His tag and glycosylation modification.

HY-P70841

	HER4 Protein, Human (HEK293, His) Receptor tyrosine-protein kinase ErbB-4; Proto-oncogene-like protein c-ErbB-4; Tyrosine kinase-type cell surface receptor HER4; p180ErbB4; ErbB4; HER4	Human	HEK293
	HER4 is an important tyrosine protein kinase receptor for members of the neuregulin and EGF families that directs heart, central nervous system, and mammary gland development. It is critical for myocardial differentiation, postnatal cardiomyocyte proliferation, neural crest cell migration, axon guidance, and mammary gland function. HER4 Protein, Human (HEK293, His) is the recombinant human-derived HER4 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P7316

	EGFR Protein, Human (621a.a, sf9, His) rHuEGFR, His; ErbB1; HER1; ErbB	Human	Sf9 insect cells
	EGFR Protein, Human (sf9, His) is a glycosylated polypeptide chain with the C-termimal 6×His Tag produced in sf9 insect cells. EGFR, belongs to a family of tyrosine kinase receptors, plays important roles in cell growth and differentiation.

HY-P75259

	EGFR Protein, Cynomolgus (sf9, His) Epidermal growth factor receptor; EGFR; ErbB; ErbB1; HER1	Cynomolgus	Sf9 insect cells
	EGFR Protein is a receptor tyrosine kinase that binds to ligands of the EGF family. EGFR Protein is involved in the regulation of NF-kappa-B , RAS-RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs signaling pathways. EGFR Protein has calmodulin binding activity, epidermal growth factor binding activity and epidermal growth factor activating receptor activity. EGFR Protein, Cynomolgus (sf9, His) is the recombinant cynomolgus-derived EGFR protein, expressed by Sf9 insect cells , with C-His labeled tag.

HY-P75260

	EGFR Protein, Cynomolgus (HEK293, His) Epidermal growth factor receptor; EGFR; ErbB; ErbB1; HER1	Cynomolgus	HEK293
	EGFR Protein is a receptor tyrosine kinase that binds to ligands of the EGF family. EGFR Protein is involved in the regulation of NF-kappa-B , RAS-RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs signaling pathways. EGFR Protein has calmodulin binding activity, epidermal growth factor binding activity and epidermal growth factor activating receptor activity. EGFR Protein, Cynomolgus (HEK293, His) is the recombinant human-derived EGFR protein, expressed by HEK293 , with C-10*His labeled tag.

HY-P72625

	HER3 Protein, Human (HEK293, His) Receptor tyrosine-protein kinase ErbB-3; ErbB3; HER3	Human	HEK293
	HER3, a pivotal tyrosine-protein kinase, acts as a crucial cell receptor for neuregulins. Neuregulin-1 (NRG1) activation boosts tyrosine phosphorylation and interaction with p85 subunit of phosphatidylinositol 3-kinase. CSPG5 may also activate HER3. Its involvement in myeloid cell differentiation underscores HER3's vital role in essential cellular processes for normal development and function. HER3 Protein, Human (HEK293, His) is the recombinant human-derived HER3 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P74891

	HER3 Protein, Rat (HEK293, His) Receptor tyrosine-protein kinase ErbB-3; ErbB3; HER3	Rat	HEK293
	HER3, a pivotal tyrosine-protein kinase, acts as a crucial cell receptor for neuregulins. Neuregulin-1 (NRG1) activation boosts tyrosine phosphorylation and interaction with p85 subunit of phosphatidylinositol 3-kinase. CSPG5 may also activate HER3. Its involvement in myeloid cell differentiation underscores HER3's vital role in essential cellular processes for normal development and function. HER3 Protein, Rat (HEK293, His) is the recombinant rat-derived HER3 protein, expressed by HEK293 , with C-His labeled tag.

HY-P75257

	EGFR Protein, Rhesus Macaque (HEK293, His) Epidermal growth factor receptor; EGFR; ErbB; ErbB1; HER1	Rhesus Macaque	HEK293
	The EGFR protein is a receptor tyrosine kinase that can bind to a variety of ligands, such as EGF, TGFA, AREG, epigen, BTC, epiregulin, and HBEGF, to initiate signaling cascades that mediate cellular responses. This involves receptor dimerization, autophosphorylation and recruitment of adapter proteins such as GRB2, activating downstream pathways such as RAS-RAF-MEK-ERK, PI3-kinase-AKT, PLCgamma-PKC and STAT. EGFR Protein, Rhesus Macaque (HEK293, His) is the recombinant Rhesus Macaque-derived EGFR protein, expressed by HEK293 , with C-10*His labeled tag.

HY-P74892

	HER3 Protein, Rat (HEK293, Fc) Receptor tyrosine-protein kinase ErbB-3; ErbB3; HER3	Rat	HEK293
	HER3 is a tyrosine-protein kinase that is a key cell surface receptor for neuregulin. ErbB2 and ErbB3 can form dimers and activate signaling pathways including MAPK, PI3K/Akt and PLC纬 to promote tumor development. HER3 Protein, Rat (HEK293, Fc) is the recombinant rat-derived HER3 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P75256

	EGFR Protein, Rhesus Macaque (sf9, His) Epidermal growth factor receptor; EGFR; ErbB; ErbB1; HER1	Rhesus Macaque	Sf9 insect cells
	The EGFR protein is a receptor tyrosine kinase that can bind to a variety of ligands, such as EGF, TGFA, AREG, epigen, BTC, epiregulin, and HBEGF, to initiate signaling cascades that mediate cellular responses. This involves receptor dimerization, autophosphorylation and recruitment of adapter proteins such as GRB2, activating downstream pathways such as RAS-RAF-MEK-ERK, PI3-kinase-AKT, PLCgamma-PKC and STAT. EGFR Protein, Rhesus Macaque (sf9, His) is the recombinant Rhesus Macaque-derived EGFR protein, expressed by Sf9 insect cells , with C-His labeled tag.

HY-P75258

	EGFR Protein, Rhesus Macaque (HEK293, Fc) Epidermal growth factor receptor; EGFR; ErbB; ErbB1; HER1	Rhesus Macaque	HEK293
	The EGFR protein is a receptor tyrosine kinase that can bind to a variety of ligands, such as EGF, TGFA, AREG, epigen, BTC, epiregulin, and HBEGF, to initiate signaling cascades that mediate cellular responses. This involves receptor dimerization, autophosphorylation and recruitment of adapter proteins such as GRB2, activating downstream pathways such as RAS-RAF-MEK-ERK, PI3-kinase-AKT, PLCgamma-PKC and STAT. EGFR Protein, Rhesus Macaque (HEK293, Fc) is the recombinant Rhesus Macaque-derived EGFR protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P76967

	HER3 Protein, Rhesus Macaque (HEK293) Receptor tyrosine-protein kinase ErbB-3; ErbB3; HER3	Rhesus Macaque	HEK293
	HER3, a pivotal tyrosine-protein kinase, acts as a crucial cell receptor for neuregulins. Neuregulin-1 (NRG1) activation boosts tyrosine phosphorylation and interaction with p85 subunit of phosphatidylinositol 3-kinase. CSPG5 may also activate HER3. Its involvement in myeloid cell differentiation underscores HER3's vital role in essential cellular processes for normal development and function. HER3 Protein, Rhesus Macaque (HEK293) is the recombinant Rhesus Macaque-derived HER3 protein, expressed by HEK293 , with tag free.

HY-P701281

	FITC-labeled HER3 Protein, Human (HEK293, His-Avi) ErbB3; HER3; LCCS2; MDA-BF-1; MGC88033; c-ErbB3; ErbB3-S; p180-ErbB3; p45-sErbB3; p85-sErbB3	Human	HEK293
	HER3, a pivotal tyrosine-protein kinase, acts as a crucial cell receptor for neuregulins. Neuregulin-1 (NRG1) activation boosts tyrosine phosphorylation and interaction with p85 subunit of phosphatidylinositol 3-kinase. CSPG5 may also activate HER3. Its involvement in myeloid cell differentiation underscores HER3's vital role in essential cellular processes for normal development and function. FITC-labeled HER3 Protein, Human (HEK293, His) is the recombinant human-derived FITC-labeled HER3 protein, expressed by HEK293 , with C-His, C-Avi labeled tag.

HY-P76968

	HER3 Protein, Rhesus Macaque (HEK293, Fc) Receptor tyrosine-protein kinase ErbB-3; ErbB3; HER3	Rhesus Macaque	HEK293
	HER3, a pivotal tyrosine-protein kinase, acts as a crucial cell receptor for neuregulins. Neuregulin-1 (NRG1) activation boosts tyrosine phosphorylation and interaction with p85 subunit of phosphatidylinositol 3-kinase. CSPG5 may also activate HER3. Its involvement in myeloid cell differentiation underscores HER3's vital role in essential cellular processes for normal development and function. HER3 Protein, Rhesus Macaque (HEK293, Fc) is the recombinant Rhesus Macaque-derived HER3 protein, expressed by HEK293 , with C-hFc labeled tag.

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Cat. No.	Product Name	Chemical Structure

HY-50898S4

Lapatinib-d7
Lapatinib-d₇ (GW572016-d₇) is deuterium labeled Lapatinib. Lapatinib (GW572016) is a potent, orally active inhibitor of the *ErbB-2* and EGFR tyrosine kinase domains with IC₅₀ values against purified EGFR and *ErbB-2* of 10.2 and 9.8 nM, respectively .

HY-50898S1

Lapatinib-d7 dihydrochloride
Lapatinib-d₇ dihydrochloride is the deuterium labeled Lapatinib dihydrochloride. Lapatinib (GW572016) dihydrochloride is a potent, orally active inhibitor of the ErbB-2 and EGFR tyrosine kinase domains with IC₅₀ values against purified EGFR and ErbB-2 of 10.2 and 9.8 nM, respectively .

HY-50898S

Lapatinib-d4
Lapatinib-d₄ is the deuterium labeled Lapatinib (HY-50898). Lapatinib is a potent, orally active inhibitor of the ErbB-2 and EGFR tyrosine kinase domains with IC₅₀ values against purified EGFR and ErbB-2 of 10.2 and 9.8 nM, respectively .

HY-W062109S

Olopatadine-d6

Olopatadine-d₆ is the deuterium labeled Olopatadine. Olopatadine hydrochloride (ALO4943A; KW4679) is an orally active histamine H1 receptor antagonist and mast cell stabilizer. Olopatadine hydrochloride exerts antiallergic effects by blocking histamine H1 receptor-mediated activities. Olopatadine hydrochloride inhibits exocytosis, chemokine release, F-actin polymerization, CXCL10-induced calcium influx, and T cell chemotactic activity. Olopatadine hydrochloride also reduces the expression levels of CXCR3 on the surface of CD4 ⁺ and CD8 ⁺ T cells. Olopatadine hydrochloride inhibits scratching behavior, improves dermatitis scores, and suppresses intraepidermal neurite outgrowth. Olopatadine hydrochloride simultaneously decreases the levels of inflammatory markers, growth factors, histamine, and specific IgE, while increasing the expression of ErbB3A/HER3A. Olopatadine hydrochloride can be used in research related to seasonal pollinosis, chronic rhinitis, urticaria, allergic conjunctivitis, alopecia areata, and atopic dermatitis .

HY-B0426AS

Olopatadine-d3 hydrochloride

Olopatadine-d₃ hydrochloride (ALO4943A-d₃) is the deuterium labeled Olopatadine hydrochloride. Olopatadine hydrochloride (ALO4943A; KW4679) is an orally active histamine H1 receptor antagonist and mast cell stabilizer. Olopatadine hydrochloride exerts antiallergic effects by blocking histamine H1 receptor-mediated activities. Olopatadine hydrochloride inhibits exocytosis, chemokine release, F-actin polymerization, CXCL10-induced calcium influx, and T cell chemotactic activity. Olopatadine hydrochloride also reduces the expression levels of CXCR3 on the surface of CD4 ⁺ and CD8 ⁺ T cells. Olopatadine hydrochloride inhibits scratching behavior, improves dermatitis scores, and suppresses intraepidermal neurite outgrowth. Olopatadine hydrochloride simultaneously decreases the levels of inflammatory markers, growth factors, histamine, and specific IgE, while increasing the expression of ErbB3A/HER3A. Olopatadine hydrochloride can be used in research related to seasonal pollinosis, chronic rhinitis, urticaria, allergic conjunctivitis, alopecia areata, and atopic dermatitis .

HY-50898S2

Lapatinib-d5
Lapatinib-d₅ is deuterium labeled Lapatinib. Lapatinib (GW572016) is a potent, orally active inhibitor of the ErbB-2 and EGFR tyrosine kinase domains with IC₅₀ values against purified EGFR and ErbB-2 of 10.2 and 9.8 nM, respectively .

HY-50898S3

Lapatinib-d4-1
Lapatinib-d₄-1 is deuterium labeled Lapatinib. Lapatinib (GW572016) is a potent, orally active inhibitor of the ErbB-2 and EGFR tyrosine kinase domains with IC₅₀ values against purified EGFR and ErbB-2 of 10.2 and 9.8 nM, respectively .

HY-50898CS

Lapatinib-d4 tosylate
Lapatinib-d₄ (GW572016-d₄) tosylate is deuterium labeled Lapatinib (tosylate). Lapatinib (GW572016) tosylate is a potent, orally active inhibitor of the *ErbB-2* and EGFR tyrosine kinase domains with IC₅₀ values against purified EGFR and *ErbB-2* of 10.2 and 9.8 nM, respectively .

HY-W777297

Lapatinib-13C2,15N Ditosylate
Lapatinib- ¹³C₂, ¹⁵N Ditosylate is the ¹³C- and ¹⁵N-labeled Lapatinib ditosylate (HY-50898A). Lapatinib ditosylate (GW572016 ditosylate) is a potent inhibitor of the ErbB-2 and EGFR tyrosine kinase domains with IC₅₀ values against purified EGFR and ErbB-2 of 10.2 and 9.8 nM, respectively .

HY-13272S3

Dacomitinib-d10
Dacomitinib-d₁₀ is deuterium labeled Dacomitinib. Dacomitinib (PF-00299804) is a specific and irreversible inhibitor of the ERBB family of kinases with IC₅₀s of 6 nM, 45.7 nM and 73.7 nM for EGFR, ERBB2, and ERBB4, respectively .

HY-13272S2

Dacomitinib-d10 dihydrochloride
Dacomitinib-d₁₀ dihydrochloride is the deuterium labeled Dacomitinib dihydrochloride. Dacomitinib (PF-00299804) dihydrochloride is a specific and irreversible inhibitor of the ERBB family of kinases with IC₅₀s of 6 nM, 45.7 nM and 73.7 nM for EGFR, ERBB2, and ERBB4, respectively .

HY-32718S

Pelitinib-d6
Pelitinib-d₆ (EKB-569-d₆) is the deuterium labeled Pelitinib. Pelitinib (EKB-569) is an irreversible inhibitor of EGFR with an IC₅₀ of 38.5 nM; also slightly inhibits Src, MEK/ERK and ErbB2 with IC₅₀s of 282, 800, and 1255 nM, respectively .

HY-B0793S1

AZ-5104-d2
AZ-5104-d₂ is the deuterium labeled AZ-5104. AZ-5104 is an EGFR inhibitor with IC₅₀s of 1 nM, 6 nM, 1 nM, 25 nM and 7 nM for EGFRL858R/T790M, EGFRL858R, EGFRL861Q, EGFR and ErbB4, respectively .

HY-B0426AS2

Olopatadine-d6 hydrochloride

Olopatadine-d₆ (ALO4943A-d₆; KW4679-d₆) hydrochloride is deuterium-labeled Olopatadine (hydrochloride) (HY-B0426A). Olopatadine hydrochloride (ALO4943A; KW4679) is an orally active histamine H1 receptor antagonist and mast cell stabilizer. Olopatadine hydrochloride exerts antiallergic effects by blocking histamine H1 receptor-mediated activities. Olopatadine hydrochloride inhibits exocytosis, chemokine release, F-actin polymerization, CXCL10-induced calcium influx, and T cell chemotactic activity. Olopatadine hydrochloride also reduces the expression levels of CXCR3 on the surface of CD4 ⁺ and CD8 ⁺ T cells. Olopatadine hydrochloride inhibits scratching behavior, improves dermatitis scores, and suppresses intraepidermal neurite outgrowth. Olopatadine hydrochloride simultaneously decreases the levels of inflammatory markers, growth factors, histamine, and specific IgE, while increasing the expression of ErbB3A/HER3A. Olopatadine hydrochloride can be used in research related to seasonal pollinosis, chronic rhinitis, urticaria, allergic conjunctivitis, alopecia areata, and atopic dermatitis .

Host:	Mouse (17) Rabbit (32)
Reactivity:	Human (48) Rat (15) Mouse (18) Monkey (3)
Application:	IHC-P (30) ICC/IF (29) mIHC (2) IF-Tissue (6) IP (18) IHC-F (10) WB (48) FC (12) ELISA (14)
Isotype:	IgG, Kappa (1) IgG (32) IgG1 (13) IgG, Kappa (1) IgG2a (1)
Conjugation:	Non-conjugated (49) Biotin (21)
Clonality:	Polyclonal (1) Monoclonal (22) Monoclonal Antibody (2) Recombinant (11)
Modification:	Phosphorylated (6) Unmodified (19)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P86375

	EGFR Antibody (YA6067) EGFR; ErbB; ErbB1; HER1; Epidermal growth factor receptor; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase ErbB-1	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat
	EGFR Antibody (YA6067) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to EGFR.

HY-P85843

	EGFR Antibody (YA5535) EGFR; ErbB; ErbB1; HER1; Epidermal growth factor receptor; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase ErbB-1	IHC-P, WB, ICC/IF, ELISA	Human
	EGFR Antibody (YA5535) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to EGFR.

HY-P83891

	EGFR mutant (L858R) Antibody (YA3588) ErbB; HER1; mENA; ErbB1; PIG61; L858R mutant	WB, IHC-P, FC, ELISA	Human
	EGFR mutant (L858R) Antibody (YA3588) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to EGFR mutant.

HY-P83891A

	EGFR mutant (L858R) Antibody (YA3588)(PBS only) ErbB; HER1; mENA; ErbB1; PIG61; L858R mutant	WB, IHC-P, FC, ELISA	Human
	EGFR mutant (L858R) Antibody (YA3588) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to EGFR mutant.

HY-P86718

	EGFR Antibody (YA6410) EGFR; Avian erythroblastic leukemia viral(v erb b) oncogene homolog; Avian erythroblastic leukemia viral(vErbB) oncogene homolog; Cell growth inhibiting protein 40; Cell proliferation inducing protein 61; EGF R; EGFR; Epidermal growth factor receptor(avian erythroblastic leukemia viral(v erb b) oncogene homolog); Epidermal growth factor receptor(erythroblastic leukemia viral(v erb b) oncogene homolog avian); Epidermal growth factor receptor; ErbB 1; ErbB; ErbB1; HER1; mENA; Oncogene ErbB; PIG61; Receptor tyrosine protein kinase ErbB 1; Receptor tyrosine protein kinase ErbB1; Urogastrone; wa2; Wa5; EGFR_HUMAN.	WB, IHC-P, IHC-F, IF-Tissue	Human
	EGFR Antibody (YA6410) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to EGFR.

HY-P85600

	EGFR Antibody (YA5292) Avian erythroblastic leukemia viral; v erb b; oncogene homolog; Cell growth inhibiting protein 40; Cell proliferation inducing protein 61; EGF R; EGFR; EGFR_HUMAN; Epidermal growth factor receptor; avian erythroblastic leukemia viral; v erb b; oncogene homolog; Epidermal growth factor receptor; erythroblastic leukemia viral; v erb b; oncogene homolog avian; Epidermal growth factor receptor; ErbB 1; ErbB; ErbB1; ErbB1; Errp; HER1; mENA; Oncogene ErbB; PIG61; Proto-oncogene c-ErbB-1; Receptor tyrosine protein kinase ErbB 1; Receptor tyrosine-protein kinase ErbB-1; Urogastrone; wa2; Wa5.	WB, IHC-P, ICC/IF, IP	Human, Monkey
	EGFR Antibody (YA5292) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to EGFR.

HY-P86718A

	EGFR Antibody (YA6410)(PBS only) EGFR; Avian erythroblastic leukemia viral(v erb b) oncogene homolog; Avian erythroblastic leukemia viral(vErbB) oncogene homolog; Cell growth inhibiting protein 40; Cell proliferation inducing protein 61; EGF R; EGFR; Epidermal growth factor receptor(avian erythroblastic leukemia viral(v erb b) oncogene homolog); Epidermal growth factor receptor(erythroblastic leukemia viral(v erb b) oncogene homolog avian); Epidermal growth factor receptor; ErbB 1; ErbB; ErbB1; HER1; mENA; Oncogene ErbB; PIG61; Receptor tyrosine protein kinase ErbB 1; Receptor tyrosine protein kinase ErbB1; Urogastrone; wa2; Wa5; EGFR_HUMAN.	WB, IHC-P, IHC-F, IF-Tissue	Human
	EGFR Antibody (YA6410) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to EGFR.

HY-P80648

	EGFR Antibody (YA775) EGFR; ErbB; ErbB1; HER1; Epidermal growth factor receptor; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase ErbB-1	WB, ICC/IF, IP	Human, Monkey
	EGFR Antibody (YA775) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to EGFR.

HY-P810668

	Phospho-EGFR (Tyr1148) Antibody EGFR; ErbB; ErbB1; HER1; Epidermal growth factor receptor; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase ErbB-1	WB, ICC/IF	Human
	Phospho-EGFR (Tyr1148) Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to Phospho-EGFR (Tyr1148).

HY-P80648A

	EGFR Antibody (YA775)(PBS only) EGFR; ErbB; ErbB1; HER1; Epidermal growth factor receptor; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase ErbB-1	WB, ICC/IF, IP	Human, Monkey
	EGFR Antibody (YA775) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to EGFR.

HY-P80808

	Phospho-EGFR (Tyr1068) Antibody (YA207) EGFR; ErbB; ErbB1; HER1; Epidermal growth factor receptor; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase ErbB-1	WB, IHC-F, IHC-P, ICC/IF	Human
	Phospho-EGFR (Tyr1068) Antibody (YA207) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-EGFR (Tyr1068).

HY-P80809

	Phospho-EGFR (Tyr1092) Antibody (YA206) EGFR; ErbB; ErbB1; HER1; Epidermal growth factor receptor; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase ErbB-1	WB, IHC-P	Human, Mouse, Rat
	Phospho-EGFR (Tyr1092) Antibody (YA206) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-EGFR (Tyr1092).

HY-P80810

	Phospho-EGFR (Tyr1173) Antibody (YA205) EGFR; ErbB; ErbB1; HER1; Epidermal growth factor receptor; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase ErbB-1	WB, IHC-F, IHC-P, ICC/IF, IP	Human
	Phospho-EGFR (Tyr1173) Antibody (YA205) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-EGFR (Tyr1173).

HY-P810669

	Phospho-EGFR (Tyr1092) Antibody (YA9928) EGFR; ErbB; ErbB1; HER1; Epidermal growth factor receptor; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase ErbB-1	WB, IF-Tissue, IHC-P	Human, Mouse
	Phospho-EGFR (Tyr1092) Antibody (YA9928) is a Rabbit-derived and non-conjugated IgG Recombinant, Monoclonal antibody, targeting to Phospho-EGFR (Tyr1092).

HY-P810670

	Phospho-EGFR (Tyr1045) Antibody (YA9929) EGFR; ErbB; ErbB1; HER1; Epidermal growth factor receptor; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase ErbB-1	WB, ICC/IF, FC	Human
	Phospho-EGFR (Tyr1045) Antibody (YA9929) is a Rabbit-derived and non-conjugated IgG Recombinant, Monoclonal antibody, targeting to Phospho-EGFR (Tyr1045).

HY-P810671

	Phospho-EGFR (Tyr845) Antibody (YA9930) EGFR; ErbB; ErbB1; HER1; Epidermal growth factor receptor; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase ErbB-1	WB	Human
	Phospho-EGFR (Tyr845) Antibody (YA9930) is a Rabbit-derived and non-conjugated IgG Recombinant, Monoclonal antibody, targeting to Phospho-EGFR (Tyr845).

HY-P810672

	Phospho-EGFR (Thr669) Antibody (YA9931) EGFR; ErbB; ErbB1; HER1; Epidermal growth factor receptor; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase ErbB-1	WB, IP	Human, Mouse, Rat
	Phospho-EGFR (Thr669) Antibody (YA9931) is a Rabbit-derived and non-conjugated IgG Recombinant, Monoclonal antibody, targeting to Phospho-EGFR (Thr669).

HY-P810673

	Phospho-EGFR (Ser695) Antibody (YA9932) EGFR; ErbB; ErbB1; HER1; Epidermal growth factor receptor; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase ErbB-1	WB, ICC/IF, IF-Tissue	Human
	Phospho-EGFR (Ser695) Antibody (YA9932) is a Rabbit-derived and non-conjugated IgG Recombinant, Monoclonal antibody, targeting to Phospho-EGFR (Ser695).

HY-P810674

	Phospho-EGFR (Tyr1173) Antibody (YA9933) EGFR; ErbB; ErbB1; HER1; Epidermal growth factor receptor; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase ErbB-1	WB, ICC/IF, IHC-P, IP	Human, Mouse
	Phospho-EGFR (Tyr1173) Antibody (YA9933) is a Rabbit-derived and non-conjugated IgG Recombinant, Monoclonal antibody, targeting to Phospho-EGFR (Tyr1173).

HY-P80660

	*C-erbB-4/HER4 Antibody (YA456)* ErbB4; HER4; Receptor tyrosine-protein kinase ErbB-4; Proto-oncogene-like protein c-ErbB-4; Tyrosine kinase-type cell surface receptor HER4; p180ErbB4	WB	Human, Rat
	C-erbB-4/HER4 Antibody (YA456) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to C-erbB-4/HER4.

HY-P80808A

	Phospho-EGFR (Tyr1068) Antibody (YA207)(PBS only) EGFR; ErbB; ErbB1; HER1; Epidermal growth factor receptor; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase ErbB-1	WB, IHC-F, IHC-P, ICC/IF	Human
	Phospho-EGFR (Tyr1068) Antibody (YA207) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-EGFR (Tyr1068).

HY-P80809A

	Phospho-EGFR (Tyr1092) Antibody (YA206)(PBS only) EGFR; ErbB; ErbB1; HER1; Epidermal growth factor receptor; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase ErbB-1	WB, IHC-P	Human, Mouse, Rat
	Phospho-EGFR (Tyr1092) Antibody (YA206) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-EGFR (Tyr1092).

HY-P80810A

	Phospho-EGFR (Tyr1173) Antibody (YA205)(PBS only) EGFR; ErbB; ErbB1; HER1; Epidermal growth factor receptor; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase ErbB-1	WB, IHC-F, IHC-P, ICC/IF, IP	Human
	Phospho-EGFR (Tyr1173) Antibody (YA205) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-EGFR (Tyr1173).

HY-P84183

	*C-erbB-3/HER3 Antibody (YA3880)* HER3; c-ErbB3	WB, ICC/IF, ELISA	Human
	C-erbB-3/HER3 Antibody (YA3880) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to C-erbB-3/HER3.

HY-P80660A

	*C-erbB-4/HER4 Antibody (YA456)(PBS only)* ErbB4; HER4; Receptor tyrosine-protein kinase ErbB-4; Proto-oncogene-like protein c-ErbB-4; Tyrosine kinase-type cell surface receptor HER4; p180ErbB4	WB	Human, Rat
	C-erbB-4/HER4 Antibody (YA456) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to C-erbB-4/HER4.

HY-P87595

	ErbB4 Antibody (YA7279)	FC, ICC/IF, IP
	ErbB4 Antibody (YA7279) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to ErbB4.

HY-P87728

	ErbB-4 Antibody (YA7413)	WB, ICC/IF, IP, ELISA	Human, Mouse, Rat
	ErbB-4 Antibody (YA7413) is a Rabbit-derived and non-conjugated IgG, Kappa monoclonal antibody, targeting to ErbB-4.

HY-P80659

	*C-erbB-3/HER3 Antibody (YA457)* ErbB3; HER3; Receptor tyrosine-protein kinase ErbB-3; Proto-oncogene-like protein c-ErbB-3; Tyrosine kinase-type cell surface receptor HER3	WB, IHC-P, FC	Human, Mouse
	C-erbB-3/HER3 Antibody (YA457) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to C-erbB-3/HER3.

HY-P86321

	*C-erbB-3/HER3 Antibody (YA6013)* ErbB3; HER3; Receptor tyrosine-protein kinase ErbB-3; Proto-oncogene-like protein c-ErbB-3; Tyrosine kinase-type cell surface receptor HER3	WB, ICC/IF, IP, ELISA	Human, Mouse, Rat
	C-erbB-3/HER3 Antibody (YA6013) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to C-erbB-3/HER3.

HY-P84183A

	*C-erbB-3/HER3 Antibody (YA3880)(PBS only)* HER3; c-ErbB3	WB, ICC/IF, ELISA	Human
	C-erbB-3/HER3 Antibody (YA3880) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to C-erbB-3/HER3.

HY-P80659A

	*C-erbB-3/HER3 Antibody (YA457)(PBS only)* ErbB3; HER3; Receptor tyrosine-protein kinase ErbB-3; Proto-oncogene-like protein c-ErbB-3; Tyrosine kinase-type cell surface receptor HER3	WB, IHC-P, FC	Human, Mouse
	C-erbB-3/HER3 Antibody (YA457) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to C-erbB-3/HER3.

HY-P810612

	*Phospho-HER3/ErbB3 (Tyr1222) Antibody (YA9874)* ErbB3; HER3; Receptor tyrosine-protein kinase ErbB-3; Proto-oncogene-like protein c-ErbB-3; Tyrosine kinase-type cell surface receptor HER3	WB, IHC-P	Human
	Phospho-HER3/ErbB3 (Tyr1222) Antibody (YA9874) is a Rabbit-derived and non-conjugated IgG Recombinant, Monoclonal antibody, targeting to Phospho-HER3/ErbB3 (Tyr1222).

HY-P810613

	*Phospho-ErbB3/HER3 (Tyr1289) Antibody (YA9875)* ErbB3; HER3; Receptor tyrosine-protein kinase ErbB-3; Proto-oncogene-like protein c-ErbB-3; Tyrosine kinase-type cell surface receptor HER3	WB, ICC/IF	Human
	Phospho-ErbB3/HER3 (Tyr1289) Antibody (YA9875) is a Rabbit-derived and non-conjugated IgG Recombinant, Monoclonal antibody, targeting to Phospho-ErbB3/HER3 (Tyr1289).

HY-P80658

	*C-erbB-2/HER2 Antibody (YA771)* ErbB2; HER2; MLN19; NEU; NGL; Receptor tyrosine-protein kinase ErbB-2; Metastatic lymph node gene 19 protein; MLN 19; Proto-oncogene Neu; Proto-oncogene c-ErbB-2; Tyrosine kinase-type cell surface receptor HER2; p185ErbB2; CD antigen CD340	WB, IHC-F, IHC-P, ICC/IF	Human, Mouse, Rat
	C-erbB-2/HER2 Antibody (YA771) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to C-erbB-2/HER2.

HY-P80500

	*C-erbB-2/HER2 Antibody (YA388)*	WB, IHC-P, ICC/IF, FC, mIHC	Human
	C-erbB-2/HER2 Antibody (YA388) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to C-erbB-2/HER2.

HY-P87912

	*Phospho-ErbB-3 (Tyr1289) Antibody (YA7597)*	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat
	Phospho-ErbB-3 (Tyr1289) Antibody (YA7597) is a Rabbit-derived and non-conjugated IgG, Kappa monoclonal antibody, targeting to Phospho-ErbB-3 (Tyr1289).

HY-P83761

	*Phospho-C-erbB-2/HER2(Tyr1221/Tyr1222) Antibody* ErbB2; HER2; MLN19; NEU; NGL; Receptor tyrosine-protein kinase ErbB-2; Metastatic lymph node gene 19 protein; MLN 19; Proto-oncogene Neu; Proto-oncogene c-ErbB-2; Tyrosine kinase-type cell surface receptor HER2; p185ErbB2; CD antigen CD340	WB, IHC-P, IP, ELISA	Human, Mouse
	Phospho-C-erbB-2/HER2(Tyr1221/Tyr1222) Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to Phospho-C-erbB-2/HER2(Tyr1221/Tyr1222).

HY-P80658A

	*C-erbB-2/HER2 Antibody (YA771)(PBS only)* ErbB2; HER2; MLN19; NEU; NGL; Receptor tyrosine-protein kinase ErbB-2; Metastatic lymph node gene 19 protein; MLN 19; Proto-oncogene Neu; Proto-oncogene c-ErbB-2; Tyrosine kinase-type cell surface receptor HER2; p185ErbB2; CD antigen CD340	WB, IHC-F, IHC-P, ICC/IF	Human, Mouse, Rat
	C-erbB-2/HER2 Antibody (YA771) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to C-erbB-2/HER2.

HY-P810658

	*Phospho-HER2 / ErbB2 (Thr686) Antibody (YA9918)* ErbB2; HER2; MLN19; NEU; NGL; Receptor tyrosine-protein kinase ErbB-2; Metastatic lymph node gene 19 protein; MLN 19; Proto-oncogene Neu; Proto-oncogene c-ErbB-2; Tyrosine kinase-type cell surface receptor HER2; p185ErbB2; CD antigen CD340	WB, IP	Human, Mouse, Rat
	Phospho-HER2 / ErbB2 (Thr686) Antibody (YA9918) is a Mouse-derived and non-conjugated IgG1 Monoclonal antibody, targeting to Phospho-HER2 / ErbB2 (Thr686).

HY-P810659

	*Phospho-HER2 / ErbB2 (Tyr1139) Antibody (YA9919)* ErbB2; HER2; MLN19; NEU; NGL; Receptor tyrosine-protein kinase ErbB-2; Metastatic lymph node gene 19 protein; MLN 19; Proto-oncogene Neu; Proto-oncogene c-ErbB-2; Tyrosine kinase-type cell surface receptor HER2; p185ErbB2; CD antigen CD340	WB, ICC/IF, FC	Human
	Phospho-HER2 / ErbB2 (Tyr1139) Antibody (YA9919) is a Rabbit-derived and non-conjugated IgG Recombinant, Monoclonal antibody, targeting to Phospho-HER2 / ErbB2 (Tyr1139).

HY-P810657

	*Phospho-HER2 / ErbB2 (Tyr1248) Antibody (YA9917)* ErbB2; HER2; MLN19; NEU; NGL; Receptor tyrosine-protein kinase ErbB-2; Metastatic lymph node gene 19 protein; MLN 19; Proto-oncogene Neu; Proto-oncogene c-ErbB-2; Tyrosine kinase-type cell surface receptor HER2; p185ErbB2; CD antigen CD340	WB, ICC/IF	Human
	Phospho-HER2 / ErbB2 (Tyr1248) Antibody (YA9917) is a Rabbit-derived and non-conjugated IgG Recombinant, Monoclonal antibody, targeting to Phospho-HER2 / ErbB2 (Tyr1248).

HY-P86242

	*C-erbB-2/HER2 Antibody (YA5934)* Receptor tyrosine-protein kinase ErbB-2; Metastatic lymph node gene 19 protein; MLN 19; Proto-oncogene Neu; Proto-oncogene c-ErbB-2; Tyrosine kinase-type cell surface receptor HER2; p185ErbB2; CD antigen CD340;	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat
	C-erbB-2/HER2 Antibody (YA5934) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to C-erbB-2/HER2.

HY-P86166

	*Phospho-C-erbB-2/HER2(Tyr1221/Tyr1222) Antibody (YA5858)* Receptor tyrosine-protein kinase ErbB-2; Metastatic lymph node gene 19 protein; MLN 19; Proto-oncogene Neu; Proto-oncogene c-ErbB-2; Tyrosine kinase-type cell surface receptor HER2; p185ErbB2; CD antigen CD340;	WB, ICC/IF, IP, ELISA	Human
	Phospho-C-erbB-2/HER2(Tyr1221/Tyr1222) Antibody (YA5858) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-C-erbB-2/HER2(Tyr1221/Tyr1222).

HY-P80116

	EGFR Antibody (YA468) 1 Publications Verification Avian erythroblastic leukemia viral (v erb b) oncogene homolog antibody; Cell growth inhibiting protein 40 antibody; Cell proliferation inducing protein 61 antibody; EGF R antibody; EGFR antibody; EGFR_HUMAN antibody; Epidermal growth factor receptor (avian erythroblastic leukemia viral (v erb b) oncogene homolog) antibody; Epidermal growth factor receptor antibody; erb-b2 receptor tyrosine kinase 1 antibody; ErbB antibody; ErbB1 antibody; Errp antibody; HER1 antibody; mENA antibody; NISBD2 antibody; Oncogen ErbB antibody; PIG61 antibody; Proto-oncogene c-ErbB-1 antibody; Receptor tyrosine protein kinase ErbB 1 antibody; Receptor tyrosine-protein kinase ErbB-1 antibody; SA7 antibody; Species antigen 7 antibody; Urogastrone antibody; v-erb-b Avian erythroblastic leukemia viral oncogen homolog antibody; wa2 antibody; Wa5 antibody	WB, IHC-P, ICC/IF, IP, FC, mIHC	Human, Mouse, Rat
	EGFR Antibody (YA468) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to EGFR.

HY-P83946

	*C-erbB-2/HER2 Antibody (YA3643)* NEU; HER2; TKR1; CD340; HER-2	WB, IHC-P, FC, ELISA	Human
	C-erbB-2/HER2 Antibody (YA3643) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to C-erbB-2/HER2.

HY-P83946A

	*C-erbB-2/HER2 Antibody (YA3643)(PBS only)* NEU; HER2; TKR1; CD340; HER-2	WB, IHC-P, FC, ELISA	Human
	C-erbB-2/HER2 Antibody (YA3643) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to C-erbB-2/HER2.

HY-P86719

	*C-erbB-2/HER2 Antibody (YA6411)* Erb-B2 Receptor Tyrosine Kinase 2; NGL; NEU; V-Erb-B2 Avian Erythroblastic Leukemia Viral Oncogene Homolog 2; Tyrosine Kinase-Type Cell Surface Receptor HER2; Neuro/Glioblastoma Derived Oncogene Homolog; Human Epidermal Growth Factor Receptor 2; Metastatic Lymph Node Gene 19 Protein; Proto-Oncogene C-ErbB-2; Proto-Oncogene Neu; EC 2.7.10.1; P185ErbB2; MLN 19; V-Erb-B2 Avian Erythroblastic Leukemia Viral Oncogene Homolog 2; V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/Glioblastoma Derived Oncogene Homolog; V-Erb-B2 Avian Erythroblastic Leukemia Viral Oncoprotein 2; Neuroblastoma/Glioblastoma Derived Oncogene Homolog; Receptor Tyrosine-Protein Kinase ErbB-2; C-Erb B2/Neu Protein; CD340 Antigen; Herstatin; EC 2.7.10; CD340; HER-2; MLN19; TKR1;	WB, IHC-P, IHC-F, IF-Tissue	Human
	C-erbB-2/HER2 Antibody (YA6411) is a Mouse-derived and non-conjugated IgG monoclonal antibody, targeting to C-erbB-2/HER2.

HY-P86719A

	*C-erbB-2/HER2 Antibody (YA6411)(PBS only)* Erb-B2 Receptor Tyrosine Kinase 2; NGL; NEU; V-Erb-B2 Avian Erythroblastic Leukemia Viral Oncogene Homolog 2; Tyrosine Kinase-Type Cell Surface Receptor HER2; Neuro/Glioblastoma Derived Oncogene Homolog; Human Epidermal Growth Factor Receptor 2; Metastatic Lymph Node Gene 19 Protein; Proto-Oncogene C-ErbB-2; Proto-Oncogene Neu; EC 2.7.10.1; P185ErbB2; MLN 19; V-Erb-B2 Avian Erythroblastic Leukemia Viral Oncogene Homolog 2; V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/Glioblastoma Derived Oncogene Homolog; V-Erb-B2 Avian Erythroblastic Leukemia Viral Oncoprotein 2; Neuroblastoma/Glioblastoma Derived Oncogene Homolog; Receptor Tyrosine-Protein Kinase ErbB-2; C-Erb B2/Neu Protein; CD340 Antigen; Herstatin; EC 2.7.10; CD340; HER-2; MLN19; TKR1;	WB, IHC-P, IHC-F, IF-Tissue	Human
	C-erbB-2/HER2 Antibody (YA6411) is a Mouse-derived and non-conjugated IgG monoclonal antibody, targeting to C-erbB-2/HER2.

HY-P82764

	EBP1 Antibody (YA2509) PA2G4; EBP1; Proliferation-associated protein 2G4; Cell cycle protein p38-2G4 homolog; hG4-1; ErbB3-binding protein 1	WB, IHC-P, ICC/IF, FC, IP	Human, Mouse, Rat
	EBP1 Antibody (YA2509) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to EBP1.

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Cat. No.	Product Name		Classification

HY-RS04209

EGFR Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
EGFR Human Pre-designed siRNA Set A contains three designed siRNAs for EGFR gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS04472

ERBB4 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
ERBB4 Human Pre-designed siRNA Set A contains three designed siRNAs for ERBB4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS04466

ERBB2 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
ERBB2 Human Pre-designed siRNA Set A contains three designed siRNAs for ERBB2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-160068

2-2(t) aptamer sodium		Aptamers
2-2(t) aptamer sodium is a 42-nucleotide trimeric complex of aptamer (2-2) targeting *ErbB-2*. 2-2(t) aptamer sodium inhibits the growth of gastric cancer cells in vitro and in vivo .

HY-RS04474

Erbb4 Rat Pre-designed siRNA Set A		siRNAs Rat Pre-designed siRNA Sets
Erbb4 Rat Pre-designed siRNA Set A contains three designed siRNAs for Erbb4 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS04468

ERBB2 Rat Pre-designed siRNA Set A		siRNAs Rat Pre-designed siRNA Sets
ERBB2 Rat Pre-designed siRNA Set A contains three designed siRNAs for ERBB2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS04469

ERBB3 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
ERBB3 Human Pre-designed siRNA Set A contains three designed siRNAs for ERBB3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS04473

Erbb4 Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Erbb4 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Erbb4 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS04471

Erbb3 Rat Pre-designed siRNA Set A		siRNAs Rat Pre-designed siRNA Sets
Erbb3 Rat Pre-designed siRNA Set A contains three designed siRNAs for Erbb3 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS04467

Erbb2 Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Erbb2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Erbb2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS04470

Erbb3 Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Erbb3 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Erbb3 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-174671

Human HBEGF mRNA		mRNA
Human HBEGF mRNA encodes the human heparin binding EGF like growth factor (HBEGF) protein, a growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. HBEGF may be involved in normal cardiac valve formation and normal heart function.

HY-174565

Human NRG3 mRNA		mRNA
Human NRG3 mRNA encodes the human neuregulin 3 (NRG3) protein, a member of the neuregulin gene family. NRG3 has been shown to activate the tyrosine phosphorylation of its cognate receptor, ERBB4, and is thought to influence neuroblast proliferation, migration and differentiation by signalling through ERBB4. NRG3 also promotes mammary differentiation during embryogenesis.

HY-RS04210

Egfr Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Egfr Mouse Pre-designed siRNA Set A contains three designed siRNAs for Egfr gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-174566

Human NRG2 mRNA		mRNA
Human NRG2 mRNA encodes the human neuregulin 2 (NRG2) protein, a novel member of the neuregulin family of growth and differentiation factors. Through interaction with the ERBB family of receptors, NRG2 can induce the growth and differentiation of epithelial, neuronal, glial, and other types of cells.

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