1050500-29-2
Chemical Structure
Allitinib tosylate
Synonym(s): AST-1306 (TsOH)
- CAS No.: 1050500-29-2
- Formula:C31H26ClFN4O5S
- Molecular Weight:621.08
IUPAC Name: N-(4-((3-chloro-4-((3-fluorobenzyl)oxy)phenyl)amino)quinazolin-6-yl)acrylamide 4-methylbenzenesulfonate
InChIKey: ZMUKJEHWLJBODV-UHFFFAOYSA-N
SMILES: FC1=CC=CC(COC2=C(Cl)C=C(NC3=NC=NC4=C3C=C(NC(C=C)=O)C=C4)C=C2)=C1.O=S(C5=CC=C(C)C=C5)(O)=O
Biological Activity: Allitinib tosylate (AST-1306 (TsOH)) is an orally active and irreversible EGFR and ErbB2 inhibitor with IC50s of 0.5 and 3 nM, respectively. Allitinib tosylate also inhibits ErbB4 with an IC50 of 0.8 nM. Allitinib tosylate is an anilino-quinazoline compound and has anti-cancer activity[1]
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Allitinib tosylate | 99.54% | Allitinib tosylate (AST-1306 (TsOH)) is an orally active and irreversible EGFR and ErbB2 inhibitor with IC50s of 0.5 and 3 nM, respectively. Allitinib tosylate also inhibits ErbB4 with an IC50 of 0.8 nM. Allitinib tosylate is an anilino-quinazoline compound and has anti-cancer activity | ||||||||||||||||||||
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