848942-61-0
848942-61-0
Chemical Structure
Sapitinib
Synonym(s): AZD-8931
- CAS No.: 848942-61-0
- Formula:C23H25ClFN5O3
- Molecular Weight:473.93
IUPAC Name: 2-(4-((4-((3-chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)oxy)piperidin-1-yl)-N-methylacetamide
InChIKey: DFJSJLGUIXFDJP-UHFFFAOYSA-N
SMILES: O=C(CN1CCC(OC2=CC3=C(NC4=CC=CC(Cl)=C4F)N=CN=C3C=C2OC)CC1)NC
Biological Activity: Sapitinib (AZD-8931) is a reversible, ATP competitive EGFR inhibitor of with IC50s of 4, 3 and 4 nM for EGFR, ErbB2 and ErbB3 in cells, respectively.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Sapitinib | 99.93% | Sapitinib (AZD-8931) is a reversible, ATP competitive EGFR inhibitor of with IC50s of 4, 3 and 4 nM for EGFR, ErbB2 and ErbB3 in cells, respectively. | ||||||||||||||||||||
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Keywords
