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European corn borer

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By Targets:	Caspase (1) Insecticide (3) NOD-like Receptor (NLR) (1) Pyroptosis (1) Ser/Thr Protease (1)
By Research Areas:	Infection (2)

Inhibitors & Agonists

Natural
Products

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-117901

Sandoricin	Insecticide	Others
Sandoricin is a limonoid compound that can be extracted from the seeds of Sandoricum koetjape. Sandoricin exhibits strong antifeedant properties in larvae of Fall Armyworm (Spodoptera frugiperda) and European Corn Borer (Ostrinia nubilalis) fed on artificial diets. Sandoricin induces reduced growth rate and delayed pupation at lower doses, while higher doses cause massive mortality of larvae. Sandoricin is a potential field insecticide .

HY-W720758

3,7,11-Trimethyl-1-dodecanol	Insecticide	Infection
3,7,11-Trimethyl-1-dodecanol is an alcohol volatile organic compound present in Spirulina platensis, with a faint odor. 3,7,11-Trimethyl-1-dodecanol inhibits the oviposition behavior of female Ostrinia nubilalis (European corn borer). 3,7,11-Trimethyl-1-dodecanol can be used in studies related to behavioral regulation of agricultural pests .

HY-178898

7-Oxogedunin	NOD-like Receptor (NLR) Caspase Insecticide Ser/Thr Protease Pyroptosis	Infection
7-Oxogedunin (Compound 7DG; Compound 16) is a small molecule that protects macrophages from cell pyroptosis induced by anthrax lethal toxin (LT). Its target is protein kinase R (PKR). 7-Oxogedunin can widely inhibit the assembly of various inflammasomes (NLRP1 and NLRP3) and the activation of caspase-1 by inhibiting the kinase-independent function of PKR. 7-Oxogedunin has growth inhibitory activity on European corn borer larvae. 7-Oxogedunin can be used for LT toxicity inhibition and pest control research .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-117901

Sandoricin	Natural Products Sandoricum koetjape (Burm. f.) Merr. Plants Meliaceae Source Classification	Insecticide
Sandoricin is a limonoid compound that can be extracted from the seeds of Sandoricum koetjape. Sandoricin exhibits strong antifeedant properties in larvae of Fall Armyworm (Spodoptera frugiperda) and European Corn Borer (Ostrinia nubilalis) fed on artificial diets. Sandoricin induces reduced growth rate and delayed pupation at lower doses, while higher doses cause massive mortality of larvae. Sandoricin is a potential field insecticide .

HY-W720758

3,7,11-Trimethyl-1-dodecanol	Structural Classification Natural Products Manihot esculenta Crantz Euphorbiaceae Plants Source Classification	Insecticide
3,7,11-Trimethyl-1-dodecanol is an alcohol volatile organic compound present in Spirulina platensis, with a faint odor. 3,7,11-Trimethyl-1-dodecanol inhibits the oviposition behavior of female Ostrinia nubilalis (European corn borer). 3,7,11-Trimethyl-1-dodecanol can be used in studies related to behavioral regulation of agricultural pests .

HY-178898

7-Oxogedunin	Structural Classification Natural Products Swietenia humilis Zucc. Plants Meliaceae Source Classification	NOD-like Receptor (NLR) Caspase Insecticide Ser/Thr Protease Pyroptosis
7-Oxogedunin (Compound 7DG; Compound 16) is a small molecule that protects macrophages from cell pyroptosis induced by anthrax lethal toxin (LT). Its target is protein kinase R (PKR). 7-Oxogedunin can widely inhibit the assembly of various inflammasomes (NLRP1 and NLRP3) and the activation of caspase-1 by inhibiting the kinase-independent function of PKR. 7-Oxogedunin has growth inhibitory activity on European corn borer larvae. 7-Oxogedunin can be used for LT toxicity inhibition and pest control research .

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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European corn borer

Inhibitors & Agonists

NaturalProducts

Natural
Products