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FAK-IN-4

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-124625
    BI-4464

    		FAK Target Protein Ligand-Linker Conjugates Infection Cancer
    BI-4464 is a highly selective, ATP competitive PTK2/FAK protein kinase inhibitor with an IC50 value of 17 nM. BI-4464 is a FAK (HY-43760) ligand and linker conjugate. BI-4464 can be used to construct proteolysis targeting chimeras (PROTACs), such as PROTAC FAK degrader 4 (HY-178467). PROTAC FAK degrader 4 is a highly potent and selective FAK PROTAC degrader .
    BI-4464
  • HY-146065
    FAK-IN-4

    		FAK Apoptosis Cancer
    FAK-IN-4 (Compound 7d) is potential FAK inhibitor with anticancer activities. FAK-IN-4 induces cell apoptosis .
    FAK-IN-4
  • HY-178467
    PROTAC FAK degrader 4

    		FAK PROTACs Cancer
    PROTAC FAK degrader 4 (Compound 9C) is an efficient and selective FAK PROTAC degrader. PROTAC FAK degrader 4 has a DC50 of 3.6 nM in MDA-MB-231 cells. PROTAC FAK degrader 4 significantly inhibits tumor cell proliferation, migration, and invasion, and enhances chemotherapy sensitivity to cisplatin (HY-17394). PROTAC FAK degrader 4 can be used for research on cancer. (Pink: FAK Ligand (HY-43760); Blue: VHL Ligand (HY-125845); Black: Linker (HY-W208616))
    PROTAC FAK degrader 4
  • HY-43760
    FAK ligand-5

    		Ligands for Target Protein for PROTAC FAK Cancer
    FAK ligand-5 is a FAK ligand. FAK ligand-5 can be coupled with a linker to synthesize BI-4464 (HY-124625). FAK ligand-5 can be used as a target protein ligand for PROTAC development, specifically for designing PROTAC FAK degraders. FAK ligand-5 can be used in the synthesis of PROTAC FAK degrader 4 (HY-178467). FAK ligand-5 can be used in cancer research .
    FAK ligand-5
  • HY-W208616
    trans-4-Aminocyclohexylacetic acid

    		PROTAC Linkers Cancer
    trans-4-Aminocyclohexylacetic acid is a PROTAC linker that can be used in the synthesis of PROTACs, such as PROTAC FAK degrader 4 (HY-178467) .
    trans-4-Aminocyclohexylacetic acid
  • HY-178483
    E3 Ligase Ligand-linker Conjugate 211

    		E3 Ligase Ligand-Linker Conjugates Cancer
    E3 Ligase Ligand-linker Conjugate 211 is an E3 ligase ligand-linker conjugate containing a cereblon (CRBN) ligand for E3 ubiquitin ligase and a linker. E3 Ligase Ligand-linker Conjugate 211 can be used to synthesize PROTAC FAK degrader 4 (HY-178467) .
    E3 Ligase Ligand-linker Conjugate 211

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