PROTAC FAK degrader 4
PROTAC FAK degrader 4 (Compound 9C) is an efficient and selective FAK PROTAC degrader. PROTAC FAK degrader 4 has a DC50 of 3.6 nM in MDA-MB-231 cells. PROTAC FAK degrader 4 significantly inhibits tumor cell proliferation, migration, and invasion, and enhances chemotherapy sensitivity to cisplatin (HY-17394). PROTAC FAK degrader 4 can be used for research on cancer. (Pink: FAK Ligand (HY-43760); Blue: VHL Ligand (HY-125845); Black: Linker (HY-W208616))
(Pink: FAK ligand (HY-43760); Blue: VHL ligand (HY-125845); Black: linker (HY-W208616)).
For research use only. We do not sell to patients.
- Formula: C52H57F3N8O8S
- Molecular Weight:1011.12
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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- References
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Biological Activity
Chemical Information
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Molecular Weight 1011.12
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Formula C52H57F3N8O8S
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SMILES
O=C([C@H]1N(C([C@@H](NC(C[C@H]2CC[C@H](NC(C3=CC=C(NC4=NC=C(C(F)(F)F)C(OC5=CC=CC(CC6)=C5C6=O)=N4)C(OC)=C3)=O)CC2)=O)C(C)(C)C)=O)C[C@H](O)C1)NCC7=CC=C(C8=C(C)N=CS8)C=C7
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PROTAC FAK degrader 4 Related Classifications
HY-178467 Related Classifications
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