FAK ligand-5
FAK ligand-5 is a FAK ligand. FAK ligand-5 can be coupled with a linker to synthesize BI-4464 (HY-124625). FAK ligand-5 can be used as a target protein ligand for PROTAC development, specifically for designing PROTAC FAK degraders. FAK ligand-5 can be used in the synthesis of PROTAC FAK degrader 4 (HY-178467). FAK ligand-5 can be used in cancer research.
For research use only. We do not sell to patients.
- CAS No.: 1227948-58-4
- Formula: C22H16F3N3O5
- Molecular Weight:459.37
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
IC50: 25 nM (FAK)
Chemical Information
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CAS No. 1227948-58-4
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Molecular Weight 459.37
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Formula C22H16F3N3O5
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SMILES
O=C(O)C1=CC=C(NC2=NC=C(C(F)(F)F)C(OC3=CC=CC(CC4)=C3C4=O)=N2)C(OC)=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)