Search Result
Results for "
Fluorochrome
" in MedChemExpress (MCE) Product Catalog:
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-D1627
-
|
CM-DiI
|
Fluorescent Dye
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Others
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CellTracker CM-DiI (CM-DiI) is a lipophilic fluorochrome that can be used for tracking the migration of lymphocytes. CellTracker CM-DiI is feasible to detect labeled cells in histological sections (excitation 553 nm; emission 570 nm) .
|
-
-
- HY-P0028
-
|
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Fluorescent Dye
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Others
|
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Phalloidin is a mushroom-derived toxin which can be used to label F-actin of the cytoskeleton with fluorochrome
.
|
-
-
- HY-D0093
-
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EthD-1
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DNA Stain
|
Others
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Ethidium homodimer (EthD-1) is a high-affinity fluorescent nucleic acid dye commonly used to stain mammals, bacteria, yeast, and fungi. Ethidium homodimer binds to DNA or RNA, enhancing fluorescence more than 30 times. The Ethidium homodimer has a strong positive charge, so it cannot cross cell membranes and stain living cells; But the Ethidium homodimer can cross the disordered region of the dead cell membrane to reach the nucleus and embed the DNA double strand to produce red fluorescence. Therefore, Ethidium homodimer is a relatively sensitive nucleic acid stain that can accurately detect nucleic acids in solution or in decomposing cells. Ethidium homodimer binds DNA, Ex/Em=528/617 nm .
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-
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- HY-D0917
-
|
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DNA Stain
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Cancer
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NIR-Red Dead Cell-1 Dye is a DNA-binding fluorescent dye for non-living cells (Ex/Em=515 nm/531 nm). NIR-Red Dead Cell-1 Dye can intercalate into base pairs of double-stranded DNA and produce stronger fluorescence. NIR-Red Dead Cell-1 Dye is suitable for necrotic cells or late apoptotic cells with damaged cell membranes, showing green fluorescence under fluorescence microscopy or flow cytometry. NIR-Red Dead Cell-1 Dye can be used to distinguish live cells from dead cells and distinguish cell membrane integrity. NIR-Red Dead Cell-1 Dye can be attached to the surface of Feraheme (FH) nanoparticles (NPs) to obtain fluorescent dye-functionalized NPs for drug delivery studies .
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-
-
- HY-D0918
-
|
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Fluorescent Dye
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Others
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YO-PRO-1 is a non-cell-membrane-penetrating green fluorescent dye. YO-PRO-1 cannot penetrate normal cell membranes but can penetrate the membranes of apoptotic and necrotic cells. YO-PRO-1 has a high affinity for DNA. When it is not bound to DNA, it emits almost no fluorescence, and when it binds to DNA, it can emit green fluorescence (Ex/Em: 488/530±30 nM). YO-PRO-1 is often used together with Propidium Iodide (HY-D0815) to analyze and identify apoptotic and necrotic cells .
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-
-
- HY-130433
-
|
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Fluorescent Dye
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Others
|
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NBD Sphingosine (NBD-Sph), a fluorochrome, is a fluorescence-labeled sphingosine. NBD Sphingosine can be uesd for fluorescence assay for sphingosine kinases .
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- HY-136936
-
|
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Fluorescent Dye
|
Others
|
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PYBG-BODIPY is a dye and has a role as a fluorochrome. PYBG-BODIPY specifically and efficiently labels the target genetically encoded SNAP-tags in live cells .
|
-
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- HY-W127705
-
|
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Fluorescent Dye
|
Others
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Quinacrine mustard dihydrochloride is a fluorochrome. Quinacrine mustard dihydrochloride as a polycyclic aromatic agent can be used as mutagenic agent induces the mutants of bacteria. Quinacrine mustard dihydrochloride induces cell cycle arrest at G2/M-phase. Quinacrine mustard dihydrochloride has the potential for the research of plant, animal, or human chromosomes .
|
-
-
- HY-D1072
-
|
3,3′-Dipentyloxacarbocyanine iodide
|
Fluorescent Dye
|
Others
|
|
DiOC5(3) is the membrane potential (MP)-modifying fluorochrome. DiOC5(3) is an anti-LSC compound available for diagnostic imaging. DiOC5(3) has the advantage of being a single fluorescent chemical .
|
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-
- HY-D1560
-
|
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Fluorescent Dye
|
Others
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FG 488 DHPE is a lipid-coupled fluorochrome, has be used as a fluorophore Oregon Green 488. FG 488 DHPE monitors acidification of lipid vesicles with λex/λem=508/534 nm.FG 488 DHPE is also used for Hv1-induced proton translocation quantificatio with λex/λem=508/534 nm as well .
|
-
-
- HY-P2496
-
|
|
Endothelin Receptor
Fluorescent Dye
NF-κB
COX
Prostaglandin Receptor
Apoptosis
TNF Receptor
Interleukin Related
MMP
|
Cardiovascular Disease
Inflammation/Immunology
Cancer
|
|
Endothelin 1 (swine, human), Alexa Fluor 488-labeled is an Endothelin-1 conjugated with Alexa Fluor 488 (HY-D1304). Endothelin-1 is an endogenous vasoconstrictor and agonist of ETA/ETB receptor. Endothelin 1 (swine, human) exerts effects including promoting mitosis, angiogenesis, tumor invasion and metastasis, and inhibiting apoptosis. Endothelin 1 (swine, human) induces inflammation and oxidative stress by activating the NF-κB pathway. Endothelin 1 (swine, human), Alexa Fluor 488-labeled is specifically designed for fluorescence imaging, flow cytometry or receptor localization studies, and can be used in research related to sepsis, atherosclerosis, systemic inflammatory response syndrome, cancer and congestive heart failure .
|
-
-
- HY-P5372A
-
|
|
Protease Activated Receptor (PAR)
|
Cancer
|
|
Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2 TFA, a bioactive peptide, is a selective Protease activating receptor 1 (PAR-1) agonist over PAR-2. PAR-1 belongs to a subfamily of G-protein coupled receptors and is known to mediate the cellular effects of thrombin. In addition to its varied cellular effects of thrombin, PAR-1 has also been shown to coordinate with PAR-4 and regulate thrombin-induced hepatocellular carcinoma harboring thrombin formation within the tumor environment classified as 'coagulation type' .
|
-
-
- HY-D1589
-
-
-
- HY-136937
-
|
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Fluorescent Dye
|
Others
|
|
PYBG-TMR is a dye and has a role as a fluorochrome. PYBG-TMR specifically and efficiently labels the target genetically encoded SNAP-tags in live cells . PYBG-TMR is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
-
- HY-D2766
-
|
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Fluorescent Dye
|
Others
|
|
BP Light 550 NHS ester is a vibrant orange-to-red fluorochrome with better performance than other rhodamine derivatives, including BP Fluor 555, TRITC, and Cy3 dye for fluorescent applications. The high water solubility of BP Light 550 means that a high dye-to-protein ratio can be attained without causing precipitation of the conjugates.
|
-
-
- HY-P5372
-
|
|
Protease Activated Receptor (PAR)
|
Cancer
|
|
Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2, a bioactive peptide, is a selective Protease activating receptor 1 (PAR-1) agonist over PAR-2. PAR-1 belongs to a subfamily of G-protein coupled receptors and is known to mediate the cellular effects of thrombin. In addition to its varied cellular effects of thrombin, PAR-1 has also been shown to coordinate with PAR-4 and regulate thrombin-induced hepatocellular carcinoma harboring thrombin formation within the tumor environment classified as 'coagulation type' .
|
-
-
- HY-159841A
-
|
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Fluorescent Dye
|
Others
|
|
Filricianine sodium is an hydrophilic fluorochrome. It can be conjugated to antibody with higher D/P ratio and widely used applications including western blotting, microscopy, flow cytometry, and cell based assays.
|
-
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- HY-D2736
-
|
|
Fluorescent Dye
|
Others
|
|
BP Light 800 NHS ester is an amine reactive hydrophilic fluorochrome . It can be conjugated to antibody with higher D/P ratio and widely used applications including western blotting, microscopy, flow cytometry, and cell based assays.
|
-
-
- HY-D1525
-
|
|
Fluorescent Dye
|
Others
|
|
N-(7-Nitrobenzofurazan-4-yl)phallacidin is a fluorochrome. N-(7-Nitrobenzofurazan-4-yl)phallacidin can be used visualizing probe for actin .
|
-
-
- HY-D2754
-
|
|
Fluorescent Dye
|
Others
|
|
BP Light 550 acid is a vibrant orange-to-red fluorochrome with better performance t han other rhodamine derivatives, including BP Fluor 555, TRITC, and Cy3 dye for fluorescent applications. The high water solubility of BP Light Fluors means that a high dye-to-protein ratio can be attained without causing precipitation of the conjugates.
|
-
-
- HY-D2761
-
|
|
Fluorescent Dye
|
Others
|
|
DY-680-NHS ester is an amine reactive hydrophilic fluorochrome. It can be conjugated to an antibody with higher D/P ratio without causing fluorescence quenching and conjugate precipitation, and it is widely used in applications including western blotting, microscopy, flow cytometry, and cell-based assays. The spectrum has an excitation of 690nm and emission at 709nm.
|
-
-
- HY-D3330
-
|
|
Fluorescent Dye
|
Others
|
|
APC-Cy7 is an APC-tandem fluorochrome (allophycocyanin-cyanine 7) and degradable fluorochrome, with maximum absorption at ~650 nm, peak emission at 767 nm when excited by a 633 nm red laser, and cell-dependent degradation. APC-Cy7 undergoes time-dependent degradation (decoupling) when bound to peripheral blood leukocytes, leading to nonspecific APC channel signal, with degradation cell type-dependent. APC-Cy7 shows reduced degradation when immunolabeled cells have inhibited metabolic activity or are incubated with vitamin C. APC-Cy7 serves as a tandem fluorochrome in multiparametric flow cytometry for detection of leukocyte surface proteins when conjugated to specific antibodies (Ex/Em = 650 nm/778 nm) .
|
-
-
- HY-D3320
-
|
|
Fluorescent Dye
|
Others
|
|
APC-AF700 is a tandem fluorochrome conjugate for flow cytometry. APC-AF700 can be incorporated into 10-color and 12-color flow cytometry antibody panels (Ex/Em = 633/715 nm) .
|
-
-
- HY-D2755
-
|
|
Fluorescent Dye
|
Others
|
|
BP Light 650 carboxylic acid is an vibrant far-red fluorochrome with comparable or improved performance over other dyes, including BP Fluor 647 and Cy5 dye, for fluorescent applications. It is used to label antibodies and other proteins as molecular probes for cellular imaging and other fluorescence detection methods application.
|
-
| Cat. No. |
Product Name |
Type |
-
- HY-D1627
-
|
CM-DiI
|
Fluorescent Dyes
|
|
CellTracker CM-DiI (CM-DiI) is a lipophilic fluorochrome that can be used for tracking the migration of lymphocytes. CellTracker CM-DiI is feasible to detect labeled cells in histological sections (excitation 553 nm; emission 570 nm) .
|
-
- HY-D0093
-
|
EthD-1
|
Fluorescent Dyes
|
|
Ethidium homodimer (EthD-1) is a high-affinity fluorescent nucleic acid dye commonly used to stain mammals, bacteria, yeast, and fungi. Ethidium homodimer binds to DNA or RNA, enhancing fluorescence more than 30 times. The Ethidium homodimer has a strong positive charge, so it cannot cross cell membranes and stain living cells; But the Ethidium homodimer can cross the disordered region of the dead cell membrane to reach the nucleus and embed the DNA double strand to produce red fluorescence. Therefore, Ethidium homodimer is a relatively sensitive nucleic acid stain that can accurately detect nucleic acids in solution or in decomposing cells. Ethidium homodimer binds DNA, Ex/Em=528/617 nm .
|
-
- HY-D0917
-
|
|
Fluorescent Dyes
|
|
NIR-Red Dead Cell-1 Dye is a DNA-binding fluorescent dye for non-living cells (Ex/Em=515 nm/531 nm). NIR-Red Dead Cell-1 Dye can intercalate into base pairs of double-stranded DNA and produce stronger fluorescence. NIR-Red Dead Cell-1 Dye is suitable for necrotic cells or late apoptotic cells with damaged cell membranes, showing green fluorescence under fluorescence microscopy or flow cytometry. NIR-Red Dead Cell-1 Dye can be used to distinguish live cells from dead cells and distinguish cell membrane integrity. NIR-Red Dead Cell-1 Dye can be attached to the surface of Feraheme (FH) nanoparticles (NPs) to obtain fluorescent dye-functionalized NPs for drug delivery studies .
|
-
- HY-D0918
-
|
|
Fluorescent Dyes
|
|
YO-PRO-1 is a non-cell-membrane-penetrating green fluorescent dye. YO-PRO-1 cannot penetrate normal cell membranes but can penetrate the membranes of apoptotic and necrotic cells. YO-PRO-1 has a high affinity for DNA. When it is not bound to DNA, it emits almost no fluorescence, and when it binds to DNA, it can emit green fluorescence (Ex/Em: 488/530±30 nM). YO-PRO-1 is often used together with Propidium Iodide (HY-D0815) to analyze and identify apoptotic and necrotic cells .
|
-
- HY-130433
-
|
|
Fluorescent Dyes
|
|
NBD Sphingosine (NBD-Sph), a fluorochrome, is a fluorescence-labeled sphingosine. NBD Sphingosine can be uesd for fluorescence assay for sphingosine kinases .
|
-
- HY-136936
-
|
|
Fluorescent Dyes
|
|
PYBG-BODIPY is a dye and has a role as a fluorochrome. PYBG-BODIPY specifically and efficiently labels the target genetically encoded SNAP-tags in live cells .
|
-
- HY-W127705
-
|
|
Fluorescent Dyes
|
|
Quinacrine mustard dihydrochloride is a fluorochrome. Quinacrine mustard dihydrochloride as a polycyclic aromatic agent can be used as mutagenic agent induces the mutants of bacteria. Quinacrine mustard dihydrochloride induces cell cycle arrest at G2/M-phase. Quinacrine mustard dihydrochloride has the potential for the research of plant, animal, or human chromosomes .
|
-
- HY-D1072
-
|
3,3′-Dipentyloxacarbocyanine iodide
|
Fluorescent Dyes
|
|
DiOC5(3) is the membrane potential (MP)-modifying fluorochrome. DiOC5(3) is an anti-LSC compound available for diagnostic imaging. DiOC5(3) has the advantage of being a single fluorescent chemical .
|
-
- HY-D1560
-
|
|
Fluorescent Dyes
|
|
FG 488 DHPE is a lipid-coupled fluorochrome, has be used as a fluorophore Oregon Green 488. FG 488 DHPE monitors acidification of lipid vesicles with λex/λem=508/534 nm.FG 488 DHPE is also used for Hv1-induced proton translocation quantificatio with λex/λem=508/534 nm as well .
|
-
- HY-136937
-
|
|
Fluorescent Dyes
|
|
PYBG-TMR is a dye and has a role as a fluorochrome. PYBG-TMR specifically and efficiently labels the target genetically encoded SNAP-tags in live cells . PYBG-TMR is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-D2766
-
|
|
Fluorescent Dyes
|
|
BP Light 550 NHS ester is a vibrant orange-to-red fluorochrome with better performance than other rhodamine derivatives, including BP Fluor 555, TRITC, and Cy3 dye for fluorescent applications. The high water solubility of BP Light 550 means that a high dye-to-protein ratio can be attained without causing precipitation of the conjugates.
|
-
- HY-D2736
-
|
|
Fluorescent Dyes
|
|
BP Light 800 NHS ester is an amine reactive hydrophilic fluorochrome . It can be conjugated to antibody with higher D/P ratio and widely used applications including western blotting, microscopy, flow cytometry, and cell based assays.
|
-
- HY-D1525
-
|
|
Fluorescent Dyes
|
|
N-(7-Nitrobenzofurazan-4-yl)phallacidin is a fluorochrome. N-(7-Nitrobenzofurazan-4-yl)phallacidin can be used visualizing probe for actin .
|
-
- HY-D2754
-
|
|
Fluorescent Dyes
|
|
BP Light 550 acid is a vibrant orange-to-red fluorochrome with better performance t han other rhodamine derivatives, including BP Fluor 555, TRITC, and Cy3 dye for fluorescent applications. The high water solubility of BP Light Fluors means that a high dye-to-protein ratio can be attained without causing precipitation of the conjugates.
|
-
- HY-D2761
-
|
|
Fluorescent Dyes
|
|
DY-680-NHS ester is an amine reactive hydrophilic fluorochrome. It can be conjugated to an antibody with higher D/P ratio without causing fluorescence quenching and conjugate precipitation, and it is widely used in applications including western blotting, microscopy, flow cytometry, and cell-based assays. The spectrum has an excitation of 690nm and emission at 709nm.
|
-
- HY-D3330
-
|
|
Fluorescent Dyes
|
|
APC-Cy7 is an APC-tandem fluorochrome (allophycocyanin-cyanine 7) and degradable fluorochrome, with maximum absorption at ~650 nm, peak emission at 767 nm when excited by a 633 nm red laser, and cell-dependent degradation. APC-Cy7 undergoes time-dependent degradation (decoupling) when bound to peripheral blood leukocytes, leading to nonspecific APC channel signal, with degradation cell type-dependent. APC-Cy7 shows reduced degradation when immunolabeled cells have inhibited metabolic activity or are incubated with vitamin C. APC-Cy7 serves as a tandem fluorochrome in multiparametric flow cytometry for detection of leukocyte surface proteins when conjugated to specific antibodies (Ex/Em = 650 nm/778 nm) .
|
-
- HY-D3320
-
|
|
Fluorescent Dyes
|
|
APC-AF700 is a tandem fluorochrome conjugate for flow cytometry. APC-AF700 can be incorporated into 10-color and 12-color flow cytometry antibody panels (Ex/Em = 633/715 nm) .
|
-
- HY-D2755
-
|
|
Fluorescent Dyes
|
|
BP Light 650 carboxylic acid is an vibrant far-red fluorochrome with comparable or improved performance over other dyes, including BP Fluor 647 and Cy5 dye, for fluorescent applications. It is used to label antibodies and other proteins as molecular probes for cellular imaging and other fluorescence detection methods application.
|
| Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-P0028
-
|
|
Fluorescent Dye
|
Others
|
|
Phalloidin is a mushroom-derived toxin which can be used to label F-actin of the cytoskeleton with fluorochrome
.
|
-
- HY-P2496
-
|
|
Endothelin Receptor
Fluorescent Dye
NF-κB
COX
Prostaglandin Receptor
Apoptosis
TNF Receptor
Interleukin Related
MMP
|
Cardiovascular Disease
Inflammation/Immunology
Cancer
|
|
Endothelin 1 (swine, human), Alexa Fluor 488-labeled is an Endothelin-1 conjugated with Alexa Fluor 488 (HY-D1304). Endothelin-1 is an endogenous vasoconstrictor and agonist of ETA/ETB receptor. Endothelin 1 (swine, human) exerts effects including promoting mitosis, angiogenesis, tumor invasion and metastasis, and inhibiting apoptosis. Endothelin 1 (swine, human) induces inflammation and oxidative stress by activating the NF-κB pathway. Endothelin 1 (swine, human), Alexa Fluor 488-labeled is specifically designed for fluorescence imaging, flow cytometry or receptor localization studies, and can be used in research related to sepsis, atherosclerosis, systemic inflammatory response syndrome, cancer and congestive heart failure .
|
-
- HY-P5372A
-
|
|
Protease Activated Receptor (PAR)
|
Cancer
|
|
Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2 TFA, a bioactive peptide, is a selective Protease activating receptor 1 (PAR-1) agonist over PAR-2. PAR-1 belongs to a subfamily of G-protein coupled receptors and is known to mediate the cellular effects of thrombin. In addition to its varied cellular effects of thrombin, PAR-1 has also been shown to coordinate with PAR-4 and regulate thrombin-induced hepatocellular carcinoma harboring thrombin formation within the tumor environment classified as 'coagulation type' .
|
-
- HY-P5373
-
|
|
Peptides
|
Others
|
|
Ser-parafluoroPhe-Aad-Leu-Arg-Asn-Pro-NH2 is a biological active peptide. (Structure-activity studies of thrombin receptor-tethered ligand SFLLRNP have revealed
the importance of the Phe-2-phenyl group in receptor recognition and the replacement of the
Phe-2 by para-fluorophenylalanine [(p-F)Phe] was found to enhance its activity)
|
-
- HY-P5372
-
|
|
Protease Activated Receptor (PAR)
|
Cancer
|
|
Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2, a bioactive peptide, is a selective Protease activating receptor 1 (PAR-1) agonist over PAR-2. PAR-1 belongs to a subfamily of G-protein coupled receptors and is known to mediate the cellular effects of thrombin. In addition to its varied cellular effects of thrombin, PAR-1 has also been shown to coordinate with PAR-4 and regulate thrombin-induced hepatocellular carcinoma harboring thrombin formation within the tumor environment classified as 'coagulation type' .
|
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