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  3. Quinacrine mustard dihydrochloride

Quinacrine mustard dihydrochloride is a fluorochrome. Quinacrine mustard dihydrochloride as a polycyclic aromatic agent can be used as mutagenic agent induces the mutants of bacteria. Quinacrine mustard dihydrochloride induces cell cycle arrest at G2/M-phase. Quinacrine mustard dihydrochloride has the potential for the research of plant, animal, or human chromosomes.

For research use only. We do not sell to patients.

Quinacrine mustard dihydrochloride Chemical Structure

Quinacrine mustard dihydrochloride Chemical Structure

CAS No. : 4213-45-0

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Description

Quinacrine mustard dihydrochloride is a fluorochrome. Quinacrine mustard dihydrochloride as a polycyclic aromatic agent can be used as mutagenic agent induces the mutants of bacteria. Quinacrine mustard dihydrochloride induces cell cycle arrest at G2/M-phase. Quinacrine mustard dihydrochloride has the potential for the research of plant, animal, or human chromosomes[1][2][3].

In Vitro

Quinacrine mustard dihydrochloride (5 μg/ml) can be used for the DNA strain of plant, animal, or human chromosomes[1].
Quinacrine mustard dihydrochloride (28 μM) increases the number of mutants that appeared after an exposure of bacteria[2].
quinacrine mustard dihydrochloride (0.2 μM; 4h) induces cell cycle arrest at G2+M-phase in HL-60 cells[3].
Caffeine (5 mM) prevents the cytotoxic action of quinacrine mustard dihydrochloride (0.2 μM; 4h) in HL-60 cells[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Cycle Analysis[3]

Cell Line: HL-60 cells
Concentration: 0.2 µM
Incubation Time: 4 h
Result: Induced cell cycle arrest at G2+M-phase with the accumulation of cells in this compartment by 50%.
Molecular Weight

541.77

Formula

C23H30Cl5N3O

CAS No.
SMILES

CC(CCCN(CCCl)CCCl)N=C1C2=C(C=C(C=C2)Cl)NC3=C1C=C(C=C3)OC.Cl.Cl

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Quinacrine mustard dihydrochloride Related Classifications

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Product Name:
Quinacrine mustard dihydrochloride
Cat. No.:
HY-W127705
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