438476-80-3
Chemical Structure
FG 488 DHPE
- CAS No.: 438476-80-3
- Formula:C58H82F2NO14P
- Molecular Weight:1086.24
IUPAC Name: tetrakis(acetoxymethyl) 2,2',2'',2'''-(((ethane-1,2-diylbis(oxy))bis(4-(3',6'-diacetoxy-2',7'-difluoro-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthene]-5-carboxamido)-2,1-phenylene))bis(azanetriyl))tetraacetate
InChIKey: IXJDCQVYVRWFPD-VZUYHUTRSA-N
SMILES: O=C1OC2(C3=CC(F)=C(O)C=C3OC4=CC(O)=C(F)C=C42)C5=CC=C(C(NCCOP(OC[C@@H](COC(CCCCCCCCCCCCCCC)=O)OC(CCCCCCCCCCCCCCC)=O)(O)=O)=O)C=C51
Biological Activity: FG 488 DHPE is a lipid-coupled fluorochrome, has be used as a fluorophore Oregon Green 488. FG 488 DHPE monitors acidification of lipid vesicles with λex/λem=508/534 nm.FG 488 DHPE is also used for Hv1-induced proton translocation quantificatio with λex/λem=508/534 nm as well[1][2].
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FG 488 DHPE | FG 488 DHPE is a lipid-coupled fluorochrome, has be used as a fluorophore Oregon Green 488. FG 488 DHPE monitors acidification of lipid vesicles with λex/λem=508/534 nm.FG 488 DHPE is also used for Hv1-induced proton translocation quantificatio with λex/λem=508/534 nm as well. | |||||||||||||||||||||
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- [1]. Schwamborn M, et al. Monitoring ATPase induced pH changes in single proteoliposomes with the lipid-coupled fluorophore Oregon Green 488. Analyst. 2017 Jul 10;142(14):2670-2677. [Content Brief]
- [2]. Gerdes B, et al. Quantification of Hv1-induced proton translocation by a lipid-coupled Oregon Green 488-based assay. Anal Bioanal Chem. 2018 Oct;410(25):6497-6505. [Content Brief]
Keywords