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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
22 Results for "
G2A
" in MedChemExpress (MCE) Product Catalog:
Products (22)
22 Results for "G2A" in MCE Product Catalog:
5
5 Cited Publications
Cat. No.: HY-P990679
Target:
Research Areas:
3
3 Cited Publications
Cat. No.: HY-P74628
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Phospholipase A2, membrane associated; EF; GIIC sPLA2
Species:
Source:
Synonyms: 18:1 Lyso-PS
Research Areas:
Oleoyl-2-hydroxy-sn-glycero-3-phospho-L-serine sodium (18:1 Lyso-PS) is a modified PS product generated following NADPH oxidase activation and Lyso-PS signal transduction. 1-Oleoyl-2-hydroxy-sn-glycero-3-phospho-L-serine sodium signals through macrophage G2A to enhance the phagocytic uptake of PS-dependent apoptotic (apoptosis) neutrophils and PS-exposed activated neutrophils. 1-Oleoyl-2-hydroxy-sn-glycero-3-phospho-L-serine sodium enhances macrophage phagocytic uptake of apoptotic cells, carboxylate-modified microspheres, and PS-exposed non-apoptotic activated neutrophils. 1-Oleoyl-2-hydroxy-sn-glycero-3-phospho-L-serine sodium serves as an acyl acceptor substrate for the lysophosphatidyltransferase At1g78690p to generate diacylphosphatidylserine. 1-Oleoyl-2-hydroxy-sn-glycero-3-phospho-L-serine sodium reduces the secretion of IL-8 and decreases the proportion of viable colon cancer cells. 1-Oleoyl-2-hydroxy-sn-glycero-3-phospho-L-serine sodium is applicable to studies on peritonitis and inflammatory bowel disease [2] .
Cat. No.: HY-163763
CAS No.: 1608784-68-4
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T-10418 is a potent and highly selective G2A/GPR132 agonist. T-10418 has an EC50 of 0.82 μM for human G2A activation. T-10418 has good water solubility, metabolic stability, and pharmacokinetic properties. T-10418 can be used for the research of various diseases such as neuropathic pain, acute myeloid leukemia, and inflammation .
Cat. No.: HY-P990845
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Research Areas:
Cat. No.: HY-P10389
Cat. No.: HY-NP0196B
Cat. No.: HY-171854
CAS No.: 3040121-49-8
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Research Areas:
SB-583355 (Compound 56) is a potent G2A antagonist. SB-583355 can be prepared by a Suzuki reaction between 4-methoxyphenyl boronic acid and 3-bromo-4-hydroxybenzoic acid following the conditions followed by an amide coupling reaction. SB-583355 blocks the activation of G2A mediated either by 9-HOPE or T-10148 in human G2A expressing CHO-K1 cells. SB-583355 can be studied in research for inflammation, myeloid leukemia, and neuropathic pain .
Cat. No.: HY-119494
CAS No.: 193825-78-4
Category:
Microorganisms Ketones, Aldehydes, Acids Endogenous metabolite Disease Research Fields Inflammation/Immunology
Target:
Cat. No.: HY-RS10621
Target:
Research Areas:
PLA2G2A Human Pre-designed siRNA Set A contains three designed siRNAs for PLA2G2A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS17567
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Research Areas:
Pla2g2a Mouse Pre-designed siRNA Set A contains three designed siRNAs for Pla2g2a gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS17514
Target:
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Gpr132 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Gpr132 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P990683
CAS No.: 144058-40-2
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Cat. No.: HY-184442
Target:
Research Areas:
GPR132 antagonist-2 is a G2A (GPR132) antagonist with an IC50 of 0.69 μM. GPR132 antagonist-2 exerts weak stabilizing effects on the bromodomain of BRD2 and exhibits selectivity for non-olfactory GPCRs. GPR132 antagonist-2 inhibits G2A activation, blocks downstream inositol monophosphate accumulation, reverses G2A-mediated TRPV1 sensitization, suppresses 9-HODE-mediated capsaicin-induced TRPV1 responses, and activates FPR3. GPR132 antagonist-2 can be used in studies related to neuropathic pain .
Cat. No.: HY-RS05656
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GPR132 Human Pre-designed siRNA Set A contains three designed siRNAs for GPR132 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-N15770
CAS No.: 2489675-56-9
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Target:
Cat. No.: HY-RS23971
Target:
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Gpr132 Rat Pre-designed siRNA Set A contains three designed siRNAs for Gpr132 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS24027
Target:
Research Areas:
Pla2g2a Rat Pre-designed siRNA Set A contains three designed siRNAs for Pla2g2a gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P75977Y
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Phospholipase A2, membrane associated; EF; GIIC sPLA2
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
