3040121-49-8
Chemical Structure
SB-583355
- CAS No.: 3040121-49-8
- Formula:C29H32N2O4
- Molecular Weight:472.58
InChIKey: LFKOKWUSIRSBHS-SANMLTNESA-N
SMILES: OC1=CC=C(C(N[C@H](C(NC2CCCCC2)=O)CC3=CC=CC=C3)=O)C=C1C4=CC=C(C=C4)OC
Biological Activity: SB-583355 (Compound 56) is a potent G2A antagonist. SB-583355 can be prepared by a Suzuki reaction between 4-methoxyphenyl boronic acid and 3-bromo-4-hydroxybenzoic acid following the conditions followed by an amide coupling reaction. SB-583355 blocks the activation of G2A mediated either by 9-HOPE or T-10148 in human G2A expressing CHO-K1 cells. SB-583355 can be studied in research for inflammation, myeloid leukemia, and neuropathic pain[1].
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SB-583355 | SB-583355 (Compound 56) is a potent G2A antagonist. SB-583355 can be prepared by a Suzuki reaction between 4-methoxyphenyl boronic acid and 3-bromo-4-hydroxybenzoic acid following the conditions followed by an amide coupling reaction. SB-583355 blocks the activation of G2A mediated either by 9-HOPE or T-10148 in human G2A expressing CHO-K1 cells. SB-583355 can be studied in research for inflammation, myeloid leukemia, and neuropathic pain. | |||||||||||||||||||||
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