17 Results for "

GML

" in MedChemExpress (MCE) Product Catalog:
Products (17)

17 Results for "GML" in MCE Product Catalog:

37
37 Publications Verification
Cat. No.: HY-19805
CAS No.: 52029-86-4
Target:  

CaMK AMPK Autophagy

Research Areas:  

Metabolic Disease

STO-609 is a selective and cell-permeable inhibitor of the Ca 2+/calmodulin-dependent protein kinase kinase (CaM-KK), with Ki values of 80 and 15 ng/mL for recombinant CaM-KKα and CaM-KKβ, respectively. STO-609 inhibits AMP-activated protein kinase kinase (AMPKK) activity in HeLa cell lysates with an IC50 ~0.02 g/ml.
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5
5 Cited Publications
Cat. No.: HY-P1956
CAS No.: 70024-90-7
Synonyms: Human serum albumin
HSA Protein (Human serum albumin) is the most abundant protein in plasma and is a major determinant of plasma oncotic pressure. HSA Protein exhibits antioxidant, anticoagulant, anti-inflammatory, anti-platelet aggregation activities as well as colloid osmotic action. HSA Protein can block the inhibitory effect of GML on human T cells, providing protective function for T cells. HSA Protein is also associated with cardiovascular diseases and can partially prevent the LPS (HY-D1056) induced oxidative stress, as well as the upregulation of NF-κB, NF-κB, and peroxynitrite (ONOO ?) in the vascular wall, contributing to the reduction of blood pressure .
This product is recombinant HSA Protein expressed in a microbial expression system.
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2
2 Cited Publications
Cat. No.: HY-B1831A
CAS No.: 192564-14-0
Synonyms: LY333328 diphosphate
Target:  

Bacterial Antibiotic

Research Areas:  

Infection Inflammation/Immunology

Oritavancin diphosphate (LY333328 diphosphate), a semisynthetic derivative of Vancomycin (HY-B0671), is an orally active glycopeptide antibiotic with bactericidal activity against gram-positive organisms. Oritavancin diphosphate shows antibacterial effect against B. anthracis, such as Ames strain with a MIC value of 0.015 g/mL. Oritavancin diphosphate inhibits cell wall synthesis and disrupts the membrane potential. Oritavancin diphosphate inhibits ArlS kinase activity thereby interfering the signal transduction. Oritavancin diphosphate enters cells by adsorptive endocytosis, which drives it to lysosomes, where it exerts antibiotic activity .
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1
1 Cited Publications
Cat. No.: HY-P1956A
CAS No.: 70024-90-7
Synonyms: Human serum albumin (Cell culture grade, Endotoxin<0.125 EU/mg)
HSA Protein (Cell culture grade, Endotoxin<0.125 EU/mg) (Human serum albumin (Cell culture grade, Endotoxin<0.125 EU/mg)) is the most abundant protein in plasma and is a major determinant of plasma oncotic pressure. HSA Protein (Cell culture grade, Endotoxin<0.125 EU/mg) exhibits antioxidant, anticoagulant, anti-inflammatory, anti-platelet aggregation activities as well as colloid osmotic action. HSA Protein (Cell culture grade, Endotoxin<0.125 EU/mg) can block the inhibitory effect of GML on human T cells, providing protective function for T cells. HSA Protein (Cell culture grade, Endotoxin<0.125 EU/mg) is also associated with cardiovascular diseases and can partially prevent the LPS (HY-D1056) induced oxidative stress, as well as the upregulation of NF-κB, iNOS, and peroxynitrite (ONOO ?) in the vascular wall, contributing to the reduction of blood pressure. HSA Protein (Cell culture grade, Endotoxin<0.125 EU/mg) can be used for in vitro cell culture .
This product is human serum albumin recombinantly expressed in an Escherichia coli expression system.
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Cat. No.: HY-19805A
CAS No.: 1173022-21-3
Target:  

CaMK AMPK Autophagy

Research Areas:  

Metabolic Disease

STO-609 acetate is a selective and cell-permeable inhibitor of the Ca 2+/calmodulin-dependent protein kinase kinase (CaM-KK), with Ki values of 80 and 15 ng/mL for recombinant CaM-KKα and CaM-KKβ, respectively. STO-609 acetate inhibits AMP-activated protein kinase kinase (AMPKK) activity in HeLa cell lysates with an IC50 ~0.02 g/ml.
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Cat. No.: HY-B1831
CAS No.: 171099-57-3
Synonyms: LY 333328; Orbactiv
Target:  

Antibiotic Bacterial

Research Areas:  

Infection Inflammation/Immunology

Oritavancin (LY 333328), a semisynthetic derivative of Vancomycin (HY-B0671), is an orally active glycopeptide antibiotic with bactericidal activity against gram-positive organisms. Oritavancin shows antibacterial effect against B. anthracis, such as Ames strain with a MIC value of 0.015 g/mL. Oritavancin inhibits cell wall synthesis and disrupts the membrane potential. Oritavancin inhibits ArlS kinase activity thereby interfering the signal transduction. Oritavancin enters cells by adsorptive endocytosis, which drives it to lysosomes, where it exerts antibiotic activity .
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Cat. No.: HY-RS05521
Research Areas:  

Others

GML Human Pre-designed siRNA Set A contains three designed siRNAs for GML gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-N8256
CAS No.: 77480-55-8
Synonyms: Mycousunin
Target:  

Fungal

Research Areas:  

Infection

(–)-Mycousnine is a microbial metabolite and derivative of Usnic Acid (HY-N0656) originally isolated from M. nawae that has antibacterial and antifungal activities. It is active against the Gram-positive bacteria B. subtilis, K. rhizophila, and S. aureus (MICs=4, 8, and 4 g/ml, respectively) but not the Gram-negative bacteria E. coli, S. typhimurium, and K. pneumoniae (MICs=>128 g/ml for all).2 (–)-Mycousnine is also active against the fungi T. mentagrophytes, T. rubrum, and C. albicans (MICs=25, 25, and 100 μg/mL, respectively).
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Cat. No.: HY-N9179
CAS No.: 29043-07-0
3′,4′,5′,5,6,7-Hexamethoxyflavone is a flavonoid with antiprotozoal activity. 3′,4′,5′,5,6,7-Hexamethoxyflavone inhibits trypanosoma bruceirhodesiense with IC50 of 21.3 μM (8.58 g/mL) .
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Cat. No.: HY-B1831AR
CAS No.: 192564-14-0
Synonyms: LY333328 diphosphate (Standard)
Oritavancin (diphosphate) (Standard) is the analytical standard of Oritavancin (diphosphate). Oritavancin diphosphate (Standard), a semisynthetic derivative of Vancomycin (HY-B0671), is an orally active glycopeptide antibiotic with bactericidal activity against gram-positive organisms. Oritavancin diphosphate (Standard) shows antibacterial effect against B. anthracis, such as Ames strain with a MIC value of 0.015 g/mL. Oritavancin diphosphate (Standard) inhibits cell wall synthesis and disrupts the membrane potential. Oritavancin diphosphate (Standard) inhibits ArlS kinase activity thereby interfering the signal transduction. Oritavancin diphosphate (Standard) enters cells by adsorptive endocytosis, which drives it to lysosomes, where it exerts antibiotic activity .
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Cat. No.: HY-168371
CAS No.: 161923-56-4
1-Palmitoyl-2-13(S)-HODE-sn-glycero-3-PC (13-HODE-PC) is an oxidized phospholipid that contains Palmitic acid (HY-N0830) and 13(S)-HODE (HY-113884B) at the sn-1 and sn-2 positions, respectively. 1-Palmitoyl-2-13(S)-HODE-sn-glycero-3-PC has the ability to compete for the binding of 125I-NO2-LDL (5 g/mL) to CD36-transfected 293 cells, with the IC50 of > 200 μM .
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Cat. No.: HY-W111690
CAS No.: 57384-24-4
Synonyms: Dilithium tetrachloromanganese(2-)
Manganese(II) chloride bislithium chloride complex solution,0.956 g/mL at 25 °C, 0.5M in THF (Dilithium tetrachloromanganese(2-)) is an inorganic coordination complex, commonly used as a dedicated homogeneous catalyst in organic synthesis and battery research .
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Cat. No.: HY-N13938
CAS No.: 106486-77-5
Target:  

Others

Azinomycin A is highly cytotoxic, and the cytotoxicity to L5178Y cell IC50 is 0.07 g/mL .
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Cat. No.: HY-N15046
CAS No.: 108147-17-7
Target:  

Others

Barminomycin I shows a strong inhibition of P388 leukemia cells with IC50 of about 0.00001 g/mL .
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Cat. No.: HY-N15047
CAS No.: 108089-33-4
Target:  

Others

Barminomycin II shows a strong inhibition of P388 leukemia cells with IC50 of about 0.00002 g/mL .
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Cat. No.: HY-N14558
CAS No.: 57800-11-0
3',8-Dihydroxy-4',6,7-trimethoxyisoflavone is found in the strain of Streptomyces sp. 3',8-Dihydroxy-4',6,7-trimethoxyisoflavone is a catechole-O-methyltransferase inhibitor (IC50 is 0.2 g/mL) .
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Cat. No.: HY-N21984
CAS No.: 1932043-30-5
(3S,4S)-4-Hydroxy-3,6-dimethyl-3,4-dihydronaphthalen-1 (2H)-one is a tetralone derivative. (3S,4S)-4-Hydroxy-3,6-dimethyl-3,4-dihydronaphthalen-1 (2H)-one shows weak inhibitory activity against arachidonic acid-induced platelet aggregation, and exhibits no positive inotropic activity at the concentration of 10 -5 g/mL .
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