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Cat. No.: HY-N13938

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Azinomycin A

Azinomycin A is an antitumor antibiotic. Azinomycin A exhibits cytotoxic activity and antitumor effects against murine tumors. Azinomycin A shows antibacterial activity against Gram-negative and Gram-positive bacteria. Azinomycin A can be used for research on leukemia and bacterial infections.

For research use only. We do not sell to patients.

CAS No.: 106486-77-5
Formula: C₃₀H₃₃N₃O₁₀
Molecular Weight:595.60

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

Azinomycin A Chemical Structure

CAS No.: 106486-77-5

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

All Antibiotic Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
L5178Y	IC50	0.07 mg/mL	Cytotoxicity against murine L5178Y leukemia cells. Cytotoxicity against murine L5178Y leukemia cells.	21327255

In Vitro

Azinomycin A shows potent in vitro cytotoxic activity against L5178Y murine leukemia cells with an IC₅₀ of 0.07 μg/mL^[1].
Azinomycin A exhibits antibacterial activity against Staphylococcus aureus with an MIC of 6.25 μg/mL and against Klebsiella pneumonia ATCC 10031 with an MIC of 3.13 μg/mL^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Related Protocols :

Chemical Information

CAS No. 106486-77-5
Molecular Weight 595.60
Formula C₃₀H₃₃N₃O₁₀
SMILES

O=C(C1=CC(OC)=CC2=C1C=CC=C2C)O[C@@H]([C@@]3(CO3)C)C(N/C(C(NCC(C)=O)=O)=C4N5[C@@]([C@H]([C@@H]/4OC(C)=O)O)([H])C5)=O
Structure Classification
- Others
Initial Source
- Microorganisms
Streptomyces sahachiroi
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Foulke-Abel J, et al. Mode of action and biosynthesis of the azabicycle-containing natural products azinomycin and ficellomycin. Natural product reports. 2011 Apr;28(4):693-704. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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