8 Results for "

HPV-positive

" in MedChemExpress (MCE) Product Catalog:
Products (8)

8 Results for "HPV-positive" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-P99144A

Target:  

PD-1/PD-L1

Research Areas:  

Inflammation/Immunology Cancer

Anti-Mouse PD-1 Antibody (S-5001) is a selective inhibitor targeting PD-1, blocking the PD-1/PD-L1 immune checkpoint axis through competitive binding to PD-1. Anti-Mouse PD-1 Antibody (S-5001) works by reversing the tumor immunosuppressive microenvironment and reactivating the anti-tumor activity of cytotoxic T lymphocytes. It can be used in research on tumors such as melanoma and HPV-positive oropharyngeal squamous cell carcinoma. Anti-Mouse PD-1 Antibody (S-5001) is often combined with photothermal therapy, chemotherapy, etc., to enhance efficacy .
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1
1 Cited Publications
Cat. No.: HY-113794
CAS No.: 675104-49-1
Purity:  99.76%
Synonyms: SSYA10-001
Target:  

Filovirus

Research Areas:  

Infection

DSHS00884 is a potent human papillomavirus E6 inhibitor with an IC50 of 10 μM .
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Cat. No.: HY-163901
CAS No.: 945142-65-4
Target:  

HPV Apoptosis

Research Areas:  

Infection Cancer

E6-272 is a human papillomavirus 16 (HPV 16) inhibitor. E6-272 induces Apoptosis. E6-272 inhibits the proliferation of HPV-positive cells. E6-272 can be used in the research of cervical cancer .
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Cat. No.: HY-172265
CAS No.: 3115268-06-6
Target:  

PROTACs FKBP

Research Areas:  

Cancer

FKBP12 PROTAC FM4 is a PROTAC degrader of FKBP12, with a DC50 value of 0.09-0.22 nM. FKBP12 PROTAC FM4 inhibits global protein synthesis, induces apoptosis, and selectively reduces the viability of cervical cancer cells expressing MTH1-E6 and FKBP12 F36V-tagged SARS1. FKBP12 PROTAC FM4 is applicable to research related to HPV-positive cervical cancer .
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Cat. No.: HY-N15103
CAS No.: 178550-62-4
Target:  

Antibiotic HPV

Hydroxymycotrienin B is an ansamycin group antibiotic (triene-ansamycin) found in culture broths of Bacillus sp. BMJ958-62F4. Hydroxymycotrienin B inhibits HPV-positive cervical cancer cell growth 3~10 times more strongly than HPV-negative cervical cancer cells. Hydroxymycotrienin B can be used for the research of human cervical cancer .
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Cat. No.: HY-N14752
CAS No.: 178550-61-3
Hydroxymycotrienin A is an ansamycin group antibiotic with anticancer effects. Hydroxymycotrienin A suppresses integrated HPV18 E6 and E7 gene expression. Hydroxymycotrienin A inhibits growth of HPV-positive cervical cancer cells, stabilizes conformational mutant p53 R175H and contact mutant p53 R273H via non-covalent interactions, and acts as a non-covalent pharmacological chaperone. Hydroxymycotrienin A can be used for the research of human cervical cancer and non-small cell lung cancer (NSCLC) .
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Cat. No.: HY-183670
CAS No.: 3038340-43-8
Target:  

JAK STAT Apoptosis

Research Areas:  

Infection Cancer

JAK2-IN-21 is a Janus kinase 2 (JAK2) inhibitor with an IC50 of 12.25 nM. JAK2-IN-21 inhibits the JAK2/STAT3/STAT5 tumor-promoting signaling pathway and reduces JAK2 protein expression. JAK2-IN-21 exhibits selective cytotoxicity against HPV-positive cancer cells and induces cancer cell apoptosis. JAK2-IN-21 can be used in the research of HPV-positive cervical cancer .
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Cat. No.: HY-N20712
CAS No.: 59632-76-7
Anisomelic acid is a human papillomavirus HPV16 E6 and HPV E7 depletor . Anisomelic acid directly interacts with HPV16 E6, promotes its ubiquitination and proteasomal degradation by recruiting E3 ubiquitin ligase, downregulates E6 and facilitates E7 degradation. Anisomelic acid induces endogenous mitochondrial apoptosis, activates caspase-3, causes cleavage of PARP, and triggers p53-independent endogenous apoptosis by depleting cIAP2. Anisomelic acid can be used in research related to HPV-positive cancers and cervical cancer .
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