Hydroxymycotrienin B
Hydroxymycotrienin B is an ansamycin group antibiotic (triene-ansamycin) found in culture broths of Bacillus sp. BMJ958-62F4. Hydroxymycotrienin B inhibits HPV-positive cervical cancer cell growth 3~10 times more strongly than HPV-negative cervical cancer cells. Hydroxymycotrienin B can be used for the research of human cervical cancer.
For research use only. We do not sell to patients.
- CAS No.: 178550-62-4
- Formula: C36H48N2O9
- Molecular Weight:652.77
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Hydroxymycotrienin B (3 days) inhibits the growth of HPV-positive human cervical cancer cell lines (SiHa, CaSki, HeLa) 3-10 times more potently than HPV-negative human cervical cancer cell lines (C33A, HT-3), with IC50 values ranging from 0.45 to 0.85 μg/mL for HPV-positive lines and 3.5 to 5.0 μg/mL for HPV-negative lines[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 178550-62-4
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Molecular Weight 652.77
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Formula C36H48N2O9
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SMILES
O=C1C=C2NC(CC(/C=C/C=C/C=C/CC(C(C(/C(C)=C/CCC(C2=O)=C1O)OC(C(C)NC(C3CCCCC3)=O)=O)C)O)OC)=O
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Structure Classification
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Initial Source
Bacillus sp. BMJ958-62F4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Hydroxymycotrienin B Related Classifications
HY-N15103 Related Classifications
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