23 Results for "

IL1R1

" in MedChemExpress (MCE) Product Catalog:
Products (23)

23 Results for "IL1R1" in MCE Product Catalog:

56
56 Publications Verification
Cat. No.: HY-108841
CAS No.: 143090-92-0
Purity:  99.40%
Synonyms: Kineret; Anakinra
Raleukin (Kineret) is a recombinant, nonglycosylated human interleukin-1 receptor (IL-1R) antagonist. Raleukin significantly reduces neutrophil accumulation in blood vessels and brain infarct volume as well as improves motor coordination performance in ischemic stroke mice model. Anakinra can be used to study chronic inflammatory disorders like rheumatoid arthritis and cardiovascular recurrence post-myocardial infarction .
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6
6 Cited Publications
Cat. No.: HY-P1110
CAS No.: 185413-30-3
Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

AF12198 is a potent, selective and specific peptide antagonist for human type I interleukin-1 receptor (IL1-R1) (IC50=8 nM) but not the human type II receptor (IC50=6.7 µM) or the murine type I receptor (IC50>200 µM). AF12198 inhibits IL-1-induced IL-8 production (IC50=25 nM) and IL-1-induced intercellular adhesion molecule-1 (ICAM-1) expression (IC50=9 nM) in vitro. AF12198 has anti-inflammatory activities and blocks responses to IL-1 in vivo .
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Cat. No.: HY-108822
CAS No.: 501081-76-1
Purity:  ≥95.0%
Synonyms: Arcalyst; IL 1 Trap; Interleukin 1 Trap

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Rilonacept (Arcalyst), a dimeric fusion protein, is a interleukin 1 inhibitor. Rilonacept consists of the ligand-binding domains of the extracellular portions of the IL-1R components linked to the Fc portion of human IgG1. Rilonacept can be used for the research of cryopyrin-associated periodic syndromes .
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Cat. No.: HY-P10474
CAS No.: 1200829-06-6
Target:  

Drug Isomer

Research Areas:  

Others

RYTVELA is a deriviative of the peptide antagonist of interleukin-1 receptor 1 (IL-1R1) d-(RYTVELA) (HY-P10353) that contains all L-amino acids .
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Cat. No.: HY-RS20038
Research Areas:  

Others

Il1r1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Il1r1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P990321
Synonyms: MEDI 8968

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

AMG-108 is a humanized antibody expressed in CHO cells, targeting IL-1R1/CD121a. AMG-108 is composed of a huIgG2 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 144.62 kDa. The isotype control for AMG-108 can refer to Human IgG2 kappa, Isotype Control (HY-P99002).
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Cat. No.: HY-RS06720
Research Areas:  

Others

IL1R1 Human Pre-designed siRNA Set A contains three designed siRNAs for IL1R1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS26541
Research Areas:  

Others

Il1r1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Il1r1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-174626
Target:  

mRNA

Research Areas:  

Inflammation/Immunology

Human IL1R1 mRNA encodes the human interleukin 1 receptor type 1 (IL1R1) protein, a cytokine receptor that belongs to the interleukin-1 receptor family. IL1R1 is an important mediator involved in many cytokine-induced immune and inflammatory responses.
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Cat. No.: HY-P99140
Anti-Mouse IL-1R Antibody (JAMA-147) is an anti-mouse IL-1R IgG2b antibody inhibitor derived from host Armenian Hamster. Anti-Mouse IL-1R Antibody (JAMA-147) diminishes Spp1hi-TAM-mediated T cell suppression. Anti-Mouse IL-1R Antibody (JAMA-147) can be used for the researches of inflammation, metabolic disease and infection, such as diabetes .
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Cat. No.: HY-E70731
Target:  

IRAK

Research Areas:  

Inflammation/Immunology

The IRAK4 protein is a serine/threonine protein kinase that is critical for initiating the innate immune response through the Toll-like receptor (TLR) and IL-1R signaling pathways. After TLR is activated, it rapidly forms the Myddosome with IRAK2. IRAK4 aa104-460 Recombinant Human Active Protein Kinase is a recombinant IRAK4 aa104-460 protein that can be used to study IRAK4 aa104-460-related functions .
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Cat. No.: HY-183344
CAS No.: 3056856-56-2
Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

IL-1β-IN-4 is a selective IL-1β competitive binder. IL-1β-IN-4 interferes with the interaction between IL-1β and its cognate receptor IL-1R1, with an IC50 of 8.3 μM. IL-1β-IN-4 can be used in studies related to inflammatory and immune diseases .
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Cat. No.: HY-P70286
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL1R1; IL-1R-Alpha; Prev. IL1RA; Interleukin 1 Receptor Alpha, Type I; Prev. IL1R; Interleukin-1 Receptor, Type I; CD121 Antigen-Like FamILy Member A; Interleukin 1 Receptor, Type I; Interleukin-1 Receptor Type 1; CD121a Antigen; Interleukin-1 Receptor Ty
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Cat. No.: HY-P74823
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL1R1; IL-1R-Alpha; Prev. IL1RA; Interleukin 1 Receptor Alpha, Type I; Prev. IL1R; Interleukin-1 Receptor, Type I; CD121 Antigen-Like FamILy Member A; Interleukin 1 Receptor, Type I; Interleukin-1 Receptor Type 1; CD121a Antigen; Interleukin-1 Receptor Ty
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Cat. No.: HY-P74822
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL1R1; IL-1R-Alpha; Prev. IL1RA; Interleukin 1 Receptor Alpha, Type I; Prev. IL1R; Interleukin-1 Receptor, Type I; CD121 Antigen-Like FamILy Member A; Interleukin 1 Receptor, Type I; Interleukin-1 Receptor Type 1; CD121a Antigen; Interleukin-1 Receptor Ty
Species:  
Rat
Source:  
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Cat. No.: HY-P76995
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL1R1; IL-1R-Alpha; Prev. IL1RA; Interleukin 1 Receptor Alpha, Type I; Prev. IL1R; Interleukin-1 Receptor, Type I; CD121 Antigen-Like FamILy Member A; Interleukin 1 Receptor, Type I; Interleukin-1 Receptor Type 1; CD121a Antigen; Interleukin-1 Receptor Ty
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Cat. No.: HY-P76996
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL1R1; IL-1R-Alpha; Prev. IL1RA; Interleukin 1 Receptor Alpha, Type I; Prev. IL1R; Interleukin-1 Receptor, Type I; CD121 Antigen-Like FamILy Member A; Interleukin 1 Receptor, Type I; Interleukin-1 Receptor Type 1; CD121a Antigen; Interleukin-1 Receptor Ty
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Cat. No.: HY-P74821
Purity:  ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: IL1R1; IL-1R-Alpha; Prev. IL1RA; Interleukin 1 Receptor Alpha, Type I; Prev. IL1R; Interleukin-1 Receptor, Type I; CD121 Antigen-Like FamILy Member A; Interleukin 1 Receptor, Type I; Interleukin-1 Receptor Type 1; CD121a Antigen; Interleukin-1 Receptor Ty
Species:  
Rat
Source:  
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Cat. No.: HY-P72569
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL1R1; IL-1R-Alpha; Prev. IL1RA; Interleukin 1 Receptor Alpha, Type I; Prev. IL1R; Interleukin-1 Receptor, Type I; CD121 Antigen-Like FamILy Member A; Interleukin 1 Receptor, Type I; Interleukin-1 Receptor Type 1; CD121a Antigen; Interleukin-1 Receptor Ty
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Cat. No.: HY-P73185
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: IL1R1; IL-1R-Alpha; Prev. IL1RA; Interleukin 1 Receptor Alpha, Type I; Prev. IL1R; Interleukin-1 Receptor, Type I; CD121 Antigen-Like FamILy Member A; Interleukin 1 Receptor, Type I; Interleukin-1 Receptor Type 1; CD121a Antigen; Interleukin-1 Receptor Ty
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